Does hemispheric lateralization influence therapeutic effects of transcranial direct current stimulation?

abstract：:The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury. However, it is unclear whether deferoxamine directly protects neurons from ferroptotic cell death. By comparing the survival rate and morphology of primary neurons and SH-SY5Y cells exposed to erastin, it was found that these c...

journal_title：Neural regeneration research

authors： Zhang Y,Fan BY,Pang YL,Shen WY,Wang X,Zhao CX,Li WX,Liu C,Kong XH,Ning GZ,Feng SQ,Yao X

更新日期：2020-08-01 00:00:00

abstract：:The acute effect of acupuncture on Alzheimer's disease, i.e., on brain activation during treatment, has been reported. However, the effect of long-term acupuncture on brain activation in Alzheimer's disease is unclear. Therefore, in this study, we performed long-term needling at Zusanli (ST36) or a sham point (1.5 mm ...

journal_title：Neural regeneration research

authors： Lu YJ,Cai XW,Zhang GF,Huang Y,Tang CZ,Shan BC,Cui SY,Chen JQ,Qu SS,Zhong Z,Lai XS,Steiner GZ

更新日期：2017-07-01 00:00:00

abstract：:Parkinson's disease is characterized by the loss of dopaminergic neurons in the substantia nigra. As a result, intensive efforts have focused upon mechanisms that facilitate the death of mature dopaminergic neurons. Unfortunately, these efforts have been unsuccessful in providing an effective treatment to address neur...

journal_title：Neural regeneration research

authors： Morrison BE

更新日期：2016-06-01 00:00:00

abstract：:In this study, we hypothesized that total flavonoid of Litsea coreana leve (TFLC) protects against focal cerebral ischemia/reperfusion injury. TFLC (25, 50, 100 mg/kg) was administered orally to a rat model of focal ischemia/reperfusion injury, while the free radical scavenging agent, edaravone, was used as a positive...

journal_title：Neural regeneration research

authors： Dong S,Tong X,Li J,Huang C,Hu C,Jiao H,Gu Y

更新日期：2013-12-05 00:00:00

abstract：:Motor function impairment is a common outcome of stroke. Constraint-induced movement therapy (CIMT) involving intensive use of the impaired limb while restraining the unaffected limb is widely used to overcome the effects of 'learned non-use' and improve limb function after stroke. However, the underlying mechanism of...

journal_title：Neural regeneration research

authors： Zhang B,He Q,Li YY,Li C,Bai YL,Hu YS,Zhang F

更新日期：2015-12-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia in the older population, however, the precise cause of the disease is unknown. The neuropathology is characterized by the presence of aggregates formed by amyloid-β (Aβ) peptide and phosphorylated tau; which is accompanied by progressive impairment of memory...

journal_title：Neural regeneration research

authors： Tapia-Rojas C,Inestrosa NC

更新日期：2018-10-01 00:00:00

abstract：:Neural stem/progenitor cell (NSC) transplantation has been shown to effectively improve neurological function in rats with hypoxic-ischemic brain damage. Vascular endothelial growth factor (VEGF) is a signaling protein that stimulates angiogenesis and improves neural regeneration. We hypothesized that transplantation ...

journal_title：Neural regeneration research

authors： Yao Y,Zheng XR,Zhang SS,Wang X,Yu XH,Tan JL,Yang YJ

更新日期：2016-09-01 00:00:00

abstract：:Traumatic brain injury (TBI) is characterized by primary damage to the brain from the external mechanical force and by subsequent secondary injury due to various molecular and pathophysiological responses that eventually lead to neuronal cell death. Secondary brain injury events may occur minutes, hours, or even days ...

journal_title：Neural regeneration research

authors： Martinez B,Peplow PV

更新日期：2017-11-01 00:00:00

abstract：:Human umbilical cord mesenchymal stem cells, incorporated into an amnion carrier tubes, were assessed for nerve regeneration potential in a rat nerve defect model. Damaged nerves were exposed to human amnion carriers containing either human umbilical cord mesenchymal stem cell (cell transplantation group) or saline (c...

journal_title：Neural regeneration research

authors： Li D,Wang C,Shan W,Zeng R,Fang Y,Wang P

更新日期：2012-08-15 00:00:00

abstract：:[This corrects the article on p. 770 in vol. 12, PMID: 28616034.]. ...

journal_title：Neural regeneration research

authors： Lu J,Guo Y,Guo CQ,Shi XM,Du NY,Zhao RL,Du WP,Liang JR,Zhu SP,Chen H

更新日期：2017-06-01 00:00:00

abstract：:Acupuncture has been shown to ameliorate cognitive impairment of Alzheimer's disease. Acupoints and stimulation frequency influence the therapeutic effect of electroacupuncture. Rat models of Alzheimer's disease were established by injecting amyloid beta 1-42 (Aβ1-42) into the bilateral lateral ventricles. Electroacup...

journal_title：Neural regeneration research

authors： Yu CC,Wang Y,Shen F,Kong LH,Wang YW,Zhou H,Tang L

更新日期：2018-10-01 00:00:00

abstract：:Interleukin-1α and interleukin-1β aggravate neuronal injury by mediating the inflammatory reaction following ischemic/hypoxic brain injury. It remains unclear whether interleukin-1α and interleukin-1β are released by microglia or astrocytes. This study prepared hippocampal slices that were subsequently subjected to ox...

journal_title：Neural regeneration research

authors： Wang H,Guo W,Liu H,Zeng R,Lu M,Chen Z,Xiao Q

更新日期：2013-05-05 00:00:00

abstract：:The baker's yeast Saccharomyces (S.) cerevisiae is a single-celled eukaryotic model organism widely used in research on life sciences. Being a unicellular organism, S. cerevisiae has some evident limitations in application to neuroscience. However, yeast prions are extensively studied and they are known to share some ...

journal_title：Neural regeneration research

authors： Ishikawa T

更新日期：2021-03-01 00:00:00

abstract：:Fractional anisotropy values in diffusion tensor imaging can quantitatively reflect the consistency of nerve fibers after brain damage, where higher values generally indicate less damage to nerve fibers. Therefore, we hypothesized that diffusion tensor imaging could be used to evaluate the effect of mild hypothermia o...

journal_title：Neural regeneration research

authors： Jing G,Yao X,Li Y,Xie Y,Li WX,Liu K,Jing Y,Li B,Lv Y,Ma B

更新日期：2014-01-15 00:00:00

abstract：:Acupuncture can induce changes in the brain. However, the majority of studies to date have focused on a single acupoint at a time. In the present study, we observed activity changes in the brains of healthy volunteers before and after acupuncture at Taichong (LR3) and Taixi (KI3) using resting-state functional magneti...

journal_title：Neural regeneration research

authors： Zhang SQ,Wang YJ,Zhang JP,Chen JQ,Wu CX,Li ZP,Chen JR,Ouyang HL,Huang Y,Tang CZ

更新日期：2015-02-01 00:00:00

abstract：:Anti-inflammatory and anti-oxidant agents can alleviate ischemic cerebral injury. The immunomodulary drug Setarud, which is composed of herbal extracts including Rosa canina, Urtica dioica and Tanacetum vulgare, supplemented with selenium exhibits anti-inflammatory and anti-oxidant properties. Therefore, we hypothesiz...

journal_title：Neural regeneration research

authors： Vafaee F,Zangiabadi N,Pour FM,Dehghanian F,Asadi-Shekaari M,Afshar HK

更新日期：2012-09-25 00:00:00

abstract：:Acacetin (5,7-dihydroxy-4'-methoxyflavone), a potential neuroprotective agent, has an inhibitory effect on lipopolysaccharide-induced neuroinflammatory reactions. However, whether acacetin has an effect on inflammatory corpuscle 3 (NLRP3) after cerebral ischemia-reperfusion injury has not been fully determined. This s...

journal_title：Neural regeneration research

authors： Bu J,Shi S,Wang HQ,Niu XS,Zhao ZF,Wu WD,Zhang XL,Ma Z,Zhang YJ,Zhang H,Zhu Y

更新日期：2019-04-01 00:00:00

abstract：:Three-dimensional (3D) histology utilizes tissue clearing techniques to turn intact tissues transparent, allowing rapid interrogation of tissue architecture in three dimensions. In this article, we summarized the available tissue clearing methods and classified them according to their physicochemical principles of ope...

journal_title：Neural regeneration research

authors： Lai HM,Ng HM,Wu W

更新日期：2017-01-01 00:00:00

abstract：:Serum biomarkers may play a reliable role in predicting the outcomes of patients with aneurysmal subarachnoid hemorrhage. This study retrospectively analyzed the relationship between serum biomarkers on admission and outcomes in patients with aneurysmal subarachnoid hemorrhage. We recruited 146 patients with aneurysma...

journal_title：Neural regeneration research

authors： Liu JH,Li XK,Chen ZB,Cai Q,Wang L,Ye YH,Chen QX

更新日期：2017-12-01 00:00:00

abstract：:In the present study, we examined the analgesic effect of repeated electroacupuncture at bilateral Zusanli (ST36) and Yanglingquan (GB34) once a day for 14 consecutive days in a rat model of chronic sciatic nerve constriction injury-induced neuropathic pain. In addition, concomitant changes in calcium/calmodulin-depen...

journal_title：Neural regeneration research

authors： Xu Q,Liu T,Chen S,Gao Y,Wang J,Qiao L,Liu J

更新日期：2012-06-25 00:00:00

abstract：:Gynostemma (G.) pentaphyllum (Cucurbitaceae) contains various bioactive gypenosides. Ethanol extract from G. pentaphyllum (GP-EX) has been shown to have ameliorative effects on the death of dopaminergic neurons in animal models of Parkinson's disease (PD) induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- and 6-...

journal_title：Neural regeneration research

authors： Park HJ,Zhao TT,Kim SH,Lee CK,Hwang BY,Lee KE,Lee MK

更新日期：2020-02-01 00:00:00

abstract：:The heterogeneity of traumatic brain injury (TBI)-induced secondary injury has greatly hampered the development of effective treatments for TBI patients. Targeting common processes across species may be an innovative strategy to combat debilitating TBI. In the present study, a cross-species transcriptome comparison wa...

journal_title：Neural regeneration research

authors： Yang MS,Xu XJ,Zhang B,Niu F,Liu BY

更新日期：2021-07-01 00:00:00

abstract：:TMP269 is a selective class IIA histone deacetylase inhibitor that has a protective effect on the central nervous system, whose specific mechanism of action is unclear. We aimed to reveal the optimal concentration of TMP269 for protecting against cerebral ischemia/reperfusion injury and its neuroprotective mechanism. ...

journal_title：Neural regeneration research

authors： Su L,Liang D,Kuang SY,Dong Q,Han X,Wang Z

更新日期：2020-02-01 00:00:00

abstract：:Recent studies have shown that induced expression of endogenous antioxidative enzymes thr-ough activation of the antioxidant response element/nuclear factor erythroid 2-related factor 2 (Nrf2) pathway may be a neuroprotective strategy. In this study, rat cerebral cortical neurons cultured in vitro were pretreated with...

journal_title：Neural regeneration research

authors： Wu JX,Zhang LY,Chen YL,Yu SS,Zhao Y,Zhao J

更新日期：2015-03-01 00:00:00

abstract：:Stem cell transplantation has brought new hope for the treatment of neurological diseases. The key to stem cell therapy lies in inducing the specific differentiation of stem cells into nerve cells. Because the differentiation of stem cells in vitro and in vivo is affected by multiple factors, the final differentiation...

journal_title：Neural regeneration research

authors： Ren C,Ji YQ,Liu H,Wang Z,Wang JH,Zhang CY,Guan LN,Yin PY

更新日期：2019-07-01 00:00:00

abstract：:Functional recovery after oculomotor nerve injury is very poor. Electrical stimulation has been shown to promote regeneration of injured nerves. We hypothesized that electrical stimulation would improve the functional recovery of injured oculomotor nerves. Oculomotor nerve injury models were created by crushing the ri...

journal_title：Neural regeneration research

authors： Du L,Yang M,Wan L,Wang XH,Li ST

更新日期：2016-10-01 00:00:00

abstract：:Only a few studies have considered changes in brain structures other than sensory and motor cortex after spinal cord injury, although cognitive impairments have been reported in these patients. Spinal cord injury results in chronic brain neuroinflammation with consequent neurodegeneration and cognitive decline in rode...

journal_title：Neural regeneration research

authors： Jure I,Labombarda F

更新日期：2017-07-01 00:00:00

abstract：:Three male patients were diagnosed with new cortical infarctions of the right parietal lobe on the basis of head magnetic resonance imaging; high-intensity signals indicating lesions in the right parietal lobe were noted on diffusion-weighted images at admission. Two of them presented with left hand weakness, and one ...

journal_title：Neural regeneration research

authors： Li F,Jia Y

更新日期：2012-04-25 00:00:00

abstract：:The present study involved a questionnaire survey of 156 mothers that gave birth to children with neural tube defects or had a history of pregnancy resulting in children with neural tube defects (case group) and 156 control mothers with concurrent healthy children (control group) as well as detection of mitochondrial ...

journal_title：Neural regeneration research

authors： Liu Z,Xie J,Luo T,Zhang T,Zhao X,Zhao H,Li P

更新日期：2012-02-25 00:00:00

abstract：:Single-chain variable domain fragment (scFv) 637 is an antigen-specific scFv of myasthenia gravis. In this study, scFv and human serum albumin genes were conjugated and the fusion protein was expressed in Pichia pastoris. The affinity of scFv-human serum albumin fusion protein to bind to acetylcholine receptor at the ...

journal_title：Neural regeneration research

authors： Li F,Meng F,Jin Q,Sun C,Li Y,Li H,Jin S

更新日期：2014-04-15 00:00:00