Abstract:
BACKGROUND:The effects of body mass index (BMI) and reproductive factors may vary among breast cancer molecular subtypes, evidence of which is lacking in East Asia. METHODS:From 2002 to 2010, 1256 breast cancer patients and 1416 healthy women were recruited. Anthropometric and reproductive factors were collected from medical charts. Breast cancer subtype was defined by ER, PR, and HER2 status. Polytomous logistic regression was used to evaluate associations between risk factors and breast cancer subtypes, with subgroup analysis by menopausal status. A meta-analysis of relevant published studies in East Asia was also performed. RESULTS:In our case-control study, late menarche was negatively associated with luminal tumor risk (Ptrend = 0.03). Higher BMI was associated with risk of both luminal and triple-negative tumors (Ptrend<0.001). Late age at first live birth was associated with a 1.41- to 2.08-fold increased risk of all subtypes, while late menopause increased risk by 2.62-5.56 times. Heterogeneity of these associations was not detected for different menopausal statuses. The meta-analysis revealed a positive dose-response relationship between BMI and risk of both luminal and ER-PR- subtypes (Ptrend<0.05). Early menarche and nulliparity increased luminal tumor risk by 1.39 and 1.26 times, respectively. Non-breastfeeding also increased the risk of all subtypes. CONCLUSIONS:For East Asian women, overweight, late menopause, and lack of breastfeeding appear to increase risk of both luminal and ER-PR- tumors. Early menarche and nulliparity mainly impacted luminal tumor risk. These associations were not impacted by menopausal status.
journal_name
J Epidemioljournal_title
Journal of epidemiologyauthors
Li H,Sun X,Miller E,Wang Q,Tao P,Liu L,Zhao Y,Wang M,Qi Y,Li Jdoi
10.1016/j.je.2016.05.002subject
Has Abstractpub_date
2017-04-01 00:00:00pages
143-151issue
4eissn
0917-5040issn
1349-9092pii
S0917-5040(16)30154-Xjournal_volume
27pub_type
杂志文章,meta分析abstract:BACKGROUND:Previous Japanese studies have led to the erroneous conclusion of antioxidant capacity (AOC) intakes of the overall Japanese diet due to limitations in the number and types of food measured, especially in rice and seafood intake. The aims of the study were to construct an AOC database of foods representative...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.JE20190237
更新日期:2020-01-25 00:00:00
abstract:BACKGROUND:Strategies for preventing premature cardiovascular disease include measures to control its risk factors. To plan such activities, prevalence of these factors must be known. Data regarding risk factor prevalence is limited in Bangladesh and measurement of biochemical factors is not always feasible. The aim of...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.14.63
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:The incidence of idiopathic nephrotic syndrome (INS) varies among countries, with Asia reporting a higher incidence in comparison with Western countries. We investigated the epidemiologic features of INS and attempted to identify factors that predispose individuals to develop end-stage renal disease (ESRD). ...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.JE20120033
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Glucose intolerance in patients with amyotrophic lateral sclerosis (ALS) has been inconsistently reported. Evidence for the association of ALS and diabetes mellitus is limited. We aimed to assess the overall and age- and sex-specific risks of ALS among patients with diabetes in Taiwan. METHODS:The study coh...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.JE20140176
更新日期:2015-01-01 00:00:00
abstract::The effect of exposure to Japanese cedar pollen (JCP) in early life on subsequent sensitization to it was evaluated. Specific IgE antibody to JCP was examined in 440-504 school children in a rural town each year during 1995-98. The amount of dispersed pollen measured by a Durham sampler widely ranged from 165 to 5941 ...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.10.42
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The present study examined the prevalence of diabetes in Japan during the late 1990s and early 2000s using the Japan Public Health Center-based Prospective Diabetes cohort. We also investigated the distributions of HbA1c values in noncompliant diabetic participants in the cohort. METHODS:A total of 28 183 r...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.je20130196
更新日期:2014-01-01 00:00:00
abstract::The urban-rural difference in cardiovascular risk factors and stroke mortality throughout Japan was examined in a cohort by using hierarchical data structure. The subjects were 9,309 men and women aged > or = 30 years who were residents of 294 areas in 211 municipalities of Japan in 1980; they were followed up until 1...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.je2008034
更新日期:2008-01-01 00:00:00
abstract::Kawasaki disease in China was described for the first time in 1976 in Taiwan, and in 1978 in mainland, respectively. Questionnaire surveys had been conducted in both of the area of China and showed that the Kawasaki disease patients increased year by year. No data on incidence rates were available for these surveys be...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.11.103
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Asian dust events are caused by dust storms that originate in the deserts of China and Mongolia and drift across East Asia. We hypothesized that the dust events would increase incidence of out-of-hospital cardiac arrests by triggering acute events or exacerbating chronic diseases. METHODS:We analyzed the Ut...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.JE20140179
更新日期:2015-01-01 00:00:00
abstract::The human population is exposed to both the ultraviolet A (UVA) and B (UVB) regions of the solar spectrum. UVB induces mainly dipyrimidine photoproducts in DNA by a direct photochemical mechanism, whereas UVA is absorbed by other cellular constituents and induces mainly oxidative damage indirectly. The proportions of ...
journal_title:Journal of epidemiology
pub_type: 杂志文章,评审
doi:10.2188/jea.9.6sup_48
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:Many studies have suggested that the daily emotional interactions between a child and his/her caregiver play a significant role in his/her development. The purpose of this study was to determine whether the trajectory patterns of parenting patterns of caregivers raising toddlers affect the social competence ...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.je20090172
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:The estimation of incidence rates of infectious diseases based on the sentinel surveillance data is rather rare. We attempted to estimate these in 2000 in Japan by the surveillance data, and to evaluate their biases. METHODS:We used the incidences of influenza-like illness and 12 pediatric diseases in each ...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.13.136
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:Previous studies suggest that neighborhood social capital is associated with children's mental health. The purpose of this study was to examine the association between neighborhood collective efficacy and children's psychosocial development. METHODS:We used data on children and their parents (n = 918) who w...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.1016/j.je.2016.08.018
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:We attempted to apply the model of effort-reward imbalance (ERI) to school settings in order to measure students' psychosocial stress and analyze its association with self-rated health in adolescents. METHODS:A cross-sectional survey was conducted in Kunming, China among 1004 Chinese students (468 boys and ...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.je20090057
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Prolonged periods of sitting time can be adversely associated with older adults' well-being and functional capacities. Understanding patterns and contexts of sedentary behaviors (SB) can inform approaches to prevention. This study examined Japanese older adults' objectively-assessed patterns and reported dom...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.JE20180041
更新日期:2019-09-05 00:00:00
abstract:INTRODUCTION:To clarify the incidences of metabolic syndrome (MS) and risks in young Japanese adults by gender. METHODS:A total of 58,901 adults who had undergone annual health check-ups in 2010 without a diagnosis of MS or missing data were divided into three age groups (20s through 40s) by gender. Participants were ...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.JE20180246
更新日期:2020-05-05 00:00:00
abstract:BACKGROUND:The longevity of Japanese is thought to be associated with psychosocial factors such as sense of coherence, social support, and social capital. However, the actual factors responsible and the extent of their contribution to individual health status are not known. METHODS:The Aichi Gerontological Evaluation ...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.je20100135
更新日期:2011-01-01 00:00:00
abstract::A positive association between hyperuricemia and cardiovascular disease has been reported, but no study has evidenced yet the precise role of serum uric acid in the development of cardiovascular disease. In addition, no epidemiological studies have so far documented a decreased risk of cancer among people with hyperur...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.10.403
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:It has been reported that fruit intake protects against cardiovascular disease (CVD). However, most of the relevant studies were conducted in Western countries, and only a few investigated Japanese populations. The present cohort study assessed the effect of citrus fruit intake on the incidence of CVD and it...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.je20100084
更新日期:2011-01-01 00:00:00
abstract::We examined apolipoprotein E (Apo E) polymorphism and methylenetetrahydrofolate reductase (MTHFR) 677 C to T mutation by using the polymerase chain reaction (PCR) method in 100 elderly Japanese aged 60 or more, and assessed whether these genetic factors are associated with an increased risk for the clinical phenotypes...
journal_title:Journal of epidemiology
pub_type: 临床试验,杂志文章
doi:10.2188/jea.10.163
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:The method for estimating incidence of infectious diseases from sentinel surveillance data has been proposed. In Japan, although the annual incidence rates of influenza and pediatric diseases estimated using the method were reported, their weekly incidence rates have not. METHODS:The weekly sex- and age-spe...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.17.s32
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Evidence for an association between vitamin D status and breast cancer is now more convincing, but is uncertain in subtropical areas like Taiwan. This hospital-based case-control study examined the relationship of breast cancer with vitamin D intake and sunlight exposure. METHODS:A total of 200 incident bre...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.je20100088
更新日期:2011-01-01 00:00:00
abstract::On the basis of 351 one-day weighed diet records, we selected foods/recipes contributing to nutrients of interest for a data-based food frequency questionnaire by contribution analysis and multiple regression analysis. Total fat was largely of animal and vegetable origin, irrespective of analytic methods. Saturated fa...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.9.78
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:Several investigations have adopted self-reported intake frequency of fish as a surrogate for intake of long-chain n-3 fatty acids, for which protective effects against cancer have been suggested. Whether reported fish consumption reflects the fatty acid intake, however, has to be elucidated. METHODS:We exa...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.15.211
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:While the immunogenicity and effectiveness of seasonal influenza vaccines among subjects with severe motor and intellectual disability (SMID) are known to be diminished, the efficacy of the A/H1N1pdm vaccine has not been evaluated. METHODS:We prospectively evaluated 103 subjects with SMID (mean age, 41.7 ye...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.JE20150036
更新日期:2016-06-05 00:00:00
abstract:BACKGROUND:Inflammatory gene polymorphisms are potentially associated with atherosclerosis risk, but their age-related effects are unclear. To investigate the age-related effects of inflammatory gene polymorphisms on arterial stiffness, we conducted cross-sectional and 5-year follow-up studies using the cardio-ankle va...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.je20130054
更新日期:2013-01-01 00:00:00
abstract::Most ecological studies investigating the relationship between incidence and/or mortality of skin cancer and surrogate measures of ultraviolet radiation B (UVB) have been conducted among the Caucasian population. The objective of the present study was therefore to assess the geographical correlation between ambient UV...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.9.6sup_123
更新日期:1999-12-01 00:00:00
abstract::We hypothesized that validity of semiquantitative food frequency questionnaire would be affected by food diversity (variety of foods consumed), because greater food diversity may be related to greater within-individual variation of nutrient intake, which can attenuate the correlation coefficient measuring validity of ...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.8.297
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:Japan's historically low immigration rate and monolingual culture makes it a particularly interesting setting for clarifying non-national medical care. Our study objective was to examine disease patterns and outcome differences between Japanese and non-Japanese patients in a rapidly globalizing nation. METH...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.JE20200211
更新日期:2020-12-05 00:00:00
abstract:BACKGROUND:The association of proteinuria and reduced estimated glomerular filtration rate (eGFR) with cognition needs more clarification. We cross-sectionally examined whether proteinuria and reduced eGFR, even in moderate stages, were independently associated with lower cognition in a community-based sample of elderl...
journal_title:Journal of epidemiology
pub_type: 杂志文章
doi:10.2188/jea.JE20180258
更新日期:2020-06-05 00:00:00