Abstract:
:Australia's National Immunisation Program (NIP) provides free influenza vaccination for children at high risk of severe influenza; a pilot-funded programme for vaccine in all children aged 6 months to <5 years in one of eight states, has seen poor vaccine impact, related to recent vaccine safety concerns. This retrospective review examined influenza hospitalizations in children aged <16 years from three seasons (2011-2013) at two paediatric hospitals on opposite sides of the country. Comparisons of this cohort were made with state-based data on influenza-coded hospitalizations and national immunization register data on population-level immunization coverage. Of 740 hospitalizations, the majority were aged <5 years (476/740, 64%), and a substantial proportion (57%) involved healthy children, not currently funded for influenza vaccine. Intensive care unit admission occurred in 8·5%, and 1·5% of all children developed encephalitis. Use of antiviral therapy was uncommon (20·5%) and decreasing. Of those hospitalized, only 5·0% of at-risk children, who are currently eligible for free vaccine, and 0·7% of healthy children were vaccinated prior to hospitalization. This was consistent with low population-wide estimates of influenza vaccine uptake. It highlights the need to examine alternative strategies, such as universally funded paediatric influenza vaccination, to address disease burden in Australian children.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Li-Kim-Moy J,Yin JK,Blyth CC,Kesson A,Booy R,Cheng AC,Macartney Kdoi
10.1017/S0950268816003381subject
Has Abstractpub_date
2017-05-01 00:00:00pages
1451-1460issue
7eissn
0950-2688issn
1469-4409pii
S0950268816003381journal_volume
145pub_type
杂志文章abstract::Recent epidemiological data suggest a link between the consumption of bovine offal products and Shiga toxin-producing Escherichia coli (STEC) infection in Japan. This study thus examined the prevalence of STEC in various types of these foods. PCR screened 229 bovine offal products for the presence of Shiga toxin (stx)...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268811001105
更新日期:2012-04-01 00:00:00
abstract::This study investigated whether exposure to inactivated rabbit haemorrhagic disease virus (RHDV) can produce an antigenic response in rabbits and protect them from a subsequent challenge with virulent virus. The aim was to determine if the spreading of baits containing RHDV, which is a common management practice in Ne...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268805003754
更新日期:2005-08-01 00:00:00
abstract::Two epidemics of acute, watery diarrhoea in villages in North Arcot district, India, were investigated. The attack rates were 10.03 and 15.53 per 100 population, the median duration was 5 days and enteric pathogens were present in 56.8% and 60.3% of specimens from the two villages, but no predominant pathogen was iden...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268801005799
更新日期:2001-08-01 00:00:00
abstract::Although social networks are known to play an important role in drug-using behaviours associated with hepatitis C virus (HCV) infection, literature on social networks and HCV is inconsistent. This exploratory study examined HCV RNA distribution within a social network of anti-HCV-positive non-medical prescription opio...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268812000696
更新日期:2013-02-01 00:00:00
abstract::SUMMARYA prospective cohort study with a 1-year telephone follow-up was performed to estimate the incidence of surgical-site infections (SSIs) in hip and knee prostheses. Twenty-five public hospitals equipped with orthopaedic units in two Italian regions were involved. An 8-month surveillance period was set to obtain ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268810001627
更新日期:2011-05-01 00:00:00
abstract::In March 1997, an outbreak of Vero cytotoxin-producing Escherichia coli O157 (VTEC) infection occurred amongst holidaymakers returning from Fuerteventura, Canary Islands. For the investigation, a confirmed case was an individual staying in Fuerteventura during March 1997, with either E. coli O157 VTEC isolated in stoo...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268899002940
更新日期:1999-10-01 00:00:00
abstract::An epidemiological model was developed for rabies, linking the risk of disease in a secondary species (cats) to the temporal dynamics of disease in a wildlife reservoir (raccoons). Data were obtained from cats, raccoons, and skunks tested for rabies in the northeastern United States during 1992-2000. An epizootic algo...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268804002067
更新日期:2004-06-01 00:00:00
abstract::This analysis assessed the utility of the limiting antigen avidity assay (LAg). Samples of people who inject drugs (PWID) in Greece with documented duration of HIV-1 infection were tested by LAg. A LAg-normalized optical density (ODn) ⩽1·5 corresponds to a recency window period of 130 days. The proportion true recent ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268816002417
更新日期:2017-01-01 00:00:00
abstract::The aim of this study was to estimate the prevalence of hepatitis B exposure in the population of the Republic of Ireland, by measuring the prevalence of hepatitis B anti-core antibody in oral fluid collected by postal survey. A random multi-stage stratified sample of Irish households was obtained, using the Irish ele...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s095026880000491x
更新日期:2000-12-01 00:00:00
abstract::Pre-existing health conditions may exacerbate the severity of coronavirus disease 2019 (COVID-19). We aimed to estimate the case-fatality rate (CFR) and rate ratios (RR) for patients with hypertension (HBP) and diabetes mellitus (DM) in the New York state. We obtained the age-specific number of COVID-19 confirmed case...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268821000066
更新日期:2021-01-08 00:00:00
abstract::After a Christmas party in a restaurant, 48 (68%) of the 82 guests contracted calicivirus gastroenteritis. The epidemiological investigation showed that salad was strongly associated with the disease episode (RR = 2.43, P = 0.0005). Similar symptoms occurred among other customers who had had a meal at the same restaur...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s095026889900299x
更新日期:1999-12-01 00:00:00
abstract::Laboratory-based surveillance of invasive pneumococcal infections in adults in Finland from 1983 to 1992 identified 862 episodes of pneumococcal bacteraemia and 97 episodes of meningitis. The overall incidence of invasive pneumococcal infections was 9.1 per 100,000 for all adults per year, but 27.1, 35.8, and 44.5 per...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268896007169
更新日期:1997-02-01 00:00:00
abstract::Phylogenetic analyses of bartonella have suggested divergence between bartonellae that infect mammals native to the Old and New Worlds. We characterized bartonella isolated from Eastern grey squirrels (Sciurius carolinensis) in the United States and from grey and red squirrels (Sciurus vulgaris) in the United Kingdom ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268802007768
更新日期:2002-12-01 00:00:00
abstract::We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruse...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268818002017
更新日期:2018-10-01 00:00:00
abstract::Réunion Island (Indian Ocean) has been suffering from its first known Chikungunya virus (CHIKV) epidemic since February 2005. To achieve a better understanding of the disease, a questionnaire was drawn up for hospital staff members and their household. CHIKV infected about one-third of the studied population, the prop...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268807008424
更新日期:2008-02-01 00:00:00
abstract::British cattle were infected with the South African (Neethling) strain of lumpy skin disease virus (LSDV) and their clinical signs monitored over a 3-week period. Different routes of infection were assessed for effect on the clinical characteristics of the disease by using a clinical scoring system. Neither of 2 anima...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800052067
更新日期:1995-02-01 00:00:00
abstract::A large-scale measles outbreak (11 495 reported cases, 60% aged ≥15 years) occurred in Georgia during 2013-2015. A nationwide, multistage, stratified cluster serosurvey for hepatitis B and C among persons aged ≥18 years conducted in Georgia in late 2015 provided an opportunity to assess measles and rubella (MR) suscep...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268819002048
更新日期:2019-12-11 00:00:00
abstract::We compared gastroenteritis cases that consulted a general practitioner (GP) with those who did not in a community-based study and also with those in a GP-based study. We aimed to identify factors associated with consultation, and with inclusion of cases by GPs, and secondly to study the effects on the frequency of de...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268801006082
更新日期:2001-12-01 00:00:00
abstract::Strains of Candida albicans can be differentiated by the morphological features of streak colonies developed on malt agar. A morphotyping system is proposed, where numerical codes are assigned primarily on the basis of the nature and extent of marginal fringing and the surface topography of the streak colony. The syst...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800067911
更新日期:1987-10-01 00:00:00
abstract::Chronic hepatitis C virus (HCV) infection is the most common blood-borne infection in the USA. Estimating prevalence is critical for monitoring diagnosis, treatment, and cure and for allocating resources. Surveillance data reported to the New York City (NYC) Health Department, 2000-2015, were used to estimate HCV prev...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881800170X
更新日期:2018-09-01 00:00:00
abstract::The distribution of the meningococcal insertion sequence IS1301 was analysed in 496 strains of different serogroups and clonal lineages of Neisseria meningitidis, and in 64 neisserial strains other than N. meningitidis. IS1301 was found in meningococci, but not in apathogenic Neisseria sp. and Neisseria gonorrhoeae. T...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268899003647
更新日期:2000-04-01 00:00:00
abstract::The efficacy of interferon A (rIFN-alpha 2A), an Escherichia coli-derived interferon, in the prophylaxis of acute upper respiratory tract infection, was evaluated in a community-based double-blind placebo-controlled study in the Australian winter of 1985. The trial population of 412 healthy volunteers (190 males and 2...
journal_title:Epidemiology and infection
pub_type: 临床试验,杂志文章
doi:10.1017/s0950268800029484
更新日期:1988-12-01 00:00:00
abstract::In this study we collected and analysed data of the severe burn patients at our institution over an 11-year period in order to shed light on the controversial role of bloodstream infection (BSI) as a predictive factor for mortality in this burn population. The factors examined were age, total body surface area, smoke ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268813002501
更新日期:2014-10-01 00:00:00
abstract::This nested case-control study investigated the risk factors for gastroenteritis in a cohort using rainwater as their primary domestic water source. Consumption of beef [odds ratio (OR) 2·74, 95% confidence interval (CI) 1·56-4·80], handling of raw fresh chicken in the household (OR 1·52, 95% CI 1·02-2·29) and animal ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268810001159
更新日期:2011-04-01 00:00:00
abstract::From 1985 to 1988, a total of 2496 swine sera from 60 farms in the Tohoku District of the Honshu Island of Japan were examined for antibodies to swine haemagglutinating encephalomyelitis virus (HEV), human coronavirus (HCV) and bovine coronavirus (BCV) by haemagglutination-inhibition (HI) test. Antibodies to HEV 67N s...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268899002332
更新日期:1999-06-01 00:00:00
abstract::Neisseria cuniculi was isolated, between March 1987 and March 1989, from 38 cases of respiratory disease in small and large ruminants. In all but five cases N. cuniculi was cultured together with other potential respiratory pathogens. A survey was conducted to assess the prevalence of N. cuniculi in the pharyngeal reg...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800048184
更新日期:1990-12-01 00:00:00
abstract::During a 3-year period Branhamella catarrhalis was isolated in significant numbers from 239 (1.3%) of 19,488 specimens of sputum sent for routine microbiological examination at a 700-bed general hospital. The majority of patients (83%) were over 60 years of age and 65% were male. There was a distinct seasonal variatio...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800067947
更新日期:1987-10-01 00:00:00
abstract::A total of 3522 samples of serum, collected anonymously from women attending an antenatal clinic, was tested for hepatitis B surface antigen and antibody to hepatitis C. The prevalence of anti-HCV was low; only five confirmed positives were found (0.14%). The prevalence of hepatitis B overall was 0.56%, but was 1.04% ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800068539
更新日期:1994-12-01 00:00:00
abstract::Large outbreaks of Q fever in The Netherlands have provided a unique opportunity for studying longitudinal serum antibody responses in patients. Results are presented of a cohort of 344 patients with acute symptoms of Q fever with three or more serum samples per patient. In all these serum samples IgM and IgG against ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268812000404
更新日期:2013-01-01 00:00:00
abstract::Two enterotoxins, shigella enterotoxin 1 (SHET1) and shigella enterotoxin 2 (SHET2) have been recently characterized and are believed to play a role in the clinical manifestation of shigellosis. One hundred and twenty-one isolates of Shigella spp. of 13 different serotypes and variants and 10 isolates of enteroinvasiv...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268802006866
更新日期:2002-06-01 00:00:00