Abstract:
:Forty patients with coronary artery disease and nonsustained ventricular tachycardia on ambulatory electrocardiographic monitoring underwent programmed electrical stimulation. In 22 patients, monomorphic ventricular tachycardia was induced at baseline drug-free electrophysiologic testing; 9 of these patients subsequently developed a clinical sustained ventricular tachyarrhythmia. In 18 patients, no tachycardia could be induced, and none of these 18 had subsequent tachycardia. In 25 of the 40 patients, arrhythmia management was guided by the results of electrophysiologic testing; this group included 11 patients who received antiarrhythmic therapy for induced ventricular tachycardia and 14 patients without inducible ventricular tachycardia who did not receive antiarrhythmic therapy. In the remaining 15 patients, arrhythmia management was not based on the results of electrophysiologic testing. Only two episodes of clinical sustained tachyarrhythmia occurred in the group receiving electrophysiologically guided therapy compared with seven episodes in the group treated without electrophysiologic guidance (p less than 0.01). Thus, in patients with coronary artery disease with nonsustained ventricular tachycardia on ambulatory electrocardiography, electrophysiologic testing can identify those at high and low risk for subsequent clinical tachycardia events. Furthermore, results of such testing can be used to optimize arrhythmia management in these patients.
journal_name
J Am Coll Cardioljournal_title
Journal of the American College of Cardiologyauthors
Klein RC,Machell Cdoi
10.1016/0735-1097(89)90066-1subject
Has Abstractpub_date
1989-07-01 00:00:00pages
155-61; discussion 162-3issue
1eissn
0735-1097issn
1558-3597pii
0735-1097(89)90066-1journal_volume
14pub_type
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更新日期:2004-03-03 00:00:00
abstract::Circulating biomarkers have become increasingly important in diagnosing and risk stratifying patients with heart failure (HF). While the natriuretic peptides have received much focus, there is increasing interest in the role of circulating cardiac troponin (cTn) in detecting myocardial injury (often subclinical) in th...
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更新日期:2010-09-28 00:00:00
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pub_type: 杂志文章,多中心研究
doi:10.1016/0735-1097(95)00124-i
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVES:The present retrospective analysis of data derived from a population-based study examined the relationship between intake of beta-receptor antagonists and plasma concentrations of the cardiac natriuretic peptides and their second messenger. BACKGROUND:Beta-receptor antagonists are widely used for treatment ...
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更新日期:2006-02-21 00:00:00
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更新日期:2011-02-15 00:00:00
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更新日期:1983-05-01 00:00:00
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更新日期:1997-06-01 00:00:00
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更新日期:2008-02-05 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1987-01-01 00:00:00
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更新日期:1997-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:1994-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-12-30 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2005-05-03 00:00:00
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更新日期:1993-08-01 00:00:00
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更新日期:2002-03-20 00:00:00
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更新日期:1985-03-01 00:00:00
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更新日期:2005-03-15 00:00:00
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更新日期:2008-03-18 00:00:00
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更新日期:2003-02-19 00:00:00
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更新日期:1997-01-01 00:00:00
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更新日期:2010-05-25 00:00:00
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更新日期:2005-08-02 00:00:00
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更新日期:1990-01-01 00:00:00