Abstract:
:A case of an epithelial-lined (true) adrenal cyst is reported. Although over 300 adrenal cysts have been reported in the literature, true cysts are rare. In this case, a 4.0 cm cyst lined by cuboidal to flattened cells with bland cytologic features was incidentally found at autopsy. Immunologic studies performed on formalin-fixed, paraffin-embedded sections demonstrated that the cells expressed keratins (AE1/AE3+, CAM 5.2+, and MAK-6+) and were negative for epithelial membrane antigen, vimentin, factor VIII, and desmin. Normal adrenal cortical and medullary cells did not express keratins, suggesting that the cyst lining was not derived from either adrenal cortex or medulla. A mesothelial origin, with a pathogenesis analogous to the formation of primary cysts of the spleen, is proposed.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Medeiros LJ,Weiss LM,Vickery AL Jrdoi
10.1016/0046-8177(89)90017-8subject
Has Abstractpub_date
1989-05-01 00:00:00pages
491-2issue
5eissn
0046-8177issn
1532-8392pii
0046-8177(89)90017-8journal_volume
20pub_type
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