Diffusion limited immunochemical sensing.

Abstract:

:The time-dependent surface coverage of antigen-antibody complexes for a sensor in which antigens are bound to surface immobilized antibodies is determined analytically. Assuming a reversible first order reaction between the antigens and antibodies, a model is derived describing the dynamical response of the sensor. The surface coverage is related explicitly to the antigen concentration which is of special interest in experimental situations. The stationary state and short time behaviour are determined explicitly. Several illustrations of the full solution are provided.

journal_name

Bull Math Biol

authors

Geurts BJ

doi

10.1007/BF02460114

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

359-79

issue

3

eissn

0092-8240

issn

1522-9602

pii

S0092-8240(89)80082-5

journal_volume

51

pub_type

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