Efflux Pump Blockers in Gram-Negative Bacteria: The New Generation of Hydantoin Based-Modulators to Improve Antibiotic Activity.

abstract：:Oncolytic viruses (OVs) induce antitumor effect by both direct lysis of target cells and eliciting immunogenic response to the virus and ultimately to the target cells. These viruses are usually natural human pathogens. Bacteriophages are natural pathogens of bacteria that do not infect human and have greater advantag...

journal_title：Frontiers in microbiology

authors： Hwang YJ,Myung H

更新日期：2020-09-24 00:00:00

abstract：:The worldwide dissemination of carbapenemase-producing Enterobacteriaceae (CPE) has become a major therapeutic concern in clinical settings. Enterobacter cloacae is a major pathogen that causes serious hospital-acquired infections. We investigated the clinical characteristics and molecular mechanisms of the first IMP-...

journal_title：Frontiers in microbiology

authors： Lee JH,Bae IK,Lee CH,Jeong S

更新日期：2017-11-28 00:00:00

abstract：:Mycobacteria are unique in many aspects of their biology. The development of genetic tools to identify genes critical for their growth by forward genetic analysis holds great promises to advance our understanding of their cellular, physiological and biochemical processes. Here we report the development of a novel tran...

journal_title：Frontiers in microbiology

authors： Riggs-Shute SD,Falkinham JO,Yang Z

更新日期：2020-01-21 00:00:00

abstract：:Rice is a major staple food across the globe. Its growth and productivity is highly dependent on the rhizobiome where crosstalk takes place between plant and the microbial community. Such interactions lead to selective enrichment of plant beneficial microbes which ultimately defines the crop health and productivity. I...

journal_title：Frontiers in microbiology

authors： Imchen M,Kumavath R,Vaz ABM,Góes-Neto A,Barh D,Ghosh P,Kozyrovska N,Podolich O,Azevedo V

更新日期：2019-09-20 00:00:00

abstract：:Low moisture content ready-to-eat foods vended in Nigerian markets could be pre-packaged or packaged at point of sale. These foods are widely and frequently consumed across Nigeria as quick foods. Despite their importance in the daily diets of Nigerians, a comprehensive study on the diversity of fungi, fungal metaboli...

journal_title：Frontiers in microbiology

authors： Ezekiel CN,Oyedele OA,Kraak B,Ayeni KI,Sulyok M,Houbraken J,Krska R

更新日期：2020-04-09 00:00:00

abstract：:Ecological understandings of soil bacterial community succession and assembly mechanism along elevational gradients in mountains remain not well understood. Here, by employing the high-throughput sequencing technique, we systematically examined soil bacterial diversity patterns, the driving factors, and community asse...

journal_title：Frontiers in microbiology

authors： Li J,Shen Z,Li C,Kou Y,Wang Y,Tu B,Zhang S,Li X

更新日期：2018-03-27 00:00:00

abstract：:PP2A-like phosphatases share high homology with PP2A enzymes and are composed of a catalytic subunit and a regulatory subunit. In Candida albicans, the PP2A-like catalytic subunit SIT4 regulates cell growth, morphogenesis, and virulence. However, the functions of its regulatory subunits remain unclear. Here, by homolo...

journal_title：Frontiers in microbiology

authors： Han Q,Pan C,Wang Y,Zhao L,Wang Y,Sang J

更新日期：2019-12-20 00:00:00

abstract：:In light of public concerns over the use of pesticides and antibiotics in plant protection and the subsequent selection for spread of resistant bacteria in the environment, it is inevitable to broaden our knowledge about viable alternatives, such as natural antagonists and their mode of action. The genus Pseudomonas i...

journal_title：Frontiers in microbiology

authors： Zengerer V,Schmid M,Bieri M,Müller DC,Remus-Emsermann MNP,Ahrens CH,Pelludat C

更新日期：2018-02-09 00:00:00

abstract：:The competition between sulfate reducing bacteria and methanogens over common substrates has been proposed as a critical control for methane production. In this study, we examined the co-existence of methanogenesis and sulfate reduction with shared substrates over a large range of sulfate concentrations and rates of s...

journal_title：Frontiers in microbiology

authors： Sela-Adler M,Ronen Z,Herut B,Antler G,Vigderovich H,Eckert W,Sivan O

更新日期：2017-05-05 00:00:00

abstract：:Adaptation to changes in osmolarity is fundamental for the survival of living cells, and has implications in food and industrial biotechnology. It has been extensively studied in the yeast Saccharomyces cerevisiae, where the Hog1 stress activated protein kinase was discovered about 20 years ago. Hog1 is the core of th...

journal_title：Frontiers in microbiology

authors： Gonzalez R,Morales P,Tronchoni J,Cordero-Bueso G,Vaudano E,Quirós M,Novo M,Torres-Pérez R,Valero E

更新日期：2016-09-28 00:00:00

abstract：:Little is known about the importance and/or mechanisms of biological mineral oxidation in sediments, partially due to the difficulties associated with culturing mineral-oxidizing microbes. We demonstrate that electrochemical enrichment is a feasible approach for isolation of microbes capable of gaining electrons from ...

journal_title：Frontiers in microbiology

authors： Rowe AR,Chellamuthu P,Lam B,Okamoto A,Nealson KH

更新日期：2015-01-14 00:00:00

abstract：:We report the isolation, characterization, and development of a robust genetic system for a halophilic, Fe(II)-oxidizing bacterium isolated from a vertical borehole originating 714 m below the surface located in the Soudan Iron Mine in northern Minnesota, USA. Sequence analysis of the 16S rRNA gene places the isolate ...

journal_title：Frontiers in microbiology

authors： Bonis BM,Gralnick JA

更新日期：2015-07-16 00:00:00

abstract：:Gliding motility facilitates the movement of bacteria along surfaces in many Bacteroidetes species and results in spreading colonies. The adhesins required for the gliding are secreted through a gliding motility-associated protein secretion system, known as the type IX secretion system (T9SS). The fish pathogen Flavob...

journal_title：Frontiers in microbiology

authors： Penttinen R,Hoikkala V,Sundberg LR

更新日期：2018-03-26 00:00:00

abstract：:Cheese microbiota contribute significantly to the final characteristics of cheeses due to the growth and interaction between cheese microorganisms during processing and ripening. For raw milk cheeses, such as Parmigiano Reggiano (PR), the microbiota derive from the raw milk itself, the dairy environment, and the start...

journal_title：Frontiers in microbiology

authors： Bottari B,Levante A,Bancalari E,Sforza S,Bottesini C,Prandi B,De Filippis F,Ercolini D,Nocetti M,Gatti M

更新日期：2020-10-02 00:00:00

abstract：:The wide spread of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae is great threat to public health in China. Plasmids are among the major factors mediating blaKPC gene dissemination. A total of 156 carbapenem-resistant Enterobacteriaceae (CRE) isolates were identified in a tertiary hospital in ...

journal_title：Frontiers in microbiology

authors： Huang J,Ding H,Shi Y,Zhao Y,Hu X,Ren J,Huang G,Wu R,Zhao Z

更新日期：2018-08-21 00:00:00

abstract：:Type IV secretion systems (T4SSs) play a central role in the pathogenicity of many important pathogens, including Agrobacterium tumefaciens, Helicobacter pylori, and Legionella pneumophila. The T4SSs are related to bacterial conjugation systems, and are classified into two subgroups, type IVA (T4ASS) and type IVB (T4B...

journal_title：Frontiers in microbiology

authors： Nagai H,Kubori T

更新日期：2011-06-27 00:00:00

abstract：:Klebsiella pneumoniae is an important nosocomial pathogen with an extraordinary resistant phenotype due to a combination of acquired resistant-elements and efflux mechanisms. In this study a detailed molecular characterization of 11 K. pneumoniae isolates of clinical origin was carried out. Eleven clinical isolates we...

journal_title：Frontiers in microbiology

authors： Anes J,Hurley D,Martins M,Fanning S

更新日期：2017-10-23 00:00:00

abstract：:We explore the potential of bacterial secretion systems as tools for genomic modification of human cells. We previously showed that foreign DNA can be introduced into human cells through the Type IV A secretion system of the human pathogen Bartonella henselae. Moreover, the DNA is delivered covalently attached to the ...

journal_title：Frontiers in microbiology

authors： Guzmán-Herrador DL,Steiner S,Alperi A,González-Prieto C,Roy CR,Llosa M

更新日期：2017-08-22 00:00:00

abstract：:The objective of this study was to investigate the ability of a culture highly enriched with the polyphosphate-accumulating organism, "Candidatus Accumulibacter phosphatis" clade IIC, to adjust their metabolism to different phosphate availabilities. For this purpose the biomass was cultivated in a sequencing batch rea...

journal_title：Frontiers in microbiology

authors： Welles L,Abbas B,Sorokin DY,Lopez-Vazquez CM,Hooijmans CM,van Loosdrecht MC,Brdjanovic D

更新日期：2017-01-05 00:00:00

abstract：:Lactic acid bacteria (LAB) are Gram positive bacteria widely used in the production of fermented food in particular cheese and yoghurts. Bacteriophage infections during fermentation processes have been for many years a major industrial concern and have stimulated numerous research efforts. Better understanding of the ...

journal_title：Frontiers in microbiology

authors： Chapot-Chartier MP

更新日期：2014-05-22 00:00:00

abstract：:Generally, plants are not considered as hosts for human and animal pathogens (HAP). The recent produce-associated outbreaks of food-borne diseases have drawn attention toward significant deficiencies in our understanding of the ecology of HAP, and their potential for interkingdom transfer. To examine the association o...

journal_title：Frontiers in microbiology

authors： Yousaf S,Bulgari D,Bergna A,Pancher M,Quaglino F,Casati P,Campisano A

更新日期：2014-07-08 00:00:00

abstract：:The incidence of non-alcoholic fatty liver disease (NAFLD) is rising annually, and emerging evidence suggests that the gut bacteria plays a causal role in NAFLD. Naringin, a natural flavanone enriched in citrus fruits, is reported to reduce hepatic lipid accumulation, but to date, no investigations have examined wheth...

journal_title：Frontiers in microbiology

authors： Mu H,Zhou Q,Yang R,Zeng J,Li X,Zhang R,Tang W,Li H,Wang S,Shen T,Huang X,Dou L,Dong J

更新日期：2020-11-13 00:00:00

abstract：:In 2006 several yeast-like fungi were isolated from apples that showed a postharvest disorder named "white haze." These strains were morphologically and molecularly assigned to the genus Tilletiopsis. Following the recent reclassification of yeasts in Ustilaginomycotina and the genus Tilletiopsis in particular, specie...

journal_title：Frontiers in microbiology

authors： Richter C,Yurkov AM,Boekhout T,Stadler M

更新日期：2019-11-22 00:00:00

abstract：:With the increasing amount of evidence linking certain disorders of the human body to a disturbed gut microbiota, there is a growing interest for compounds that positively influence its composition and activity through diet. Besides the consumption of probiotics to stimulate favorable bacterial communities in the huma...

journal_title：Frontiers in microbiology

authors： Rivière A,Selak M,Lantin D,Leroy F,De Vuyst L

更新日期：2016-06-28 00:00:00

abstract：:Many bacterial pathogens use quorum-sensing (QS) signaling to regulate the expression of factors contributing to virulence and persistence. Bacteria produce signals of different chemical classes. The signal molecule, known as diffusible signal factor (DSF), is a cis-unsaturated fatty acid that was first described in t...

journal_title：Frontiers in microbiology

authors： Rahmani-Badi A,Sepehr S,Fallahi H,Heidari-Keshel S

更新日期：2015-04-28 00:00:00

abstract：:Histone-like nucleoid structuring protein (H-NS) in enterobacteria plays an important role in facilitating chromosome organization and functions as a crucial transcriptional regulator for global gene regulation. Here, we presented an observation that H-NS of Salmonella enterica serovar Typhimurium could undergo protei...

journal_title：Frontiers in microbiology

authors： Hu L,Kong W,Yang D,Han Q,Guo L,Shi Y

更新日期：2019-07-03 00:00:00

abstract：:Currently, the most utilized antimicrobial in processing facilities is peracetic acid, PAA; however, this chemical is increasingly recognized as a hazard to human health. Preliminary evidence suggests that ozone, when introduced in a specific manner, can reduce the noxious nature of PAA. Therefore, the objective of th...

journal_title：Frontiers in microbiology

authors： Dittoe DK,Feye KM,Peyton B,Worlie D,Draper MJ,Ricke SC

更新日期：2019-01-08 00:00:00

abstract：:Corynebacterium glutamicum is a commonly applied host for the industrial production of amino acids. While valued for its robustness, it is somewhat inferior to competing strains such as Escherichia coli because of the relatively low growth rate of 0.40 h-1 in synthetic, industrial media. Accordingly, adaptive laborato...

journal_title：Frontiers in microbiology

authors： Graf M,Haas T,Müller F,Buchmann A,Harm-Bekbenbetova J,Freund A,Nieß A,Persicke M,Kalinowski J,Blombach B,Takors R

更新日期：2019-08-06 00:00:00

abstract：:Fungi are prominent components of most terrestrial ecosystems, both in terms of biomass and ecosystem functioning, but the hyper-diverse nature of most communities has obscured the search for unifying principles governing community organization. In particular, unlike plants and animals, observational studies provide l...

journal_title：Frontiers in microbiology

authors： Crowther TW,Maynard DS,Crowther TR,Peccia J,Smith JR,Bradford MA

更新日期：2014-10-31 00:00:00

abstract：:Inhalation of Yersinia pestis can lead to pneumonic plague, which without treatment is inevitably fatal. Two novel formulations of liposome-encapsulated ciprofloxacin, 'ciprofloxacin for inhalation' (CFI, Lipoquin®) and 'dual release ciprofloxacin for inhalation' (DRCFI, Pulmaquin®) containing CFI and ciprofloxacin so...

journal_title：Frontiers in microbiology

authors： Hamblin KA,Armstrong SJ,Barnes KB,Davies C,Laws T,Blanchard JD,Harding SV,Atkins HS

更新日期：2017-02-06 00:00:00