Abstract:
BACKGROUND:Insulin resistance has been associated with cytokines, including interleukin-6 and tumor necrosis factor alpha soluble receptor, both of which are elevated in chronic obstructive pulmonary disease (COPD). Few studies have investigated the relationship between pulmonary function tests using spirometry (PFT) and fasting plasma glucose (FPG) or glycated hemoglobin (HbA1c) levels in Japanese participants. The purpose of this study was to clarify the relationship between PFT in Japanese people who had health checkups and their FPG or HbA1c levels. In the context of preventative medicine, we intend to connect early detection of COPD to an index of blood sugar. METHODS:From August 2013 through March 2014, 1019 participants underwent health checkups. PFT, FPG, and HbA1c measurements were conducted. HbA1c levels were measured according to National Glycohemoglobin Standardization Program guidelines. RESULTS:Participants with FPG ≥100 mg/dL and HbA1c ≥5.6% showed a significantly lower forced expiratory volume in 1 s:forced vital capacity ratio (FEV1/FVC) compared to participants with lower FPG and Hb1Ac levels. Prevalence of FEV1/FVC values <70% in PFT differed significantly depending on sex, age, body mass index, FPG, HbA1c, and smoking habits. Age (≥60 years), HbA1c (≥5.6%), and current or former smoking were associated with FEV1/FVC values <70%. CONCLUSION:In Japan, HbA1c levels were higher in participants with FEV1/FVC values <70% in PFT than in those with FEV1/FVC ≥70%. In preventive medicine, PFT by spirometry should be performed in elderly participants with elevated HbA1c levels who are current or former smokers.
journal_name
J Epidemioljournal_title
Journal of epidemiologyauthors
Baba S,Takashima T,Hirota M,Kawashima M,Horikawa Edoi
10.1016/j.je.2016.10.008subject
Has Abstractpub_date
2017-11-01 00:00:00pages
511-515issue
11eissn
0917-5040issn
1349-9092pii
S0917-5040(17)30002-3journal_volume
27pub_type
杂志文章abstract:BACKGROUND:We reutilized the existing Three-Prefecture Cohort to evaluate the relationship between lifestyle factors and the incidence or mortality from non-communicable diseases. METHODS:This study was a prospective population-based observation conducted from the 1980s to 2000 in three prefectures (Miyagi, Aichi, and...
journal_title:Journal of epidemiology
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更新日期:2017-04-01 00:00:00
abstract:INTRODUCTION:To clarify the incidences of metabolic syndrome (MS) and risks in young Japanese adults by gender. METHODS:A total of 58,901 adults who had undergone annual health check-ups in 2010 without a diagnosis of MS or missing data were divided into three age groups (20s through 40s) by gender. Participants were ...
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更新日期:2020-05-05 00:00:00
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更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:The effect of the interaction between long-term mental stress and eating habits on weight gain has not been confirmed in humans. METHODS:A population of 1080 healthy Japanese male local government employees without lifestyle-related diseases at baseline were studied [corrected]. Height and weight were measu...
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abstract::On the basis of 351 one-day weighed diet records, we selected foods/recipes contributing to nutrients of interest for a data-based food frequency questionnaire by contribution analysis and multiple regression analysis. Total fat was largely of animal and vegetable origin, irrespective of analytic methods. Saturated fa...
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更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:Previous Japanese studies have led to the erroneous conclusion of antioxidant capacity (AOC) intakes of the overall Japanese diet due to limitations in the number and types of food measured, especially in rice and seafood intake. The aims of the study were to construct an AOC database of foods representative...
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更新日期:2020-09-19 00:00:00
abstract::The Atomic Bomb Casualty Commission (ABCC), the predecessor of the Radiation Effects Research Foundation (RERF), was established in 1947 to conduct long-term, comprehensive epidemiological and genetic studies of the atomic-bomb (A-bomb) survivors. Today this study still depends upon the voluntary cooperation of severa...
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更新日期:1996-08-01 00:00:00
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更新日期:2005-06-01 00:00:00
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doi:10.2188/jea.JE20120033
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pub_type: 杂志文章,评审
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更新日期:2017-03-01 00:00:00
abstract::There are suggestions that women have higher relative risks of lung cancer than men given similar levels of tobacco exposure, implying that sex-related hormones may influence lung cancer risk. We evaluated the association between lung cancer risk and menstrual and reproductive factors on a subset of self-responding fe...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.13.22
更新日期:2003-01-01 00:00:00
abstract::To evaluate the effects of passive smoking identified by urine cotinine on serum carotenoids and alpha-tocopherol, we categorized 124 residents in a rural city of Japan into 4 groups by their urine cotinine/creatinine (Cot/Cr) ratio (u.d. (undetectable); low (0-50 ng/mg); moderate (50-120 ng/mg); high (> 120 ng/mg)) a...
journal_title:Journal of epidemiology
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更新日期:1998-08-01 00:00:00
abstract:BACKGROUND:Cigarette smoking and oral contraceptive (OC) use have been associated with cervical neoplasia, and the combination of smoking and OC use could influence cervical carcinogenesis. We aimed to assess the joint effect of smoking and OC use on the risk of cervical intraepithelial neoplasia (CIN). METHODS:From a...
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abstract:BACKGROUND:The adverse effects of maternal smoking on the health of pregnant women have been examined mostly on a disease-by-disease basis. The aims of this study were to evaluate simultaneously the effects of smoking during pregnancy on various obstetric complications, using data from a large medical database, and to ...
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更新日期:2011-01-01 00:00:00
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journal_title:Journal of epidemiology
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更新日期:2018-02-05 00:00:00
abstract:BACKGROUND:Many studies have reported an association between physical activity and cardiovascular disease (CVD); however, the effect of physical activity remains controversial. Few such studies have been conducted in Japan. Therefore, we examined the relationship between physical activity and death from CVD using prosp...
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更新日期:2010-01-01 00:00:00
abstract::We conducted self-administered questionnaire surveys of school children living in the vicinity of Mt. Sakurajima using ATS-DLD questionnaire. In this paper, we report the results of analysis comparing the proportion of children with asthma-like disease in the area exposed to the volcanic ash and gases released by Mt. ...
journal_title:Journal of epidemiology
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更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:Asian dust events are caused by dust storms that originate in the deserts of China and Mongolia and drift across East Asia. We hypothesized that the dust events would increase incidence of out-of-hospital cardiac arrests by triggering acute events or exacerbating chronic diseases. METHODS:We analyzed the Ut...
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更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Few studies have examined the association between seaweed intake and blood pressure in children. We conducted an intervention study to investigate whether seaweed intake affects blood pressure. METHODS:Subjects were children aged 4 to 5 years attending a preschool in Aichi Prefecture, Japan, in 2010. Among ...
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doi:10.2188/jea.JE20190176
更新日期:2021-01-05 00:00:00
abstract:BACKGROUND:The present study examined the prevalence of diabetes in Japan during the late 1990s and early 2000s using the Japan Public Health Center-based Prospective Diabetes cohort. We also investigated the distributions of HbA1c values in noncompliant diabetic participants in the cohort. METHODS:A total of 28 183 r...
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更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To determine whether or not the breast milk feeding has a role in the prevalence of atopic dermatitis among children. METHODS:The target population of the study was all children participating in health check-up program for 3-year-old children in 60 municipalities locating 10 selected prefectures during desig...
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更新日期:2000-03-01 00:00:00