Abstract:
:Administration of doses of linoleic acid (LA) up to 36 g/d in humans raised blood levels of linoleic acid but not of its metabolites. This is probably because the conversion of LA to gamma-linolenic acid (GLA) is slow and rate-limiting. We have found that administration of relatively small amounts of GLA, up to 360 mg/d, raises human blood levels of dihomogammalinolenic acid (DGLA) and arachidonic acid (AA).
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Manku MS,Morse-Fisher N,Horrobin DFsubject
Has Abstractpub_date
1988-01-01 00:00:00pages
55-60issue
1eissn
0954-3007issn
1476-5640journal_volume
42pub_type
杂志文章abstract:OBJECTIVE:To describe drinking patterns among individuals who prefer drinking wine, beer or spirits. DESIGN:Cross-sectional study obtaining detailed information on intake of wine, beer and spirits and on frequency of alcohol intake. Adjustment for gender, age, smoking habits, educational attainment and body mass index...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600919
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:This study investigates the predictors of serum cobalamin concentrations in community-dwelling older adults and the relationship between serum cobalamin and plasma homocysteine. SUBJECTS/METHODS:Serum cobalamin and plasma homocysteine were measured by SimulTRAC-SNB radio assay and HPLC, respectiv...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0367-8
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Patients with a short bowel and receiving parenteral nutrition (PN) have an increased risk of chronic cholestasis (CC). Restoration of bowel continuity after a mesenteric infarction results in PN requirements being reduced or stopped. This study aimed to determine the prevalence of CC and whether ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.147
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Infant and young child feeding (IYCF) has not been documented in central and western China, where anaemia is prevalent. To support policy advocacy, we assessed IYCF and anaemia there using standardized methods. SUBJECTS/METHODS:A community-based, cross-sectional survey of 2244 children aged 6-23 ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.98
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:We previously demonstrated that acute exposure to hypoxia (3 h at 3000 m) increased oxidative stress markers. Thus, by using the 'living high-training low' (LHTL) method, we further hypothesized that intermittent hypoxia associated with endurance training alters the prooxidant/antioxidant balance....
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章
doi:10.1038/ejcn.2008.30
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The European Food Safety Authority approved a health claim (ID558) relating to lowered postprandial glycaemia when fructose replaces 30% of sucrose in foods and beverages. We assessed the effects of partial replacement of sucrose with fructose on serum glucose, uric acid and blood pressure. SUBJE...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41430-018-0134-x
更新日期:2018-12-01 00:00:00
abstract::The development of atherosclerotic vascular disease is influenced by multiple factors present since early age. Abnormal lipid metabolism, a major cause of atherosclerosis, results from genetic predisposition and is influenced by a variety of exogenous conditions. This article reviews the published studies of serum cho...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1993-09-01 00:00:00
abstract:OBJECTIVE:Iodine deficiency is a serious public health problem worldwide which is associated with mental retardation and cretinism. In view of a high incidence of transient neonatal hypothyroidism and a relatively high mean cord blood thyrotropin (TSH) concentration, a pilot study was carried out to analyse the urine i...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Healthy eating advice is informed, in part, by dietary surveys that rely on self-reported data. Misreporting of food intake may distort relationships between diet and health outcomes. This study directly quantified the food groups that were under-reported or over-reported in common dietary assessm...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0199-6
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the in vivo effects of moderate consumption of red wine, beer and spirits on antioxidants, antioxidant enzymes and antioxidant capacity. DESIGN:Randomized, diet-controlled, cross-over study. SUBJECTS:Twelve apparently healthy, non-smoking middle-aged men were included; 11 of them completed the s...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601061
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVES:To evaluate body fatness in subjects complying with common public health guidelines for lipid and alcohol intake as well as physical activity participation. SUBJECTS:A sample of 358 male subjects who participated in phase 1 of the Quebec Family Study. DESIGN:The association between adiposity, lipid and alc...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVE:To evaluate dietary habits and nutritional status of Spanish school children and adolescents, and their relationship with the Mediterranean Diet. DESIGN:Cross-sectional study by face-to-face interview. SETTING:Free living children and adolescents of all Spanish regions. SUBJECTS:A random sample of 3166 peo...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601812
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:We aimed to assess the effects on mild morbidity of a richly micronutrient-fortified complementary/replacement food given to Zambian infants aged 6-18 months. Previous results (The Chilenje Infant Growth, Nutrition and Infection Study Team, 2010) showed an increase in the rate of hospital referral...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2011.103
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Vitamin B(12) (B(12)) deficiency is common in Indians and a major contributor to hyperhomocysteinemia, which may influence fetal growth, risk of type II diabetes and cardiovascular disease. The purpose of this paper was to study the effect of physiological doses of B(12) and folic acid on plasma t...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2010.15
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To study the effect of Lactobacillus helveticus fermented milk on sleep and health perception in elderly healthy subjects. SUBJECTS:The study included 29 healthy elderly subjects aged 60-81 years. METHODS:Prospective, randomized, double-blind and placebo-controlled, with a crossover design. The study includ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602898
更新日期:2009-01-01 00:00:00
abstract::The possible relationship between consumption of trans fatty acids (TFAs) and risk of insulin resistance or development of diabetes mellitus type II has been considered by a number of human and animal studies over the past decade. This review evaluates the evidence, and concludes that there is limited evidence for a w...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/ejcn.2010.240
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:The acute phase response (APR) influences indicators of iron status. A recent WHO/CDC consultation recommended concurrent measurement of alpha-1-acid-glycoprotein (AGP) in surveys to control for the APR, and aid in interpreting iron status. They proposed further exploratory analyses using AGP. We examined wh...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2008.33
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Vitamin D status has been associated with fetal growth and offspring's bone mass in some observational studies. We characterize the trajectory of total maternal serum 25-hydroxyvitamin D [25(OH)D] concentration by race and examine whether vitamin D status is associated with neonatal anthropometry ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0212-0
更新日期:2019-03-01 00:00:00
abstract::The principal metabolic function of vitamin B6 is in amino acid metabolism, although the greater part of the body's vitamin B6 is in muscle, associated with glycogen phosphorylase, and the vitamin also has an important role in the actions of steroid hormones. It is usual to calculate vitamin B6 requirements relative t...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1989-05-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Milk contributes with saturated fat, but randomized controlled trials (RCT) on the effects of dairy on the risk of type 2 diabetes (T2D) where dairy is given as whole foods are scarce. The objective of our study was to investigate the long-term effects of semi-skimmed milk on insulin sensitivity a...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41430-017-0006-9
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To investigate the impact of intensive lifestyle education on dietary practices, exercise and metabolic measurements in people with insulin-dependent diabetes mellitus (IDDM). DESIGN:Sixty-one volunteer subjects with IDDM were randomised to intensive (Group 1) or standard (Group 2) education programmes for s...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1600478
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:This study investigated whether postprandial metabolic responses to bread could be lowered by substituting high amylose maize starch for a part of the flour. DESIGN AND SUBJECTS:Eight healthy subjects consumed test meals of equivalent nutritional composition based on white wheat bread, bread rich in amylose ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600718
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of fatty liver and alanine aminotransferase (ALT) elevation in obese Japanese women and to clarify the factors contributing to fatty change and ALT elevation in the cohort. DESIGN:Cross-sectional and population-based study. SUBJECTS:From 4366 women who received their annual healt...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601956
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The aim of this study was to evaluate the association of serum 25-hydroxyvitamin D (25(OH)D) with disability and frequency of relapses in relapsing-remitting multiple sclerosis (MS) patients. SUBJECTS/METHODS:The study included 184 patients with relapsing-remitting MS who were receiving immune-mo...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.51
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To assess total daily energy expenditure (TDEE) and patterns of physical activity among Swedish male and female adolescents and to relate the amount and intensity of physical activity to existing recommendations (energy expenditure equal to or above 12.4 kJ/kg/day or accumulation of 30 min/day in moderate phy...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600918
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVES:To determine the content of glutamine in major food proteins. SUBJECTS/METHODS:We used a validated 131-food item food frequency questionnaire (FFQ) to identify the foods that contributed the most to protein intake among 70,356 women in the Nurses' Health Study (NHS, 1984). The content of glutamine and other...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.110
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Cross-sectionally, educational attainment is strongly associated with the prevalence of obesity, but this association is less clear for weight change during adult life. The objective of this study is to examine the association between educational attainment and weight change during adult life in t...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2012.55
更新日期:2012-08-01 00:00:00
abstract::We previously detected that ~50% of kidney transplant patients (KTPs) present sarcopenia using the first European Working Group on Sarcopenia in Older People (EWGSOP1) consensus. Our aim was to evaluate the agreement between the sarcopenia diagnosis using EWGSOP1 and the new consensus (EWGSOP2) in KTPs. A cross-sectio...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-019-0535-5
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To compile curves for Body Mass Index (BMI) for Italian children and adolescents. DESIGN:Cross sectional study. SETTING:All primary and secondary schools of Verona, Italy between October 1986 and January 1987. SUBJECTS:20,796 males and 21,073 females children, aged 3-19 y. METHODS:Weight and height were m...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600326
更新日期:1997-01-01 00:00:00
abstract::Food fortification can deliver essential micronutrients to large population segments without modifications in consumption pattern, suggesting that fortified foods may be formulated for populations at risk for fragility fractures. This scoping review determined the extent to which randomized controlled studies have bee...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/ejcn.2016.42
更新日期:2016-10-01 00:00:00