Abstract:
INTRODUCTION:To assess the clinical features, outcomes, complications, and cost-effectiveness of shockwave lithotripsy (SWL), flexible ureterorenoscopy (FURS), and percutaneous nephrolithotomy (PCNL) in the treatment of lower pole (LP) stones (10-20 mm) in a large tertiary referral center. PATIENTS AND METHODS:Consecutive patients treated for solitary LP stones (10-20 mm) between 2008 and 2013 were identified from a prospective database. SWL was used as primary treatment in all cases (following a stone multidisciplinary team assessment), with FURS and PCNL reserved for SWL contraindications, failure, or patient choice. "Success" was defined as stone free and/or clinically insignificant stone fragments (≤3 mm) at 1 and 3 months follow-up. Effect of anatomy on SWL success was determined from using CT images and regression analysis. Average cost per treatment modality (including additional second-line treatments) was calculated for each group using the National Health Service England 2014/15 National Tariff Healthcare Resource Group codes. RESULTS:Two hundred twenty-five patients were included (mean age 54.9; median stone size 12 mm). One hundred ninety-eight (88%), 21 (9.3%), and 6 (2.7%) patients underwent SWL, FURS, and PCNL as primary treatments, respectively, for median stone sizes of 12, 12, and 20 mm. Overall success rates were 82.8%, 76.1%, and 66.7%, respectively (p < 0.05). Sixty-three percent of patients undergoing primary SWL were effectively treated after one session. Anatomical analysis determined infundibulopelvic angle and infundibular length to be significantly different in patients effectively treated with SWL (p = 0.04). The average cost per treatment modality was also significantly lower for SWL (£750) than for FURS (£1261) or PCNL (£2658) (p < 0.01). CONCLUSION:SWL is both an efficacious and cost-effective primary treatment for patients with solitary LP stones (10-20 mm). The majority of patients can be effectively treated with primary SWL in a dedicated stone center, with the benefits of a short length of stay, low complication, and auxiliary treatment rates. The referral of such patients to high-volume lithotripsy centers with demonstrable outcomes should be given due consideration.
journal_name
J Endouroljournal_title
Journal of endourologyauthors
Chan LH,Good DW,Laing K,Phipps S,Thomas BG,Keanie JY,Tolley DA,Cutress MLdoi
10.1089/end.2016.0825subject
Has Abstractpub_date
2017-05-01 00:00:00pages
510-516issue
5eissn
0892-7790issn
1557-900Xjournal_volume
31pub_type
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journal_title:Journal of endourology
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doi:10.1089/end.1995.9.85
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pub_type: 临床试验,杂志文章
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journal_title:Journal of endourology
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pub_type: 杂志文章,多中心研究
doi:10.1089/end.2015.0054
更新日期:2015-09-01 00:00:00
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journal_title:Journal of endourology
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2019.0493
更新日期:2020-03-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.20.33
更新日期:2006-01-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2015.0178
更新日期:2015-09-01 00:00:00
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更新日期:2017-05-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
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journal_title:Journal of endourology
pub_type: 杂志文章
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2007.0410
更新日期:2008-08-01 00:00:00
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journal_title:Journal of endourology
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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