Abstract:
:Understanding the impact of helminth infections on clinical malaria is useful for designing effective malaria control strategies. Plenty of epidemiological studies have been conducted to unravel the nature of interactions between Plasmodium and helminth infection. Careful broad summarization of the existing literature suggests that Schistosoma mansoni and hookworm infections may increase the risk of clinical malaria and associated morbidities, but Trichuris trichiura infection is not associated with the occurrence of clinical malaria and related outcomes. However, findings about effect of Ascaris lumbricoides and Schistosoma haematobium infection on clinical malaria are contradictory. Furthermore, the nature of relationship of helminth infection with severe malaria has also not been determined with certainty. This review summarizes the findings of epidemiological studies of Plasmodium and helminth coinfection, placing greater emphasis on the impact of the coinfection on malaria. Possible reasons for the heterogeneity of the findings on malaria and helminth coinfections are also discussed.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Degarege A,Erko Bdoi
10.1155/2016/3083568subject
Has Abstractpub_date
2016-01-01 00:00:00pages
3083568eissn
2314-6133issn
2314-6141journal_volume
2016pub_type
杂志文章,评审abstract::To better understand the molecular mechanism for the pathogenesis of follicular thyroid carcinoma (FTC), this study aimed at identifying key miRNAs and their target genes associated with FTC, as well as analyzing their interactions. Based on the gene microarray data GSE82208 and microRNA dataset GSE62054, the differen...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/2725192
更新日期:2019-03-28 00:00:00
abstract::Pinelliae Rhizoma Praeparatum Cum Alumine (PRPCA) is useful for eliminating dampness and phlegm in clinical settings, targeting the main mechanisms of insomnia as defined in traditional Chinese medicine. However, little is known regarding the sedative and hypnotic effects of PRPCA. In the present study, we examined th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6198067
更新日期:2019-04-28 00:00:00
abstract::Extra-intestinal E. coli are emerging as a global threat due to their diffusion as opportunistic pathogens and, above all, to their wide set of antibiotic resistance determinants. There are still many gaps in our knowledge of their origin and spread pathways, although food animals have been adjudicated vehicles for pa...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/8714975
更新日期:2018-11-18 00:00:00
abstract::Hepatocellular carcinoma (HCC) is the second leading cause of cancer deaths in Taiwan. CD44, one of the well-known tumor markers, plays an essential role in tumor cell differentiation, invasion, and metastasis. We investigated the CD44 single-nucleotide polymorphisms (SNPs) with environmental risk factors related to H...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/231474
更新日期:2014-01-01 00:00:00
abstract::The aim of the present study was to investigate the suitability of insoluble Eudragit® water dispersions (NE, NM, RL, and RS) for direct high-shear granulation of very soluble levetiracetam in order to decrease its burst effect from HPMC K100M matrices. The process characteristics, ss-NMR analysis, in vitro dissolutio...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/8043415
更新日期:2019-03-05 00:00:00
abstract::It has been described renal damage in rats with vascular calcification. The organic anion transporter 5 (Oat5) is only expressed in kidney, and its urinary excretion was proposed as potential early biomarker of renal injury. The aim of this study was to evaluate the Oat5 renal expression and its urinary excretion in a...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/283429
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To investigate if software simulation is practical for quantifying random error (RE) in phantom dosimetry. MATERIALS AND METHODS:We applied software error simulation to an existing dosimetry study. The specifications and the measurement values of this study were brought into the software (R version 3.0.2) to...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/596858
更新日期:2015-01-01 00:00:00
abstract::Neurotrophic keratitis (NK) is a rare degenerative disease of the cornea caused by an impairment of corneal sensory innervation, characterized by decreased or absent corneal sensitivity resulting in epithelial keratopathy, ulceration, and perforation. The aetiopathogenesis of corneal sensory innervation impairment in ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/805876
更新日期:2015-01-01 00:00:00
abstract::This study investigated the effects of a pragmatic lifestyle intervention in obese adults with continuous positive airway pressure-treated obstructive sleep apnoea hypopnoea syndrome (OSAHS). Sixty patients were randomised 1 : 1 to either a 12-week lifestyle intervention or an advice-only control group. The interventi...
journal_title:BioMed research international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1155/2014/102164
更新日期:2014-01-01 00:00:00
abstract::Cumulative evidence has indicated that there is an important role for adult hippocampal neurogenesis in cognitive function. With the increasing prevalence of cognitive decline associated with neurodegenerative diseases among the ageing population, physical exercise, a potent enhancer of adult hippocampal neurogenesis,...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/403120
更新日期:2014-01-01 00:00:00
abstract::Endothelial barrier dysfunction, which is a serious problem that occurs in various inflammatory conditions, permits extravasation of serum components into the surrounding tissues, leading to edema formation and organ failure. Pigment epithelium-derived factor (PEDF), which is a major endogenous antagonist, has been im...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/791825
更新日期:2015-01-01 00:00:00
abstract:Background:Waldenström macroglobulinemia (WM) is a rare, indolent B-cell lymphoma. Clinically, chromosome 6q deletion (6q del) including loss of the B lymphocyte-induced maturation protein 1 gene (BLIMP-1) is reported to be associated with poor prognosis. However, it remains unclear how the underlying biological mechan...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6728128
更新日期:2018-10-04 00:00:00
abstract::Protein phosphorylation is one of the most widespread regulatory mechanisms in eukaryotes. Over the past decade, phosphorylation site prediction has emerged as an important problem in the field of bioinformatics. Here, we report a new method, termed Random Forest-based Phosphosite predictor 2.0 (RF-Phos 2.0), to predi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3281590
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the value of ecological momentary assessment in evaluating physical activity among children, adolescents, and adults. It also determines whether ecological momentary assessment fulfills the criteria of validity, reliability, objectivity, norms, and standardization appli...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/915172
更新日期:2014-01-01 00:00:00
abstract::Background. Whether additional benefit can be achieved with the use of L-carnitine (L-C) in patients with chronic heart failure (CHF) remains controversial. We therefore performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the effects of L-C treatment in CHF patients. Methods. Pubmed, Ovid Emba...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析,评审
doi:10.1155/2017/6274854
更新日期:2017-01-01 00:00:00
abstract::Inorganic arsenic (iAs) exposure induces a decrease in glucose type 4 transporter (GLUT4) expression on the adipocyte membrane, which may be related to premature births and low birth weight infants in women exposed to iAs at reproductive age. The aim of this study was to analyze the effect of sodium arsenite (NaAsO2) ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/175025
更新日期:2015-01-01 00:00:00
abstract::Restriction enzymes are the main defence system against foreign DNA, in charge of preserving genome integrity. Lactococcus raffinolactis BGTRK10-1 expresses LraI Type II restriction-modification enzyme, whose activity is similar to that shown for EcoRI; LraI methyltransferase protects DNA from EcoRI cleavage. The gene...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/5657085
更新日期:2018-01-29 00:00:00
abstract:Objectives:This study aims to determine the changing in hip anatomy parameters with age and reveals the reason for the extorsion of lower extremity in the aged. Design:Retrospective study. Participants:One hundred and forty patients who had received imaging check of the femur and acetabulum between October 2013 and O...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1507979
更新日期:2018-09-27 00:00:00
abstract::The aim of the present study was to evaluate the antitumor potential of iminoflavones in in vitro and in vivo anticancer models. Preliminary screening in various cancer cell lines revealed four potential iminoflavones out of which IMF-8 was taken based on its activity against colon cancer cells. This was further confi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/569130
更新日期:2014-01-01 00:00:00
abstract::Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different cord regions, inclu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/916136
更新日期:2013-01-01 00:00:00
abstract::Despite many advances in the diagnosis and treatment of colorectal cancer (CRC), its incidence and mortality rates continue to make an impact worldwide and in some countries rates are mounting. Over the past decade, liquid biopsies have been the object of fundamental and clinical research with regard to the different ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/5953036
更新日期:2019-12-04 00:00:00
abstract:OBJECTIVE:Lipoprotein-associated phospholipase A2 (Lp-PLA2), a marker of vascular inflammation, is associated with cardiovascular disease. This prospective study of an inception cohort aimed to investigate whether the level of Lp-PLA2 is associated with subclinical atherosclerosis in patients with rheumatoid arthritis ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/673018
更新日期:2015-01-01 00:00:00
abstract::TMJ disc related diseases are difficult to be cured due to the poor repair ability of the disc. TMJ-SDSCs were ideal cell sources for cartilage tissue engineering which have been widely used in hyaline cartilage regeneration. Fibrin gel has been demonstrated as a potential scaffold for neocartilage formation. The aim ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/454021
更新日期:2014-01-01 00:00:00
abstract:Background:This study explored the therapeutic efficacy of standard triple therapy combined with sucralfate suspension gel as well as the mechanisms of action in mouse models of H. pylori infection. Materials and Methods:C57BL/6J mice were randomly divided into 5 groups: NC (natural control), HP (H. pylori infection),...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/4936318
更新日期:2020-08-31 00:00:00
abstract:Background:Diagnosis using reliable tools and treatment following in vitro antimicrobial susceptibility tests are critical to proper addressing of antibiotic-resistant Salmonella infection. Methodology:A cross-sectional study was conducted to assess the practice of diagnosis and treatment of salmonellosis in Addis Aba...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6406405
更新日期:2018-05-23 00:00:00
abstract::The use of modern surgical dressings to prevent wound complications and surgical site infection (SSI) after minimally invasive total knee arthroplasty (MIS-TKA) is lacking. In a prospective, randomized, controlled study, 240 patients were randomized to receive either AQUACEL Ag Surgical dressing (study group) or a sta...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2017/1262108
更新日期:2017-01-01 00:00:00
abstract::The aim of this study was to investigate the potential of microparticles based on biocompatible phytolipids [Softisan® 154 (SF) (hydrogenated palm oil) and super-refined sunseed oil (SO)] and polyethylene glycol- (PEG-) 4000 to improve intravaginal delivery of miconazole nitrate (MN) for effective treatment of vulvova...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3714329
更新日期:2018-06-06 00:00:00
abstract:CONTEXT:IGF1R overexpression appears to be a prognostic biomarker of metastatic pediatric adrenocortical tumors. However, the molecular mechanisms that are implicated in its upregulation remain unknown. Aim. To investigate the potential mechanisms involved in IGF1R overexpression. PATIENTS AND METHODS:We studied 64 ad...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2014/936031
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Physical activity is associated with reduced mortality and morbidity. Cardiac rehabilitation (CR) is an effective intervention for patients with cardiovascular disease (CVD). Unfortunately, women are less likely to engage in, or sustain, regular physical activity. Objectives were to (1) describe women's guid...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/121030
更新日期:2013-01-01 00:00:00
abstract::T. reesei is an efficient cellulase producer and biomass degrader. To improve xylitol production in Trichoderma reesei strains by genetic engineering, two approaches were used in this study. First, the presumptive D-xylulokinase gene in T. reesei (xyiH), which has high homology to known fungi D-xylulokinase genes, was...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/169705
更新日期:2014-01-01 00:00:00