Abstract:
PURPOSE:Perianal fistulous disease is present in 10-15% of children with Crohn's disease (CD) and is frequently complex and refractory to treatment, with one-third of patients having recurrent lesions. We conducted a systematic review of the literature to examine the best surgical strategy or strategies for pediatric complex perianal fistulous disease (CPFD) in CD. METHODS:We searched CENTRAL, MEDLINE, EMBASE, and CINAHL for studies discussing at least one surgical strategy for the treatment of pediatric CPFD in CD. Reference lists of included studies were hand-searched. Two researchers screened all studies for inclusion, quality assessed each relevant study, and extracted data. RESULTS:One non-randomized prospective and two retrospective studies met our inclusion criteria. Combined use of setons and infliximab therapy shows promise as a first-line treatment. A specific form of fistulectomy, "cone-like resection," also shows promise when combined with biologics. Endoscopic ultrasound to guide medical and surgical management is feasible in the pediatric population, though it is unclear if it improves outcomes. CONCLUSION:There is a paucity of evidence regarding the treatment of CPFD in the pediatric population, and further research is required before recommendations can be made as to what, if any, surgical management is optimal.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Kantor N,Wayne C,Nasr Adoi
10.1007/s00383-017-4067-6subject
Has Abstractpub_date
2017-05-01 00:00:00pages
551-557issue
5eissn
0179-0358issn
1437-9813pii
10.1007/s00383-017-4067-6journal_volume
33pub_type
杂志文章,评审abstract:PURPOSE:Pancreatic neoplasms are uncommon in children. This study sought to analyze the clinical and pathological features of surgically resected pancreatic tumors in children and discuss management strategies. METHODS:We conducted a retrospective review of patients ≤21 years with pancreatic neoplasms who underwent su...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-3925-y
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:Laparoscopic-assisted anorectoplasty (LAARP) is a minimally invasive procedure in which the levator ani muscle is left to potentially improve postoperative fecal continence. This study aimed to retrospectively evaluate postoperative complications and long-term outcomes of fecal continence after LAARP and compar...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4323-4
更新日期:2018-10-01 00:00:00
abstract::The purpose of this study is to evaluate the efficacy of intraoperative radiation therapy (IORT) and the problem of securing the IORT field in advanced pediatric neuroblastoma. Between 1996 and 2005, 12 children received IORT for advanced pediatric neuroblastoma patients. Electron beam energies ranged from 10 to 12 Me...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2065-9
更新日期:2007-12-01 00:00:00
abstract::It is unknown whether noncomplicated acute appendicitis cause bacterial translocation. In this study, we aimed to test development of the bacterial translocation in the patients who were operated for acute appendicitis. In this prospective study, 10 control patients who underwent elective operations because of other r...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-1899-5
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:Tracheoesophageal fistula (TEF) is a bellwether for a country's ability to care for sick newborns. We aim to review the existing literature from low- and middle-income countries in regard to management of those newborns and the possible approaches to improve their outcomes. METHODS:A review of the existing Eng...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-020-04639-7
更新日期:2020-05-01 00:00:00
abstract::Bronchogenic cysts are congenital malformations of the tracheobronchial tree. We describe a 20-month-old male who presented with persistent non-bilious emesis; manometry and imaging were consistent with esophageal achalasia. During a planned laparoscopic Heller myotomy, an intramural bronchogenic cyst was discovered i...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-3994-y
更新日期:2017-01-01 00:00:00
abstract::Retrocaval ureter is a relatively rare anomaly that usually manifests in the third or fourth decades. Symptoms are due to ureteric obstruction, either extrinsic by the abnormal inferior vena cava (IVC), or intrinsic ureteric hypoplasia. Surgery is needed for symptomatic cases and involves transection and relocation of...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-1038-x
更新日期:2004-02-01 00:00:00
abstract::A modified technique of laparoscopic pyloromyotomy was used to treat infantile hypertrophic pyloric stenosis. Introducing a 5-mm periumbilical port for visualization, two stab wounds are made on either side laterally to directly insert 2.7-mm instruments for manipulation. From the left, the stomach is grasped - not th...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050307
更新日期:1998-04-01 00:00:00
abstract:PURPOSE:Primary spontaneous pneumothorax (PSP) is managed in accordance with the adult British Thoracic Society (BTS) guidelines due to lack of paediatric evidence and consensus. We aim to highlight the differences and provide a best practice surgical management strategy for PSP based on experience of two major paediat...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3787-8
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:The aim of this study was to determine if the placement of prophylactic drains influences the incidence of postoperative adverse events in neonates. METHODS:Neonatal patients undergoing laparotomy between April 2000 and December 2007 were prospectively assigned to aggressive peritoneal cavity lavage, without t...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-011-2905-5
更新日期:2011-09-01 00:00:00
abstract::Pseudoexstrophy is a rare variant of the exstrophy/epispadias complex, comprised of the musculoskeletal defects of classic exstrophy but with an intact bladder and urethra. We present a case of a neonate with left-sided gastroschisis and pseudoexstrophy, the first reported combination of these two anomalies. The anoma...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1217-4
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:Lgr5+ intestinal epithelial stem cells (ISCs) crucial for intestinal epithelial regeneration are impaired during necrotizing enterocolitis. This study aims to investigate the influence of different stressors on intestinal epithelial injury and regeneration in vitro. METHODS:Intestinal epithelial cells (IEC-18)...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-017-4183-3
更新日期:2018-02-01 00:00:00
abstract::Umbilical hernias occur frequently in children but complications are very rare and thus surgery is not routinely indicated. In this literature review, we report 19 cases of spontaneous evisceration of abdominal contents through umbilical hernias. Precipitating causes included umbilical ulceration or sepsis, crying, re...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-012-3076-8
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:Several procedures have been described for repair of distal hypospadias. However, these are not without any complications. Corpus spongiosum advancement is a new technique employed in our patients for distal hypospadias repair with excellent clinical outcome and no post-operative complications. PATIENTS AND ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-013-3292-x
更新日期:2013-06-01 00:00:00
abstract::Congenital obstructive uropathy is associated with significant morbidity and mortality in the human neonate. The pathophysiology of congenital obstructive uropathy is poorly understood. There are very few experimental models of prenatal obstruction of the urinary tract, except in the fetal lamb or inbred rats. Prenata...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1322-4
更新日期:2005-03-01 00:00:00
abstract:PURPOSE:Eosinophilic gastrointestinal disorders are rare in children and present with a broad spectrum of non-specific symptoms. To date, no guidelines for diagnosis, therapy and follow-up are validated. Aim of our study is to focus on eosinophilic colitis (EC), to determine a possible correlation between associated di...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-020-04832-8
更新日期:2021-01-07 00:00:00
abstract:BACKGROUND:Retinoids are essential for fetal and lung development. Beta-carotene(BC) is the main dietary retinoid source and beta-carotene-15,15'-oxygenase-1 and 2 (Bcmo1,2) is the primary enzyme generating retinoid from BC in adult mammalian tissues. Placenta has a major role in the retinol homeostasis in fetal life: ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3621-8
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To review the effectiveness of the longitudinal intestinal lengthening and tailoring (LILT) and serial transverse enteroplasty (STEP) operations in a cohort of patients with short bowel syndrome (SBS). METHODS:We conducted a retrospective analysis of children with SBS treated at our institution from 2004 until...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-019-04468-3
更新日期:2019-06-01 00:00:00
abstract::The Thomsen-Friedenreich cryptantigen (TCA) is located on the surface of all red cells, but is concealed by a layer of neuraminic acid. When bacteria that produce neuraminidase disrupt this coating, the TCA can be exposed and activated. If blood products containing antibody to the TCA are subsequently administered, ha...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050488
更新日期:1998-12-01 00:00:00
abstract::A testis is termed ectopic when it lies outside the normal line of descent. A case of testicular ectopia in which the testicle was located cranial and lateral to the internal ring dorsal to the external oblique muscle is reported in a 2-month-old boy. This highly aberrant ectopic testis was treated successfully by orc...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00178440
更新日期:1996-04-01 00:00:00
abstract::Modern plastic and reconstructive surgery continues to significantly improve the functional and aesthetic post-burn sequelae in children. It has become a major factor in restoring mobility, aesthetic appearance, self-esteem, and quality of life. The entire spectrum of plastic reconstructive procedures should be availa...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/BF01076930
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:Postoperative anxiety symptoms are distressing for both family and child. The aim of this study was to examine the prevalence of postoperative anxiety symptoms in children. METHODS:60 children aged 6-12 undergoing surgery were included in the study group. The study group was assessed three times in terms of ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4273-x
更新日期:2018-07-01 00:00:00
abstract::Inflammatory bowel disease (IBD) in children can cause significant impairment in linear growth, and delay in pubertal onset. The aim of this study was to assess the impact of surgery on linear growth in children with Crohn's disease (CD) who were resistant to medical therapy, and had documented evidence of growth impa...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1664-1
更新日期:2006-04-01 00:00:00
abstract::Pediatric germ cell tumors comprise 1-3% of all malignant pediatric tumors and are found in variable locations. We present the case of a term 3.7 kg neonate who was found to have a giant liver mass at birth, later determined to be an immature teratoma arising from the hepatoduodenal ligament. This case report and imag...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-017-4123-2
更新日期:2017-09-01 00:00:00
abstract::The aim of this study was to compare the safety and benefits of Soave's and Duhamel's pull-through procedures for the management of Hirschsprung's disease (HD). The patients consisted of 33 boys (85%) and six girls (15%), a ratio of 5.5:1. Their ages ranged from 1 day to 8 years. Rectal biopsy was performed to confirm...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1237-0
更新日期:2004-08-01 00:00:00
abstract::The factors that affect survival in patients with stage 4 neuroblastoma vary. Several prospective and retrospective studies have provided conflicting conclusions regarding the benefit of combining aggressive chemotherapy with complete surgical resection. We analyzed our experience to evaluate the effect of complete su...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1353-x
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:For a definitive diagnosis of congenital solitary kidney, renal scintigraphy is suggested as being the gold standard of ruling out ectopic functioning renal tissue, possibly missed by ultrasound. The aim of our study was to test ultrasonography precision in comparison with renal scintigraphy on a larger coho...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-019-04478-1
更新日期:2019-06-01 00:00:00
abstract::In severe vaginal malformations, when the distance between the upper vaginal pouch and perineum is too long (6 cm or more), reconstruction of the vagina can be performed by colonic interposition or by long cutaneous flaps obtained by the tissue expansion technique. Two female adolescents were treated using expanded la...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:
更新日期:1997-02-01 00:00:00
abstract::Postoperative abdominal evisceration may lead to high morbidity and mortality. The purpose of the present study was to determine possible risk factors, morbidity and mortality associated with abdominal evisceration in children. A total of 3,591 children underwent abdominal exploration in our clinic between 1983 and 20...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1722-8
更新日期:2006-08-01 00:00:00
abstract::Rhabdoid tumour of the kidney is not common. Presentation of such a lethal tumour along with blunt abdominal trauma is even rarer. We report such a case of Rhabdoid tumour of kidney which presented as renal trauma, and discuss the diagnostic difficulties and rapidly fatal outcome. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003839900290
更新日期:2000-01-01 00:00:00