Fcγ1 fragment of IgG1 as a powerful affinity tag in recombinant Fc-fusion proteins: immunological, biochemical and therapeutic properties.

abstract：:Lipopolysaccharide (LPS), the major component of the outer membrane of Gram-negative bacteria, often pose a serious risk not only when delivered in the bloodstream but also in air, the environment and several industrial fields such as pharmaceutics or food. LPS is constituted of three regions; the O-specific chain, th...

journal_title：Critical reviews in biotechnology

authors： Basauri A,González-Fernández C,Fallanza M,Bringas E,Fernandez-Lopez R,Giner L,Moncalián G,de la Cruz F,Ortiz I

更新日期：2020-05-01 00:00:00

abstract：:Nitrilases are widely distributed in nature and are able to hydrolyze nitriles into their corresponding carboxylic acids and ammonia. In industry, nitrilases have been used as green biocatalysts for the production of high value-added products. To date, biocatalysts are considered to be important alternatives to chemic...

journal_title：Critical reviews in biotechnology

authors： Shen JD,Cai X,Liu ZQ,Zheng YG

更新日期：2021-02-01 00:00:00

abstract：:Vitamin C (L-ascorbic acid; AsA) is the major soluble antioxidant found in plants and is also an essential component of human nutrition. Although numerous biotechnological methods have been exploited to increase its yield, pressures such as commercial competition and environmental concerns make it urgent to find a new...

journal_title：Critical reviews in biotechnology

authors： Zhang L,Wang Z,Xia Y,Kai G,Chen W,Tang K

更新日期：2007-07-01 00:00:00

abstract：:Cypripedium orchids have high horticultural value. The populations of most species are very geographically restricted and they are becoming increasingly rare due to the destruction of native habitats and illegal collection. Reduction of the commercial value through large-scale propagation in vitro is a preferable opti...

journal_title：Critical reviews in biotechnology

authors： Zeng S,Zhang Y,Teixeira da Silva JA,Wu K,Zhang J,Duan J

更新日期：2014-12-01 00:00:00

abstract：:Utilization of microbial oil for biodiesel production has gained growing interest due to the increase in prices and the shortage of the oils and fats traditionally used in biodiesel production. However, it is still in the laboratory study stage due to the high cost of production. Employing organic wastes as raw materi...

journal_title：Critical reviews in biotechnology

authors： Chen J,Li J,Zhang X,Tyagi RD,Dong W

更新日期：2018-09-01 00:00:00

abstract：:Triterpenoid saponins are structurally diverse secondary metabolites. They are the main active ingredient of many medicinal plants and have a wide range of pharmacological effects. Traditional production of triterpenoid saponins, directly extracted from cultivated plants, cannot meet the rapidly growing demand of phar...

journal_title：Critical reviews in biotechnology

authors： Yao L,Wang J,He J,Huang L,Gao W

更新日期：2021-01-20 00:00:00

abstract：:Metabolic engineering is crucial in the development of production strains for platform chemicals, pharmaceuticals and biomaterials from renewable resources. The central carbon metabolism (CCM) of heterotrophs plays an essential role in the conversion of biomass to the cellular building blocks required for growth. Yet,...

journal_title：Critical reviews in biotechnology

authors： Kopp D,Sunna A

更新日期：2020-11-01 00:00:00

abstract：:Arbuscular mycorrhizal fungi (AMF) form widespread symbiotic associations with 80% of known land plants. They play a major role in plant nutrition, growth, water absorption, nutrient cycling and protection from pathogens, and as a result, contribute to ecosystem processes. Salinity stress conditions undoubtedly limit ...

journal_title：Critical reviews in biotechnology

authors： Kumar A,Dames JF,Gupta A,Sharma S,Gilbert JA,Ahmad P

更新日期：2015-01-01 00:00:00

abstract：:Grapes are one of the most cultivated fruit crops worldwide. Either for wine or juice production, grape processing generates a large amount of residues that must be treated, disposed of or reused properly to reduce their pollution load before being applied to the soil. In this review, a special focus is given to the t...

journal_title：Critical reviews in biotechnology

authors： Gómez-Brandón M,Lores M,Insam H,Domínguez J

更新日期：2019-06-01 00:00:00

abstract：:The beneficial effects of endophytes on plant growth are important for agricultural ecosystems because they reduce the need for fertilizers and decrease soil and water pollution while compensating for environmental perturbations. Endophytic fungi are a novel source of bioactive secondary metabolites; moreover, recentl...

journal_title：Critical reviews in biotechnology

authors： Khan AL,Hussain J,Al-Harrasi A,Al-Rawahi A,Lee IJ

更新日期：2015-03-01 00:00:00

abstract：:Cross-linked enzyme aggregate (CLEA) technology has been regarded as an effective carrier-free immobilization method. This method is very attractive due to its simplicity and robustness, as well as for the possibility of using the crude enzyme extract and the opportunity to co-immobilize multiple different enzymes. Th...

journal_title：Critical reviews in biotechnology

authors： Cui JD,Jia SR

更新日期：2015-03-01 00:00:00

abstract：:The emergence of new gene-editing technologies is profoundly transforming human therapeutics, agriculture, and industrial biotechnology. Advances in clustered regularly interspaced short palindromic repeats (CRISPR) have created a fertile environment for mass-scale manufacturing of cost-effective products ranging from...

journal_title：Critical reviews in biotechnology

authors： Brinegar K,K Yetisen A,Choi S,Vallillo E,Ruiz-Esparza GU,Prabhakar AM,Khademhosseini A,Yun SH

更新日期：2017-11-01 00:00:00

abstract：:Butanol is a precursor of many industrial chemicals, and a fuel that is more energetic, safer and easier to handle than ethanol. Fermentative biobutanol can be produced using renewable carbon sources such as agro-industrial residues and lignocellulosic biomass. Solventogenic clostridia are known as the most preeminent...

journal_title：Critical reviews in biotechnology

authors： Jiménez-Bonilla P,Wang Y

更新日期：2018-05-01 00:00:00

abstract：:In recent years, the advances in microbiology show that biofilms are structurally complex, dynamic and adaptable systems including attributes of multicellular organisms and miscellaneous ecosystems. One may distinguish between beneficial and harmful biofilms appearing in daily life as well as various industrial proces...

journal_title：Critical reviews in biotechnology

authors： Böl M,Ehret AE,Bolea Albero A,Hellriegel J,Krull R

更新日期：2013-06-01 00:00:00

abstract：:The availability of binders to different functional domains of the same protein or to physiologically co-operating proteins allows for the simultaneous inhibition of independent downstream signaling pathways. This multi-target approach represents a promising therapeutic strategy, as demonstrated in the case of the syn...

journal_title：Critical reviews in biotechnology

authors： de Marco A

更新日期：2013-03-01 00:00:00

abstract：:Erythritol is a natural sweetener commonly used in the food and pharmaceutical industries. Produced by microorganisms as an osmoprotectant, it is an ideal sucrose substitute for diabetics or overweight persons due to its almost zero calorie content. Currently, erythritol is produced on an industrial scale through the ...

journal_title：Critical reviews in biotechnology

authors： Rzechonek DA,Dobrowolski A,Rymowicz W,Mirończuk AM

更新日期：2018-06-01 00:00:00

abstract：:α-d-Galactosidases (EC 3.2.1.22) are enzymes employed in a number of useful bio-based applications. We have depicted a comprehensive general survey of α-d-galactosidases from different origin with special emphasis on marine example(s). The structures of natural α-galactosyl containing compounds are described. In addit...

journal_title：Critical reviews in biotechnology

authors： Bakunina IY,Balabanova LA,Pennacchio A,Trincone A

更新日期：2016-01-01 00:00:00

abstract：:Filamentous fungi play an important role not only in the bio-manufacturing of value-added products, but also in bioenergy and environmental research. The bioprocess manipulation of filamentous fungi is more difficult than that of other microbial species because of their different pellet morphologies and the presence o...

journal_title：Critical reviews in biotechnology

authors： Zhang J,Zhang J

更新日期：2016-12-01 00:00:00

abstract：:Experimental design is a form of process analysis in which certain factors are selected to obtain the desired responses of interest. It may also be used for the determination of the effects of various independent factors on a dependent factor. The bioengineering discipline includes many different areas of scientific i...

journal_title：Critical reviews in biotechnology

authors： Keskin Gündoğdu T,Deniz İ,Çalışkan G,Şahin ES,Azbar N

更新日期：2016-01-01 00:00:00

abstract：:The Vitamin K series, particularly menaquinone, have been attracting research attention, due to the potential in reducing both osteoporosis and cardiovascular diseases. This review provides an overview of the types of vitamin K and their health benefits. This is followed by a critical review of the various biotechnolo...

journal_title：Critical reviews in biotechnology

authors： Berenjian A,Mahanama R,Kavanagh J,Dehghani F

更新日期：2015-06-01 00:00:00

abstract：:Natural cellular microenvironment consists of spatiotemporal gradients of multiple physical (e.g. extracellular matrix stiffness, porosity and stress/strain) and chemical cues (e.g. morphogens), which play important roles in regulating cell behaviors including spreading, proliferation, migration, differentiation and a...

journal_title：Critical reviews in biotechnology

authors： Wang L,Li Y,Huang G,Zhang X,Pingguan-Murphy B,Gao B,Lu TJ,Xu F

更新日期：2016-01-01 00:00:00

abstract：:Proteases have a broad range of applications in industrial processes and products and are representative of most worldwide enzyme sales. The genus Bacillus is probably the most important bacterial source of proteases and is capable of producing high yields of neutral and alkaline proteolytic enzymes with remarkable pr...

journal_title：Critical reviews in biotechnology

authors： Contesini FJ,Melo RR,Sato HH

更新日期：2018-05-01 00:00:00

abstract：:Endocrine-disrupting compounds (EDCs) can interfere with endocrine systems and bio-accumulate through the food chain and even decrease biodiversity in contaminated areas. This review discusses a critical overview of recent research progress in the biotransformation of EDCs (including polychlorinated biphenyl and nonyl...

journal_title：Critical reviews in biotechnology

authors： Huang D,Guo X,Peng Z,Zeng G,Xu P,Gong X,Deng R,Xue W,Wang R,Yi H,Liu C

更新日期：2018-08-01 00:00:00

abstract：:l-Leucine, as an essential branched-chain amino acid for humans and animals, has recently been attracting much attention because of its potential for a fast-growing market demand. The applicability ranges from flavor enhancers, animal feed additives and ingredients in cosmetic to specialty nutrients in pharmaceutical ...

journal_title：Critical reviews in biotechnology

authors： Wang YY,Xu JZ,Zhang WG

更新日期：2019-08-01 00:00:00

abstract：:Prokaryotic expression systems are superior in producing valuable recombinant proteins, enzymes and therapeutic products. Conventional microbial technology is evolving gradually and amalgamated with advanced technologies in order to give rise to improved processes for the production of metabolites, recombinant biophar...

journal_title：Critical reviews in biotechnology

authors： Gupta SK,Shukla P

更新日期：2016-12-01 00:00:00

abstract：:Terpenes are natural products with a remarkable diversity in their chemical structures and they hold a significant market share commercially owing to their distinct applications. These potential molecules are usually derived from terrestrial plants, marine and microbial sources. In vitro production of terpenes using p...

journal_title：Critical reviews in biotechnology

authors： Paramasivan K,Mutturi S

更新日期：2017-12-01 00:00:00

abstract：:Calf rennet, which consists of over 90% chymosin, is commonly used in cheese industries for the curdling of milk. Various animal, plant and microbial sources have been exploited as possible alternatives to calf rennet. The coagulating properties of the enzymatic preparations (coagulants) from these sources differ in t...

journal_title：Critical reviews in biotechnology

authors： Kumar A,Grover S,Sharma J,Batish VK

更新日期：2010-12-01 00:00:00

abstract：:Lactic acid, an anaerobic product of glycolysis, can be theoretically produced by synthetic route; however, it is commercially produced by homo-fermentative batch mode of operations. Factors affecting its production and strategies improving it are considered while devising an optimized protocol. Although a hetero-ferm...

journal_title：Critical reviews in biotechnology

authors： Yadav AK,Chaudhari AB,Kothari RM

更新日期：2011-03-01 00:00:00

abstract：:Phytoremediation uses plants and associated microbes to remove pollutants from the environment and is considered a promising bioremediation method. Compared with well-described single contaminant treatments, the number of studies reporting phytoremediation of soil mixed pollutants has increased recently. Endophytes, i...

journal_title：Critical reviews in biotechnology

authors： He W,Megharaj M,Wu CY,Subashchandrabose SR,Dai CC

更新日期：2020-02-01 00:00:00

abstract：:Anthocyanin biosynthesis in Arabidopsis is a convenient and relatively simple model for investigating the basic principles of secondary metabolism regulation. In recent years, many publications have described links between anthocyanin biosynthesis and general defense reactions in plants as well as photomorphogenesis a...

journal_title：Critical reviews in biotechnology

authors： Bulgakov VP,Avramenko TV,Tsitsiashvili GS

更新日期：2017-09-01 00:00:00