Trace elements in children suffering from sickle cell anemia: A case-control study.

abstract：:Second- and higher-order degradation reactions sometimes cannot be approximated with linear or exponential relationships and need to be appropriately modeled. Events above the COULTER HmX Analyzer white blood cell (WBC) counting threshold were recorded for the HmX PAK reagent system stored at five elevated temperature...

journal_title：Journal of clinical laboratory analysis

authors： Magari RT,Murphy KP,Fernandez T

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Ursodeoxycholic acid (UDCA) has been widely recommended as the first-line drug for primary biliary cholangitis (PBC) in the current guidelines. However, its therapeutic effects are poor in nearly one-third of patients. The early identification and intervention of these patients is crucial for delaying diseas...

journal_title：Journal of clinical laboratory analysis

authors： Tian S,Liu Y,Sun K,Zhou X,Ma S,Zhang M,Zhou X,Wang L,Han Y

更新日期：2020-11-01 00:00:00

abstract：:The use of serum alkaline phosphatase (ALP) isoenzymes as markers of breast cancer metastases and treatment efficacy has received little attention. Twenty-six breast cancer women (56+/-13 years, all post-menopausal) were prospectively evaluated during their first and third course of chemotherapy (4-week interval). Ser...

journal_title：Journal of clinical laboratory analysis

authors： Le Bricon T,Gay-Bellile C,Cottu P,Benlakehal M,Guillon H,Houzé P

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Previous studies suggested that adiponectin (APN) could ameliorate ischemia/reperfusion injury and endothelial dysfunction in patients with acute myocardial infarction. However, the relationship between serum APN level and coronary flow after primary percutaneous coronary intervention (PPCI) in patients with...

journal_title：Journal of clinical laboratory analysis

authors： Liang S,Li H,Shen X,Liu R

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The aim of our study was to assess two tumor markers, carbohydrate antigen 724 (CA724) and neuron-specific enolase (NSE), in 20 healthy individuals. Then, we determined their average intra- and inter-individual biological variations (CVI and CVG ). METHODS:Blood samples were taken at weekly intervals for fi...

journal_title：Journal of clinical laboratory analysis

authors： Wang S,Zhao M,Mu R,Zhang X,Yun K,Shang H

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Recently, several studies have investigated the relationship between Pre-miR-27a rs895819 polymorphism and risk of various cancers. However, the relationship between rs895819 and diffuse large B-cell lymphoma (DLBCL) has not been well known. METHODS:In this study, we conducted a case-control study to explor...

journal_title：Journal of clinical laboratory analysis

authors： Tang W,Xu H,Ma D,Ma R,Wu J,Yu X,Feng J,Liu Q

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:To explore relationships between immunological status, clinical features, radiographic damage, disease activity, and functional disability in Tunisian patients with rheumatoid arthritis (RA). MATERIALS AND METHODS:The study was carried out in 112 patients with RA. Demographic characteristics, disease duratio...

journal_title：Journal of clinical laboratory analysis

authors： Hamad MB,Marzouk S,Kaddour N,Masmoudi H,Fakhfakh F,Rebai A,Bahloul Z,Maalej A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The performance of 18 routine chemical detection methods was evaluated by the sigma (σ) metric, and Westgard Sigma rules with run size were used to establish internal quality control (IQC) standards to reduce patient risks. MATERIALS AND METHODS:External quality assessment (EQA) and internal quality control...

journal_title：Journal of clinical laboratory analysis

authors： Peng S,Zhang J,Zhou W,Mao W,Han Z

更新日期：2020-12-03 00:00:00

abstract：OBJECTIVE:Sex-determining region Y-box 30 (SOX30) suppresses progression of several cancers, whereas its role in breast cancer is unclear. Therefore, we aimed to determine the correlation of SOX30 with tumor characteristics and prognosis in breast cancer patients. METHODS:The tumor samples of 510 breast cancer patient...

journal_title：Journal of clinical laboratory analysis

authors： Peng H,Luo Y,Wu J,Yin W

更新日期：2020-06-01 00:00:00

abstract：:Rats exposed to constant light develop polycystic ovarian (PCO) disease with persistent estrus, representing an estrogen-dominant condition. Herein, we report that fluctuations seen in the vaginal microflora in cyclic rats were not observed in PCO rats with persistent estrus. The vaginal-cervical mucosa of PCO rats sh...

journal_title：Journal of clinical laboratory analysis

authors： Singh KB,Mahajan DK,Tewari RP

更新日期：1996-01-01 00:00:00

abstract：:An immunoenzymometric assay (IEMA) for a new CA125-like antigen, CA602, was developed. Five monoclonal antibodies raised against a human ovarian carcinoma cell line could detect their respective antigens in the sera of ovarian carcinoma patients. The antigen levels detected in serum by the various antibodies correlate...

journal_title：Journal of clinical laboratory analysis

authors： Mochizuki H,Sato I,Nagoya K,Furusako S,Yamauchi T,Masuko H,Sato H,Morishita H,Yajima M,Sasaki H

更新日期：1992-01-01 00:00:00

abstract：:C-peptide is secreted in equimolar concentrations with insulin, and is often measured to assess pancreatic beta-cell function. C-peptide analysis is most often performed by radioimmunoassay (RIA) which has several disadvantages. We evaluated an automated, chemiluminescent immunoassay for C-peptide in terms of precisio...

journal_title：Journal of clinical laboratory analysis

authors： Hardy RW,Cohn M,Konrad RJ

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Acute respiratory distress syndrome (ARDS) is a critical condition characterized by bilateral pulmonary infiltrates and severe hypoxemia. This study aimed to evaluate the diagnostic and prognostic values of Club cell protein 16 (CC16) in critical care patients with ARDS. METHODS:In this retrospective observ...

journal_title：Journal of clinical laboratory analysis

authors： Lin J,Zhang W,Wang L,Tian F

更新日期：2018-02-01 00:00:00

abstract：:The detection of hepatitis C virus (HCV) RNA by nucleic acid amplification techniques is the method of choice to differentiate between ongoing and past infection, and can be used to monitor the course of HCV infection. In this study, we evaluated the performance characteristics of a newly developed transcription-media...

journal_title：Journal of clinical laboratory analysis

authors： Ross RS,Viazov SO,Hoffmann S,Roggendorf M

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Identification of biomarkers for acute myeloid leukemia (AML) is important for treating this malignancy. Recent studies have reported that microRNAs (miRNAs) are stably detectable in the blood/plasma and can be used as biomarkers for various types of cancer including AML. The aim of this study was to analyze...

journal_title：Journal of clinical laboratory analysis

authors： Yu G,Yin Z,He H,Zheng Z,Chai Y,Xuan L,Lin R,Wang Q,Li J,Xu D

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:This study was to investigate the changes of antifungal susceptibilities caused by the phenotypic switching in patients with vulvovaginal candidiasis (VVC). METHODS:229 women were enrolled in this study. The vaginal smears of these patients were collected and gram stained for fungal microscopic observation. ...

journal_title：Journal of clinical laboratory analysis

authors： Tang Y,Yu F,Huang L,Hu Z

更新日期：2019-01-01 00:00:00

abstract：:Previously, an ultrasensitive enzyme immunoassay (immune complex transfer enzyme immunoassay) for p24 antigen of HIV-1 was developed. The immune complex comprising 2,4-dinitrophenyl-biotinyl-bovine serum albumin-rabbit anti-p24 Fab' conjugate, p24 antigen, and rabbit anti-p24 Fab' -beta-D-galactosidase conjugate was t...

journal_title：Journal of clinical laboratory analysis

authors： Hashida S,Hashinaka K,Nishikata I,Saito A,Takamizawa A,Shinagawa H,Ishikawa E

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:The primary test for the laboratory confirmation of measles is immunoglobulin M (IgM) serology. It is therefore important to evaluate new commercial measles IgM immunoassays to ensure high-quality measles diagnostic testing. The purpose of this study was to evaluate the diagnostic performance of LIAISON IgM ...

journal_title：Journal of clinical laboratory analysis

authors： Sampedro A,Rodríguez-Granger J,Gómez C,Lara A,Gutierrez J,Otero A

更新日期：2013-11-01 00:00:00

abstract：:Interleukin (IL)-6 and IL-8 were measured in 101 serum samples collected from eight intensive-care unit patients using a polystyrene-based stick enzyme-linked immunosorbent assay (STICKELISA) system. This system consisted of an immobilized-antibody ELISA stick and a noncontact spectrophotometer. Cytokine concentration...

journal_title：Journal of clinical laboratory analysis

authors： Miwa K,Shibayama N,Moriguchi T,Goto J,Yanagisawa M,Yamazaki Y,Jung G,Matsuda K

更新日期：2009-01-01 00:00:00

abstract：:Epithelial cells are typically connected through different types of cell junctions that are localized from the apical membrane to the basal surface. In this way, epithelium cells form the first barrier against pathogenic microorganisms and prevent their entry into internal organs and the circulatory system. Recent stu...

journal_title：Journal of clinical laboratory analysis

authors： Zheng M,Sun S,Zhou J,Liu M

更新日期：2020-10-17 00:00:00

abstract：:One of the most significant achievements of the biochemist during the past two decades is the use to which immunologically based assays have been put in clinical diagnosis (Hood et al.: Immunology, 1984). The problem faced and surmounted by immunologists in effecting the transition from research tool to routine clinic...

journal_title：Journal of clinical laboratory analysis

authors： Nicholls PJ,Malcolm AD

更新日期：1989-01-01 00:00:00

abstract：:Quantitation of hemoglobin alpha 2 delta 2 (HbA2) is a basic and confirmatory test in diagnosing the carrier state of beta-thalassemia. The present study was designed to investigate the effect of cigarette smoking on the diagnostic reliability of HbA2. A total of 2,867 (654 smokers and 2,213 never smokers) male subjec...

journal_title：Journal of clinical laboratory analysis

authors： Tarazi IS,Sirdah MM,El Jeadi H,Al Haddad RM

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that dysfunctional regulatory T cells (Tregs) may be associated with Graves' disease (GD). In this study, we evaluated four serum Treg-associated miRNAs (miR-210, miR-182, miR-155, and miR-146a) expressions and assessed the potential of serum miRNAs as biomarkers of GD. ME...

journal_title：Journal of clinical laboratory analysis

authors： Zheng L,Zhuang C,Wang X,Ming L

更新日期：2018-02-01 00:00:00

abstract：:We here describe an ion-exchange high-performance liquid chromatography technique with electrochemical detection for rapid quantification of glutathione, homocysteine, cysteinylglycine, and methionine. The analytical validation of the technique showed within-assay and between-assay coefficients of variation between 3....

journal_title：Journal of clinical laboratory analysis

authors： Houze P,Gamra S,Madelaine I,Bousquet B,Gourmel B

更新日期：2001-01-01 00:00:00

abstract：:A method that could be facilitated for the quantitation and qualitation of gangliosides in human plasma was developed and applied in the present study for characterization of ganglioside patterns in plasmas of patients with neoplastic diseases including gastric cancer, adult T-cell leukemia (ATL), and acute lymphocyti...

journal_title：Journal of clinical laboratory analysis

authors： Ayabe M,Shichijo S,Yokoyama MM

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:To determine the metabolic characteristics of patients with colon cancer (CC) and rectal cancer (RC) using gas chromatography-mass spectrometry (GC-MS)-based metabolomics. METHODS:In this study, serum samples were collected from 22 CC patients and 23 RC patients preoperatively and postoperatively and 45 hea...

journal_title：Journal of clinical laboratory analysis

authors： Wu J,Wu M,Wu Q

更新日期：2020-08-01 00:00:00

abstract：:Mycobacterium tuberculosis bacilli are seldom demonstrated in tuberculous pleural effusion (TPE) by conventional bacteriological methods. In this study, an indirect enzyme-linked immunosorbent assay (ELISA) was developed to detect IgG against four mycobacterial recombinant antigens (ESAT-6, PlcA, HspX and Tb8.4) in 69...

journal_title：Journal of clinical laboratory analysis

authors： Sumi S,Radhakrishnan VV

更新日期：2010-01-01 00:00:00

abstract：:Candida dubliniensis is a recently described pathogenic species which shares many phenotypic features with Candida albicans and therefore, may be misidentified in microbiological laboratories. Because molecular methods can be onerous and unfeasible in routine mycological laboratories with restricted budgets such as th...

journal_title：Journal of clinical laboratory analysis

authors： de Loreto ES,Pozzatti P,Alves Scheid L,Santurio D,Morais Santurio J,Alves SH

更新日期：2008-01-01 00:00:00

abstract：:N-terminal pro-brain natriuretic peptide (NT-proBNP) and BNP measurement could have a significant role in differentiating dyspnea between cardiac or pulmonary origin in the emergency room. The development of new and different commercial assays for these B-type natriuretic peptides offers the possibility of improving a...

journal_title：Journal of clinical laboratory analysis

authors： Sanz MP,Borque L,Rus A,Vicente B,Ramírez Y,Lasa L

更新日期：2006-01-01 00:00:00

abstract：:Numerous detection methods for Helicobacter Pylori (H. pylori) have been developed with varying degrees of purported diagnostic utility. We have developed a rapid nonradioactive in situ hybridization (ISH) method for H. pylori detection in paraffin-embedded tissue and assessed its relative diagnostic performance by re...

journal_title：Journal of clinical laboratory analysis

authors： Barrett DM,Faigel DO,Metz DC,Montone K,Furth EE

更新日期：1997-01-01 00:00:00