Abstract:
:Objective This study evaluated the concept of percutaneous closure of insufficient veins using the VeinScrew principle. Methods The VeinScrew is designed to place a spring-shaped implant that contracts and clamps around the vein. The ability of the device to occlude adequately was tested in a bench model experiment. The feasibility of accurate placement and adequate venous occlusion was evaluated in an animal experiment and in a human cadaveric experiment. Results The VeinScrew implant occluded up to a pressure of 135 mmHg. In vivo studies confirmed that deployment was challenging but technically feasible, and subsequent phlebography showed closure of the vein. The cadaveric study showed that percutaneous placement of the evolved VeinScrew around the great saphenous vein was feasible and accurate. Conclusions The current studies show the feasibility of the VeinScrew concept. Future developments and translational studies are necessary to determine the potential of this technique as a new option in the phlebologist's toolbox.
journal_name
Vascularjournal_title
Vascularauthors
Boersma D,de Borst GJ,Moll FLdoi
10.1177/1708538116644117subject
Has Abstractpub_date
2017-02-01 00:00:00pages
105-109issue
1eissn
1708-5381issn
1708-539Xpii
1708538116644117journal_volume
25pub_type
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