Abstract:
:Granulomatosis with polyangiitis (GPA) is an idiopathic vasculitis of medium and small arteries, characterized by necrotizing granulomatous inflammation. GPA typically affects upper and lower respiratory tract with coexisting glomerulonephritis. This disease is generally characterized by antineutrophil cytoplasm antibodies (ANCA), nevertheless, there are rare cases with negative ANCA. GPA affects people at any age, with predominance of the sixth and seventh decade of life. In 80%-95% of the patients the first symptoms of GPA are otorhinolaryngological manifestations of head and neck including nose/sinuses, ears, eyes, larynx/trachea, oral cavity, and salivary glands. Diagnosis of GPA is based on Criteria of the American College of Rheumatology. In clinical practice diagnosis, the presence of distinctive ANCA antibodies and biopsy of affected organ are crucial. GPA must be differentiated from neoplastic, infectious or inflammatory ulcerative lesions of the head and neck. The standard treatment procedure is divided into two essential phases, induction and maintenance. The induction phase is based on combination of systemic corticosteroid and immunosuppressant therapy, whereas the maintenance phase comprises corticosteroids and azathioprine/methotrexate supplementation. Surgical treatment ought to be considered for patients who are not responding to pharmacotherapy.
journal_name
Clin Exp Otorhinolaryngoljournal_title
Clinical and experimental otorhinolaryngologyauthors
Wojciechowska J,Krajewski W,Krajewski P,Kręcicki Tdoi
10.21053/ceo.2016.9.1.8subject
Has Abstractpub_date
2016-03-01 00:00:00pages
8-13issue
1eissn
1976-8710issn
2005-0720pii
ceo-2016-9-1-8journal_volume
9pub_type
杂志文章,评审abstract::Meningioma's account for around 15% of all primary brain tumors with some 10% of meningiomas arising in the posterior fossa. In rare cases, a meningioma can form around the endolymphatic sac. When formed in the posterior fossa, meningioma tumors can produce vague, non-specific vertiginous symptoms. Research has observ...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2012.5.4.234
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate serum pituitary tumor transforming gene (PTTG1) expression in laryngeal carcinoma and its relationship with the clinical pathological characteristics and prognosis. METHODS:Expression of serum PTTG1 was measured by enzyme-linked immunosorbent assay in 110 patient...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2019.00395
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:Evaluation of a new material, high-density porous polyethylene (HDPP), which is covered with fascia lata, for experimental nasal septal perforation closure. METHODS:Twenty New Zealand albino rabbits were included and divided into study and control groups. A lateral incision was made from the lateral aspect ...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2011.4.3.137
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:The internet has become an important source of medical information and a great amount of information related to allergic rhinitis (AR) is available on the internet. However, the quality of this information is still a matter of debate. Therefore, this study was conducted to assess the AR-related information o...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2010.3.1.32
更新日期:2010-03-01 00:00:00
abstract::Laser surgery (LS) or radiotherapy (RT) is normally recommended in early glottic cancer. The objective of this study was to perform a comprehensive meta-analysis of acoustic and perceptual outcomes to compare voice quality of LS or RT in early-stage glottic cancer. Data sources were obtained after searching PubMed, Go...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章,评审
doi:10.21053/ceo.2018.00990
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVES:To evaluate characteristic computed tomography (CT) and magnetic resonance (MR) imaging findings of granulocytic sarcomas of the head and neck. METHODS:The CT (n=11) and MR (n=1) images obtained from 11 patients (7 males and 4 females; mean age, 23.5 yr; age range, 1 to 69 yr) with histologically-proven gra...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2009.2.2.66
更新日期:2009-06-01 00:00:00
abstract::Allergic rhinitis (AR) is a globally increasing health problem affecting the quality of life. Specific immunotherapy is an available causal treatment changing the basic allergic mechanisms of the disease. Over one hundred years, subcutaneous immunotherapy (SCIT) was developed and proved its efficacy but many adverse e...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章,评审
doi:10.3342/ceo.2014.7.4.241
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare the effect of the presence of one or two arytenoids on early/late period swallowing-aspiration functions. METHODS:Supracricoid partial laryngectomy (SCPL) with the diagnosis of laryngeal cancer between 2012 and 2014 were retrospectively evaluated. The patients were categ...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2015.01837
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVES:To compare voice parameters in subjects with different hearing level. METHODS:The evaluation consisted of Multi-Dimensional Voice Program (MDVP) and electroglottography. Group 1 consisted of normal hearing subjects which is bilateral average hearing better than 25 decibels (dB) whereas group 2 consisted of ...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2015.01900
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVES:This study compared the survival outcomes, local control rate, and laryngeal preservation rate of various treatment strategies in the treatment of T3 squamous cell carcinoma of the glottis using proportional meta-analyses. METHODS:Twenty-five retrospective case-series studies were included in these analyses...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2017.00717
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to determine whether chronic kidney disease (CKD) is associated with hearing thresholds in the nationwide, large-scaled Korean population. METHODS:This study analyzed the data of 9,798 subjects of 19 years and older (4,387 males and 5,411 females). Urine albumin-to-creatinine ratio...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2015.01368
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVES:In laryngeal cancer, which comprises 25% of head and neck cancer, chemotherapy has come into prominence with the increase in organ-protective treatments. With such treatment, salvage surgery has increased following recurrence; the incidence of pharyngocutaneous fistula has also increased in both respiratory ...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2015.8.4.390
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVES:The aim of present study was to determine the relationship between serum zinc level and tinnitus using data from the Korea National Health and Nutrition Examination Survey (KNHANES). METHODS:The present study examined the relationship between serum zinc level and tinnitus using data from the KNHANES. A tota...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2015.8.4.335
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVES:In onco-hematological diseases, the incidence of paranasal sinuses infection dramatically increase and requires a combination of medical and surgical therapy. Balloon dilatation surgery (DS) is a minimally invasive, tissue preserving procedure. The study evaluates the results of DS for rhinosinusitis in immu...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2014.7.4.302
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVES:Endoscopic laryngopharyngeal surgery (ELPS) is a minimally invasive transoral surgery that was developed to treat superficial larygo-pharyngeal cancer, in which a mucosal lesion is resected transorally while preserving deeper structures by subepithelial injection. The purpose of this retrospective study is t...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2016.9.1.70
更新日期:2016-03-01 00:00:00
abstract:Objectives:Fibro-osseous lesions of the paranasal sinuses can present various clinical conditions. This study aimed to report the long-term clinical course of benign fibro-osseous lesions (BFOLs) in the paranasal sinuses, including clinical and radiologic features. Methods:Radiologically confirmed BFOLs except osteoma...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2020.01522
更新日期:2020-11-04 00:00:00
abstract:OBJECTIVES:The authors have treated chronic tinnitus patients using a combination of a simplified tinnitus retraining therapy (TRT) and medications, which we called modified TRT. In this clinical setting, we have attempted small-group counseling to find a time-effective equivalent of individual counseling. The aim of t...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2013.6.4.214
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVES:The prognostic significance of vertigo in patients with idiopathic sudden sensorineural hearing loss (SSNHL) remains a matter of debate because vertigo is associated with many different vestibular disorders. The purpose of this study is to determine the role of benign paroxysmal positional vertigo (BPPV) as ...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2010.3.4.199
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVES:Speech perception abilities, which vary widely among cochlear implant (CI) users, are considered to be associated with the integrity of the central auditory pathways from the auditory nerve to the cortex. Therefore, auditory evoked potentials (AEPs) are used to evaluate central auditory processing, which is ...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2012.5.S1.S6
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVES:Somatostatin inhibits lymph production and reduces lymph flow into the lymphatic duct. We hypothesized that octreotide, a long-acting somatostatin analog, would reduce drainage after neck dissection (ND) by reducing the overall lymphatic flow in the neck as well as thoracic duct flow. METHODS:From 2012 to 2...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2015.00073
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:Autologous costal cartilage is a promising alternative for mastoid obliteration. However, donor-site morbidities of the chest wall limit the use of this graft. To address this issue, we have developed a minimally-invasive technique of harvesting costal cartilage and report donor site morbidity associated wit...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2015.8.1.13
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to evaluate the advantages and limitations of using a silicon tube to support the fractured orbital floor by a transantral approach. METHODS:A retrospective study was conducted from January 2000 to December. 2011 in 51 patients with pure orbital floor fractures. The patients un...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2015.8.3.250
更新日期:2015-09-01 00:00:00
abstract::Juvenile hyaline fibromatosis (JHF) is a rare, progressive autosomal recessive disease that's characterized by papulonodular skin lesions, soft tissue masses, joint contractures, gingival hypertrophy and osteolytic bone lesions. We present here the case of a 2-yr-old boy with JHF along with a review of the relevant li...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2010.3.2.102
更新日期:2010-06-01 00:00:00
abstract:Background:The emergence of Electronic cigarettes (E-cigarettes) is creating new perceptions of the tobacco market. Unlike traditional Tabacco, the greatest advantage of E-cigarettes is, above all, that it has a less-smell, convenience, and low cost. And most of the people who smoke E-cigarettes have been believed it i...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2020.01907
更新日期:2020-12-18 00:00:00
abstract:OBJECTIVES:There have been many studies on the relationship between diabetes mellitus and presbycusis. Microangiopathy and neuropathy that's caused by chronic hyperglycemia may lead to damage to the inner ear. Several clinical studies on humans and animal studies have been performed to investigate the association betwe...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2008.1.4.211
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES:False-negative or false-positive responses in intraoperative neuromonitoring (IONM) using electromyography (EMG) in thyroid surgery pose a challenge. Therefore, we developed a novel IONM system that uses a surface pressure sensor instead of EMG to detect muscle twitching. This study aimed to investigate the ...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2018.01207
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVES:To clarify the anatomical distribution of the lingual artery in normal adult subjects through histopathologic evaluations. METHODS:Eighteen healthy cadaveric tongues were used to produce 8 paraffin-embedded tissue sections each. Length from midline raphe, depth from dorsum of tongue and the whole transverse...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2015.01137
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVES:Free flaps are widely used to reconstruct head and neck defects. Despite the improvement in the surgical techniques and the surgeons' experiences, flap failures still occur due to thrombotic occlusion after small vessels anastomosis. To reduce the possibility of flap loss as a result of thrombotic occlusion,...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.21053/ceo.2015.01781
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:To compare tinnitus patients who have normal hearing between 250 Hz and 8 kHz with normal controls with regard to the ability of each group to hear extended high-frequency pure tone thresholds. METHODS:We enrolled 18 tinnitus patients, each of whom had a threshold of HL <25 dB and threshold differences of <...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2009.2.4.169
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVES:This study prospectively evaluated postthyroidectomy syndrome (PTS) through objective and subjective voice changes following thyroidectomy of open vs. endoscopic thyroidectomy. METHODS:A prospective clinical trial (SCHBC IRB 09 26) was performed from Jan 2008 to Aug 2010 to compare the open thyroidectomy (O...
journal_title:Clinical and experimental otorhinolaryngology
pub_type: 杂志文章
doi:10.3342/ceo.2015.8.1.76
更新日期:2015-03-01 00:00:00