Pharmacogenetics for Safe Codeine Use in Sickle Cell Disease.

abstract：:A family is described in which the father and three (and probably all four) of his children had a decreased capacity for the oxidation of medium-chain fatty acids. One of the children suddenly died at the age of 16 months following an episode of a rapidly deteriorating Reye syndrome-like illness with hypoketotic hypog...

journal_title：Pediatrics

authors： Duran M,Hofkamp M,Rhead WJ,Saudubray JM,Wadman SK

更新日期：1986-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the duration of protection of pentavaent rotavirus vaccine (RV5) against rotavirus hospitalizations in Nicaragua, a developing country in Central America. METHODS:We conducted a case-control study at 4 hospitals from 2007 through 2010, including 1016 children hospitalized with laboratory-confirme...

journal_title：Pediatrics

authors： Patel M,Pedreira C,De Oliveira LH,Umaña J,Tate J,Lopman B,Sanchez E,Reyes M,Mercado J,Gonzalez A,Perez MC,Balmaceda A,Andrus J,Parashar U

更新日期：2012-08-01 00:00:00

abstract：:Nonfamilial cardiomyopathies in childhood have been only sporadically ascribed to endocrine disorders. We report on a 4-month-old male infant presenting with Cushing's syndrome associated with excessive body weight (8.9 kg; >97th percentile) and features of virilization (Tanner stage 2 for pubic hair development). Abd...

journal_title：Pediatrics

authors： Hauser J,Riedl S,Michel-Behnke I,Minkov M,Perneczky E,Horcher E

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:End-of-life clinical care in cystic fibrosis (CF) differs substantially from terminal care in childhood cancer. To examine this difference, we reviewed the medical care of a cohort of CF patients treated at Children's Hospital, Boston, to document the use of preventive, therapeutic, and palliative care in the...

journal_title：Pediatrics

authors： Robinson WM,Ravilly S,Berde C,Wohl ME

更新日期：1997-08-01 00:00:00

abstract：:Questionnaires were used to survey 1,435 parents and 446 physicians in order to determine and compare attitudes and beliefs about enuresis. Although both groups thought that bed-wetting is a maturational problem, the parent group thought emotional causes were important and were less likely to accept small bladder size...

journal_title：Pediatrics

authors： Shelov SP,Gundy J,Weiss JC,McIntire MS,Olness K,Staub HP,Jones DJ,Haque M,Ellerstein NS,Heagarty MC,Starfield B

更新日期：1981-05-01 00:00:00

abstract：:These are case reports of two children with structurally normal hearts and with normal coronary arteries, who survived myocardial infarction in the early neonatal period. They are only the third and fourth reported survivors of neonatal myocardial infarction and the first in which hypercholesterolemia is postulated to...

journal_title：Pediatrics

authors： Boulton J,Henry R,Roddick LG,Rogers D,Thompson L,Warner G

更新日期：1991-07-01 00:00:00

abstract：:Recent improvement in child mortality has taken place in all regions of the world. In developing countries, major remaining causes are neonatal problems, diarrheal diseases, vaccine-preventable diseases, and respiratory diseases. Foreign aid has come in many forms, among them individual persons, nongovernmental organi...

journal_title：Pediatrics

authors： Wegman ME

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between specific television-viewing habits and both sleep habits and sleep disturbances in school children. METHODS:The parents of 495 children in grades kindergarten through fourth grade in three public elementary schools completed two retrospective survey questionnaires, one...

journal_title：Pediatrics

authors： Owens J,Maxim R,McGuinn M,Nobile C,Msall M,Alario A

更新日期：1999-09-01 00:00:00

abstract：:The risk of respiratory and other illnesses in children (age groups: 6 weeks through 17 months, 18 through 35 months, and 36 through 59 months) in various types of day-care facilities was studied. Children considered exposed to day care were those who were enrolled in day care with at least one unrelated child for at ...

journal_title：Pediatrics

authors： Hurwitz ES,Gunn WJ,Pinsky PF,Schonberger LB

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To determine if high levels of somatization symptoms in 13- to 16-year-olds from the general population predict risk of major depression and other psychiatric disorders 4 years later. METHOD:Cohort study, using interview and self-report survey data from the 1983 Ontario Child Health Study (OCHS) and 1987 OCH...

journal_title：Pediatrics

authors： Zwaigenbaum L,Szatmari P,Boyle MH,Offord DR

更新日期：1999-06-01 00:00:00

abstract：:Developmental screening tests are in widespread use, but few reliable and valid tests are available. The most frequently used screening instrument for detecting young children who are at risk for developmental delays is the Denver Developmental Screening Test (DDST). Although the DDST has excellent test specificity, o...

journal_title：Pediatrics

authors： Meisels SJ

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVE:To determine clinical characteristics in children with osteogenesis imperfecta (OI) regarding impairment (range of joint motion and muscle strength) and disability (functional skills) in relation to the different types of the disease, and to study the correlation between characteristics of impairment and disa...

journal_title：Pediatrics

authors： Engelbert RH,van der Graaf Y,van Empelen R,Beemer FA,Helders PJ

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Poor mental health is recognized as one of the greatest global burdens of disease. Maternal mental health is crucial for the optimal health of mothers and their children. We examined the effects of an Australian Nurse Home Visiting (NHV) program (right@home), offered to pregnant women experiencing adversity,...

journal_title：Pediatrics

authors： Goldfeld S,Bryson H,Mensah F,Gold L,Orsini F,Perlen S,Price A,Hiscock H,Grobler A,Dakin P,Bruce T,Harris D,Kemp L

更新日期：2021-02-01 00:00:00

abstract：:This article provides background information on acoustic impedance testing and illustrates utilization of test results in pediatric clinical practice. Acoustic impedance measurement devices are presently being used successfully by hearing screening programs and by otorhinolaryngologists in clinical and hospital setti...

journal_title：Pediatrics

authors： Ehrlich MA,Tait CA

更新日期：1975-05-01 00:00:00

abstract：:Seventy-four patients with adolescent scoliosis underwent cardiac examination and M-mode echocardiography to detect the presence of mitral valve prolapse (MVP). Twenty-one (28%) had echocardiographic evidence of MVP, whereas 18 had auscultatory findings of a nonejection click or late systolic murmur. A subset of 41 pa...

journal_title：Pediatrics

authors： Hirschfeld SS,Rudner C,Nash CL Jr,Nussbaum E,Brower EM

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND:Approximately 750,000 children in the United States with special health care needs will transition from pediatric to adult care annually. Fewer than half receive adequate transition care. METHODS:We had conversations with key informants representing clinicians who provide transition care, pediatric and adul...

journal_title：Pediatrics

authors： Davis AM,Brown RF,Taylor JL,Epstein RA,McPheeters ML

更新日期：2014-11-01 00:00:00

abstract：:The proper ethical conduct of studies to evaluate drugs in children is of paramount importance to all those involved in these types of studies. This report is an updated revision to the previously published guidelines from the American Academy of Pediatrics in 1995. Since the previous publication, there have been grea...

journal_title：Pediatrics

authors： Shaddy RE,Denne SC,Committee on Drugs and Committee on Pediatric Research.

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Treatment of otitis media is the most frequent reason for administering antibiotics to children in the United States. However, only limited data are available on medical effectiveness of antibiotic prescribing patterns for otitis media and their associated expenditures or the factors that influence antibioti...

journal_title：Pediatrics

authors： Berman S,Byrns PJ,Bondy J,Smith PJ,Lezotte D

更新日期：1997-10-01 00:00:00

abstract：:Increased hair loss a few months after delivering an infant is a common postpartum condition known as telogen effluvium. A much less common condition involving young infants is the hair-thread tourniquet syndrome, or toe tourniquet syndrome, which involves hair or thread becoming so tightly wrapped around an appendage...

journal_title：Pediatrics

authors： Strahlman RS

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:In past decades, numerous population- and hospital-based studies have revealed a relationship between migraine or headache and psychopathology in children. OBJECTIVE:To describe and assess all clinical studies on the prevalence and manifestations of psychological functioning and psychiatric comorbidity in c...

journal_title：Pediatrics

authors： Bruijn J,Locher H,Passchier J,Dijkstra N,Arts WF

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the relationship among the size of the lateral ventricles, head-circumference measure, and brain volumes. In addition, the association between ventricular dilatation and various brain lesions was defined. PATIENTS AND METHODS:A total of 257 preterm very low birth weight (...

journal_title：Pediatrics

authors： Maunu J,Parkkola R,Rikalainen H,Lehtonen L,Haataja L,Lapinleimu H,PIPARI Group.

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:The goal of this study was to develop an algorithm based on International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM), codes for classifying children with chronic disease (CD) according to level of medical complexity and to assess the algorithm's sensitivity and specificity. ...

journal_title：Pediatrics

authors： Simon TD,Cawthon ML,Stanford S,Popalisky J,Lyons D,Woodcox P,Hood M,Chen AY,Mangione-Smith R,Center of Excellence on Quality of Care Measures for Children with Complex Needs (COE4CCN) Medical Complexity Working Group.

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Childhood sleep-disordered breathing has an adverse impact on cognitive development, behavior, quality of life, and use of health care resources. Early viral infections and other immune-mediated responses may contribute to development of the chronic inflammation of the upper airway and hypertrophic upper airw...

journal_title：Pediatrics

authors： Montgomery-Downs HE,Crabtree VM,Sans Capdevila O,Gozal D

更新日期：2007-11-01 00:00:00

abstract：:Acute acetaminophen intoxication was studied in the dog to characterize pathogenesis and in the mouse as a model for antidotal research. In the dog, overt toxicity was manifested principally by cyanosis, facial and paw edema, gastrointestinal disturbance, and coma. Typical laboratory findings were methemoglobinemia, h...

journal_title：Pediatrics

authors： Piperno E,Mosher AH,Berssenbruegge DA,Winkler JD,Smith RB

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There is a common belief that children are not getting enough sleep and that children's total sleep time has been declining. Over the century, many authors have proposed sleep recommendations. The aim of this study was to describe historical trends in recommended and actual sleep durations for ...

journal_title：Pediatrics

authors： Matricciani LA,Olds TS,Blunden S,Rigney G,Williams MT

更新日期：2012-03-01 00:00:00

abstract：:Pediatricians in the Washington, DC, metropolitan area were surveyed to assess their readiness to deal with life-threatening emergencies in their offices. Information about emergency equipment, prearranged emergency plans, advanced life support training, and emergency medical services assistance was elicited. Recommen...

journal_title：Pediatrics

authors： Altieri M,Bellet J,Scott H

更新日期：1990-05-01 00:00:00

abstract：:Data on research participants and populations frequently include race, ethnicity, and gender as categorical variables, with the assumption that these variables exert their effects through innate or genetically determined biologic mechanisms. There is a growing body of research that suggests, however, that these variab...

journal_title：Pediatrics

authors：

更新日期：2000-06-01 00:00:00

abstract：:Postnatal ductal closure is stimulated by rising oxygen tension and withdrawal of vasodilatory mediators (prostaglandins, nitric oxide, adenosine) and by vasoconstrictors (endothelin-1, catecholamines, contractile prostanoids), ion channels, calcium flux, platelets, morphologic maturity, and a favorable genetic predis...

journal_title：Pediatrics

authors： Hamrick SEG,Sallmon H,Rose AT,Porras D,Shelton EL,Reese J,Hansmann G

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:To compare the diagnostic performance of the Centers for Disease Control and Prevention (CDC) and FITNESSGRAM (FGram) BMI standards for quantifying metabolic risk in youth. METHODS:Adolescents in the NHANES (n = 3385) were measured for anthropometric variables and metabolic risk factors. BMI percentiles wer...

journal_title：Pediatrics

authors： Laurson KR,Welk GJ,Eisenmann JC

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Approximately 1 in 5 child passenger deaths in the United States involves an alcohol-impaired driver, most commonly the child's own driver. The objective of this study was to document recent trends and state-specific rates of these deaths. METHODS:A descriptive analysis of 2001-2010 Fatality A...

journal_title：Pediatrics

authors： Quinlan K,Shults RA,Rudd RA

更新日期：2014-06-01 00:00:00