Vitamin K-dependent carboxylase activity in fetal rat lung: developmental effects of dexamethasone and triiodothyronine.

abstract：:Cerebral blood flow (CBF) was measured by means of Celabeled microspheres in infant (20-day-old) and adult (3-month-old) rats, anesthetised with Na-5-ethyl-5-(1-methylpropyl)2-thiobarbituric acid. Cerebral arteriovenous differences of acetoacetate, D-beta-hydroxybutyrate, glucose, lactate, and oxygen and brain DNA con...

journal_title：Pediatric research

authors： Dahlquist G,Persson B

更新日期：1976-11-01 00:00:00

abstract：:Skin fibroblasts derived from 6 patients with cystic fibrosis (CF), 1-6 months old, and from 6 age matched donors were investigated for their ability to accumulate cyclic adenosine 3':5'-monophosphate (c-AMP) in response to isoproterenol and prostaglandin E1 (PGE1) using strictly defined culture conditions. In order t...

journal_title：Pediatric research

authors： Roscher AA,Schmid AJ,Hadorn B,Wiesmann UN

更新日期：1980-03-01 00:00:00

abstract：:Wolfram syndrome 1 (WS1) is a rare autosomal recessive neurodegenerative disease characterized by diabetes insipidus, diabetes mellitus, optic atrophy, deafness, and other abnormalities. WS1 usually results in death before the age of 50 years. The pathogenesis of WS1 is ascribed to mutations of human WFS1 gene on chro...

journal_title：Pediatric research

authors： Rigoli L,Bramanti P,Di Bella C,De Luca F

更新日期：2018-05-01 00:00:00

abstract：:Premature birth causes significant health risks of the neonate and increases the cost for neonatal care. Urogenital infection, often caused by Gram-negative bacteria, is a known risk factor. Toll-like receptor-4 (TLR4) is the major endotoxin-signaling receptor and as such is crucial for the initiation of the innate im...

journal_title：Pediatric research

authors： Lorenz E,Hallman M,Marttila R,Haataja R,Schwartz DA

更新日期：2002-09-01 00:00:00

abstract：:Leptin, a hormone secreted by adipocytes, is elevated in blood of obese adults. It is unknown whether the concentration is affected by gender, ethnicity, age, or stage of sexual maturation in children. We measured serum leptin levels in 183 children and 27 young adults using a double-antibody ELISA assay. Body fat mas...

journal_title：Pediatric research

authors： Ellis KJ,Nicolson M

更新日期：1997-10-01 00:00:00

abstract：:Early-life stress has been shown to destabilize the homeostatic synaptic plasticity and compromise the developing brain to the later encountered insults. This study would determine the long-term epileptogenic effect of neonatal isolation (NI) on early-life seizure. There were five groups: normal rearing (NR) rats; NI ...

journal_title：Pediatric research

authors： Lai MC,Lui CC,Yang SN,Wang JY,Huang LT

更新日期：2009-10-01 00:00:00

abstract：:Groups of newborn rats were transthoracically inoculated with 1 X 10(6) type III group B streptococci/g body wt, either alone or in combination with 1.5 microgram/g body wt of type-specific antibody derived from hybridoma cell lines. Ninety-four percent of the animals who received bacteria alone died. In contrast, non...

journal_title：Pediatric research

authors： Christensen RD,Rothstein G,Hill HR,Pincus SH

更新日期：1983-10-01 00:00:00

abstract：:Normative body composition during the first 2 y of life was derived from a prospective study of 76 children. We present 1) fat free mass (FFM) and its components, and fat mass (FM), 2) incremental growth rates partitioned into chemical components, and 3) age-specific and gender-specific constants for converting chemic...

journal_title：Pediatric research

authors： Butte NF,Hopkinson JM,Wong WW,Smith EO,Ellis KJ

更新日期：2000-05-01 00:00:00

abstract：:The effects of early protein-deficiency on lung development were studied in the rat. Newborn male rats were nursed in groups of eight. Control dams and pups received a 15% protein diet during the whole experiment. Test mothers only received 12 and 8% proteins from the 7th and the 14th day of lactation. Test rats fed a...

journal_title：Pediatric research

authors： Kalenga M,Henquin JC

更新日期：1987-07-01 00:00:00

abstract：:Twenty-two reported cases of neuroblastoma missed by the mass screening programs were reviewed (six cases in Sapporo City where a quantitative measurement for both vanillylmandelic acid (VMA) and homovanillic acid (HVA) is used and 16 cases in the districts of qualitative judgment only for VMA), and some potential fac...

journal_title：Pediatric research

authors： Nishi M,Miyake H,Takeda T,Takasugi N,Sato Y,Hanai J,Kawai T

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:To examine differences in comorbidities and surgical management based on socioeconomics in hospitalized children with Crohn's disease (CD). METHODS:Using the Kids' Inpatient Database for 2006-2012, we identified patients (<21 years) with a CD diagnosis. Cases were analyzed and stratified by median parental ...

journal_title：Pediatric research

authors： McLoughlin RJ,Klouda A,Hirsh MP,Cleary MA,Lightdale JR,Aidlen JT

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Cognitive impairment has been documented in adult diabetes but is unclear in pediatric diabetes. No study had been conducted to explore the relationship between attention-deficit/hyperactivity disorder (ADHD) and diabetes. Using a population-based data set, we aimed to examine the association between ADHD an...

journal_title：Pediatric research

authors： Chen HJ,Lee YJ,Yeh GC,Lin HC

更新日期：2013-04-01 00:00:00

abstract：:Epithelial hyperplasia is an early feature of the renal and biliary lesions in autosomal recessive polycystic kidney disease (ARPKD). To explore the cellular basis of this hyperplasia we isolated, cultured, and characterized biliary tract epithelium from common bile duct explants of mice with ARPKD (the BPK mouse) and...

journal_title：Pediatric research

authors： Nauta J,Sweeney WE,Rutledge JC,Avner ED

更新日期：1995-06-01 00:00:00

abstract：:In the original article, the legend within Fig. 3 incorrectly read as '*p < 0.10, **p < 0.05, ***p > 0.01'. This has now been changed to '*p < 0.10, **p < 0.05, ***p < 0.01'. This has been corrected in both the PDF and HTML versions of the Article. The authors would like to apologise for this error. ...

journal_title：Pediatric research

authors： Benavides A,Metzger A,Tereshchenko A,Conrad A,Bell EF,Spencer J,Ross-Sheehy S,Georgieff M,Magnotta V,Nopoulos P

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Early brain development is closely dictated by distinct neurobiological principles. Here, we aimed to map early trajectories of structural brain wiring in the neonatal brain. METHODS:We investigated structural connectome development in 44 newborns, including 23 preterm infants and 21 full-term neonates scan...

journal_title：Pediatric research

authors： Keunen K,van der Burgh HK,de Reus MA,Moeskops P,Schmidt R,Stolwijk LJ,de Lange SC,Išgum I,de Vries LS,Benders MJ,van den Heuvel MP

更新日期：2018-12-01 00:00:00

abstract：:This study was made to determine the life span of adult red cells transfused to early preterm infants. Nineteen very preterm infants (birth weight, 878.7 +/- 221 g; gestational age, 26.8 +/- 1.5 wk at birth) were sampled weekly after their last blood transfusion to determine the level (%) of fetal Hb in their circulat...

journal_title：Pediatric research

authors： Bard H,Widness JA

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:The aim of this study is to compare new pediatric nomograms for clinical parameters from 2D echocardiography. METHODS:2D pediatric echocardiographic parameters from four recent nomograms were used for statistical analysis. To assess the accuracy of the predictive models from each study, namely multivariate,...

journal_title：Pediatric research

authors： Cantinotti M,Scalese M,Giordano R,Assanta N,Marchese P,Franchi E,Viacava C,Koestenberger M,Jani V,Kutty S

更新日期：2020-04-24 00:00:00

abstract：:Innate immunity and urinary tract response play a central role in the development of urinary tract infection (UTI). Heat shock protein (HSP) 72 and Toll-like receptor (TLR) 4 are among the key elements of innate defence mechanisms. This study assesses the role of HSPA1B A(1267)G and TLR4 A(896)G polymorphisms using al...

journal_title：Pediatric research

authors： Karoly E,Fekete A,Banki NF,Szebeni B,Vannay A,Szabo AJ,Tulassay T,Reusz GS

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Prolonged hypoglycemia leads to brain injury, despite treatment with 10% dextrose. Whether induction of hyperglycemia or ketonemia achieves better neuroprotection is unknown. Hyperglycemia is neuroprotective in other brain injuries during development; however, it worsens hypoglycemia-induced injury in the ad...

journal_title：Pediatric research

authors： Ennis K,Dotterman H,Stein A,Rao R

更新日期：2015-01-01 00:00:00

abstract：:A four-year-old Israeli Arab boy was found to have glycogen accumulation in both liver and muscle without clinical symptoms. Liver phosphorylase kinase (PK) activity was 20% of normal, resulting in undetectable activity of phosphorylase a. Muscle PK activity was about 25% of normal, resulting in a marked decrease of p...

journal_title：Pediatric research

authors： Bashan N,Iancu TC,Lerner A,Fraser D,Potashnik R,Moses SW

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Genotyping tests were developed to attenuate the impact of viral resistance. Information about the efficacy in genotype base antiretroviral therapy in children is rare and even more in low- and middle-income countries. METHODS:Sixteen children with antiretroviral therapy (ART) failure and triple-class drug-...

journal_title：Pediatric research

authors： Huerta-García G,Vazquez-Rosales JG,Mata-Marín JA,Peregrino-Bejarano L,Flores-Ruiz E,Solórzano-Santos F

更新日期：2016-07-01 00:00:00

abstract：:Localized proton magnetic resonance spectra were recorded from human cerebellum in vivo with a 1.5-T magnet. The spectra from healthy adults and preterm and term babies showed resonances from N-acetylaspartate, creatine and phosphocreatine, choline-containing compounds such as phosphocholine and glycerophosphocholine,...

journal_title：Pediatric research

authors： Hüppi PS,Posse S,Lazeyras F,Burri R,Bossi E,Herschkowitz N

更新日期：1991-12-01 00:00:00

abstract：UNLABELLED:The hGH response to an ornithin or an insulin test was measured in 105 children from 11-18 yr old with delay of growth more than 2 SD. Besides 74 subjects with normal values and 7 with complete lack of response, 24 subjects exhibited a partial rise of GH. Most of the latter had decreasing growth rate and no ...

journal_title：Pediatric research

authors： Gourmelen M,Pham-Huu-Trung MT,Girard F

更新日期：1979-04-01 00:00:00

abstract：:There is increasing evidence that cortisol contributes to cardiovascular risk. It is unclear whether physiological concentrations of serum cortisol are related to vascular risk markers in children. The cross-sectional associations between morning serum cortisol and cardiovascular risk markers: blood pressure (BP) and ...

journal_title：Pediatric research

authors： Soriano-Rodríguez P,Osiniri I,Grau-Cabrera P,Riera-Pérez E,Prats-Puig A,Carbonell-Alferez M,Schneider S,Mora-Maruny C,De Zegher F,Ibánez L,Bassols J,López-Bermejo A

更新日期：2010-11-01 00:00:00

abstract：:EBV has been associated with several malignancies in humans. EBV can also infect marmoset B lymphocytes, which, as opposed to human B cells, are permissive for lytic Epstein-Barr viral replication. Mice with a severe combined immunodeficiency phenotype (SCID mice) are extremely susceptible to EBV-induced lymphomagenes...

journal_title：Pediatric research

authors： Katz BZ,Salimi B,Saini U,McNamara JG,Eisen R

更新日期：1994-10-01 00:00:00

abstract：:This study tested the hypothesis that the sexually dimorphic adrenocortical response to stress is already established before birth. Chronically instrumented late gestation pregnant sheep carrying 16 male and 15 female age-matched singleton fetuses were subjected to an acute episode of hypoxic stress. Maternal and feta...

journal_title：Pediatric research

authors： Giussani DA,Fletcher AJ,Gardner DS

更新日期：2011-02-01 00:00:00

abstract：:Taurine is an essential amino acid during fetal life and appears to be vital for the growth of the fetus and for the development of the CNS. In intrauterine growth restriction (IUGR), fetal plasma concentrations of taurine are reduced, and we tested the hypothesis that this is caused by altered placental transport of ...

journal_title：Pediatric research

authors： Norberg S,Powell TL,Jansson T

更新日期：1998-08-01 00:00:00

abstract：:Several hours after an hypoxic-ischemic injury to the developing brain, hyperemia, then seizures, edema, and infarction can develop. The roles of nitric oxide (NO) synthesis and excitotoxin accumulation during these later phases of injury are not known. The time course of extracellular levels of amino acids within the...

journal_title：Pediatric research

authors： Tan WK,Williams CE,During MJ,Mallard CE,Gunning MI,Gunn AJ,Gluckman PD

更新日期：1996-05-01 00:00:00

abstract：:GH insensitivity may be an inherited condition or may arise as a consequence of disease of malnutrition. Laron syndrome is the most severe form of GH insensitivity, arising from an absent or defective GH receptor. Less severe forms of GH insensitivity, however, may exist, resulting in short stature but in few other fe...

journal_title：Pediatric research

authors： Thalange NK,Price DA,Gill MS,Whatmore AJ,Addison GM,Clayton PE

更新日期：1996-05-01 00:00:00

abstract：:Ambient oxygen concentration and vascular endothelial growth factor (VEGF)-A are vital in lung development. Since hypoxia stimulates VEGF-A production and hyperoxia reduces it, we hypothesized that VEGF-A down-regulation by exposure of airways to hyperoxia may result in abnormal lung development. An established model ...

journal_title：Pediatric research

authors： Esquibies AE,Bazzy-Asaad A,Ghassemi F,Nishio H,Karihaloo A,Cantley LG

更新日期：2008-01-01 00:00:00