Epithelial-lined (true) cyst of the adrenal gland: a case report.

Abstract:

:A case of an epithelial-lined (true) adrenal cyst is reported. Although over 300 adrenal cysts have been reported in the literature, true cysts are rare. In this case, a 4.0 cm cyst lined by cuboidal to flattened cells with bland cytologic features was incidentally found at autopsy. Immunologic studies performed on formalin-fixed, paraffin-embedded sections demonstrated that the cells expressed keratins (AE1/AE3+, CAM 5.2+, and MAK-6+) and were negative for epithelial membrane antigen, vimentin, factor VIII, and desmin. Normal adrenal cortical and medullary cells did not express keratins, suggesting that the cyst lining was not derived from either adrenal cortex or medulla. A mesothelial origin, with a pathogenesis analogous to the formation of primary cysts of the spleen, is proposed.

journal_name

Hum Pathol

journal_title

Human pathology

authors

Medeiros LJ,Weiss LM,Vickery AL Jr

doi

10.1016/0046-8177(89)90017-8

subject

Has Abstract

pub_date

1989-05-01 00:00:00

pages

491-2

issue

5

eissn

0046-8177

issn

1532-8392

pii

0046-8177(89)90017-8

journal_volume

20

pub_type

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