Abstract:
:The use of novel materials in the nano-scale size range for applications in devices, drugs and diagnostic agents comes with a number of new opportunities, and also serious challenges to human applications. The larger size of particulate-based agents, as compared to traditional drugs, allows for the significant advantages of multivalency and multi-functionality. However, the human use of nanomaterials requires a thorough understanding of the biocompatibility of the synthetic molecules and their complex pharmacology. Possible toxicities created by the unusual properties of the nanoparticles are neither well-understood, nor predictable yet. A key to the successful use of the burgeoning field of nanomaterials as diagnostic and therapeutic agents will be to appropriately match the biophysical features of the particle to the disease system to be evaluated or treated.
journal_name
Curr Opin Biotechnoljournal_title
Current opinion in biotechnologyauthors
Scheinberg DA,Grimm J,Heller DA,Stater EP,Bradbury M,McDevitt MRdoi
10.1016/j.copbio.2017.01.002subject
Has Abstractpub_date
2017-08-01 00:00:00pages
66-73eissn
0958-1669issn
1879-0429pii
S0958-1669(16)30222-1journal_volume
46pub_type
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journal_title:Current opinion in biotechnology
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journal_title:Current opinion in biotechnology
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