Abstract:
:Mortality rate from bladder cancer in Europe is the highest in its Central Region. This study is an attempt to find underlying factors by proper characterisation of large cohort of Polish patients with bladder cancer.This is a multicentre study enrolling 1360 consecutive patients diagnosed with primary urothelial carcinoma of the bladder in years 2012-2013 in Poland. All patients underwent transurethral resection of the bladder tumor. Data on staging and grading of all cancers were collected, as well as several demographic and clinical factors were tested for the association with muscle invasiveness of the cancer.Mean age of the cohort was 69.6 years, male to female ratio was 3:1. Bladder cancer stage Ta, T1 and muscle-invasive (MIBC) was diagnosed in 533 (39.2%), 516 (37.9%) and 296 (21.8%) patients, respectively. Patients with MIBC were older (73 vs. 68 years, p<0.05), had lower body mass index (25.4 vs. 26.5 kg/m2, p<0.05), lower haemoglobin concentration (12.2 vs. 13.4 mg/l, p<0.05), longer history of haematuria (86.2 vs. 74.4 days) and longer time interval from first symptom to diagnosis (118.0 vs. 88.2 days), compared to patients with Ta and T1 tumors.High mortality rate from bladder cancer in Central Europe can result from very high incidence of high-risk T1 tumors and high prevalence of prognostic factors of poor survival.
journal_name
Neoplasmajournal_title
Neoplasmaauthors
Poletajew S,Biernacki R,Buraczynski P,Chojnacki J,Czarniecki S,Gajewska D,Pohaba T,Sondka J,Skrzypczyk M,Suchojad T,Wojtkowiak D,Zaforemski B,Zapala L,Zemla A,Radziszewski Pdoi
10.4149/neo_2016_420subject
Has Abstractpub_date
2016-01-01 00:00:00pages
642-7issue
4eissn
0028-2685issn
1338-4317journal_volume
63pub_type
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