Stage of bladder cancer in Central Europe - Polish perspective.

Abstract:

:Mortality rate from bladder cancer in Europe is the highest in its Central Region. This study is an attempt to find underlying factors by proper characterisation of large cohort of Polish patients with bladder cancer.This is a multicentre study enrolling 1360 consecutive patients diagnosed with primary urothelial carcinoma of the bladder in years 2012-2013 in Poland. All patients underwent transurethral resection of the bladder tumor. Data on staging and grading of all cancers were collected, as well as several demographic and clinical factors were tested for the association with muscle invasiveness of the cancer.Mean age of the cohort was 69.6 years, male to female ratio was 3:1. Bladder cancer stage Ta, T1 and muscle-invasive (MIBC) was diagnosed in 533 (39.2%), 516 (37.9%) and 296 (21.8%) patients, respectively. Patients with MIBC were older (73 vs. 68 years, p<0.05), had lower body mass index (25.4 vs. 26.5 kg/m2, p<0.05), lower haemoglobin concentration (12.2 vs. 13.4 mg/l, p<0.05), longer history of haematuria (86.2 vs. 74.4 days) and longer time interval from first symptom to diagnosis (118.0 vs. 88.2 days), compared to patients with Ta and T1 tumors.High mortality rate from bladder cancer in Central Europe can result from very high incidence of high-risk T1 tumors and high prevalence of prognostic factors of poor survival.

journal_name

Neoplasma

journal_title

Neoplasma

authors

Poletajew S,Biernacki R,Buraczynski P,Chojnacki J,Czarniecki S,Gajewska D,Pohaba T,Sondka J,Skrzypczyk M,Suchojad T,Wojtkowiak D,Zaforemski B,Zapala L,Zemla A,Radziszewski P

doi

10.4149/neo_2016_420

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

642-7

issue

4

eissn

0028-2685

issn

1338-4317

journal_volume

63

pub_type

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