Abstract:
:Small teleost fish including zebrafish and medaka have been used as animal models in basic science research due to the relative ease of handling and transparency during embryogenesis. Current advances in genetic engineering and progress in disease genetics allowed utilization of these fish to study neurological diseases and psychiatric disorders. This review summarizes the advantages and disadvantages of using fish for neuropsychiatric research using primarily our own studies as examples. We discuss how fish belong to a class of vertebrates, are feasible for imaging, and include diverse species with multiple research possibilities yet to be discovered.
journal_name
Neurosci Resjournal_title
Neuroscience researchauthors
Matsui Hdoi
10.1016/j.neures.2017.02.004subject
Has Abstractpub_date
2017-07-01 00:00:00pages
1-7eissn
0168-0102issn
1872-8111pii
S0168-0102(16)30231-0journal_volume
120pub_type
杂志文章,评审abstract::Many studies on long-term potentiation (LTP) in hippocampal region CA1 focus on receptor-mediated events that are often presumed to be linked to postsynaptic processes. Whereas it is now well-known that LTP consists of multiple components involving increases in postsynaptic responsiveness as well as enhanced presynapt...
journal_title:Neuroscience research
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pub_type: 杂志文章
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journal_title:Neuroscience research
pub_type: 杂志文章
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journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2017.10.002
更新日期:2018-08-01 00:00:00
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journal_title:Neuroscience research
pub_type: 杂志文章,评审
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doi:10.1016/j.neures.2013.10.006
更新日期:2014-02-01 00:00:00
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journal_title:Neuroscience research
pub_type: 杂志文章
doi:10.1016/j.neures.2007.05.005
更新日期:2007-09-01 00:00:00
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pub_type: 杂志文章,评审
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