Abstract:
:The ability to maintain and expand the pool of adipocytes in adults is integral to the regulation of energy balance, tissue/stem cell homeostasis, and disease pathogenesis. For decades, our knowledge of adipocyte precursors has relied on cellular models. The identity of native adipocyte precursors has remained unclear. Recent studies have identified distinct adipocyte precursor populations that are physiologically regulated and contribute to the development, maintenance, and expansion of adipocyte pools in mice. With new tools available, the properties of adipocyte precursors can now be defined, and the regulation and function of adipose plasticity in development and physiology can be explored.
journal_name
Genes Devjournal_title
Genes & developmentauthors
Hepler C,Vishvanath L,Gupta RKdoi
10.1101/gad.293704.116subject
Has Abstractpub_date
2017-01-15 00:00:00pages
127-140issue
2eissn
0890-9369issn
1549-5477pii
31/2/127journal_volume
31pub_type
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journal_title:Genes & development
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journal_title:Genes & development
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journal_title:Genes & development
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