Abstract：
BACKGROUND:Smoking cessation may lead to depression in some smokers and result in increased risk of suicide. OBJECTIVE:To compare the risk of suicide attempts/behaviors associated with different smoking cessation medications among schizophrenic patients. METHODS:A retrospective cohort study was conducted using General Electric (GE) medical record database (1995-2011). The first day of being prescribed a smoking cessation medication defined as index date. Patients were followed up to one year from index date. Patients' suicide behaviors or attempts were identified through ICD-9 codes and E-codes. Cox proportional hazards model was applied to examine the association between smoking cessation medication and suicidal/self-injurious behaviors. RESULTS:Our cohort consisted of 3925 patients with diagnosis of schizophrenia or schizoaffective disorder who initiated cessation medication. Among them, 104 (2.65%) had suicide attempts or behavior within one-year follow up. However, statistically significant difference in the risk of suicide attempts/behaviors was not detected across cessation regimens in the Cox proportional hazard analysis. Only comorbidity index was found to be associated with suicide, which showed that higher Charlson comorbidity index was associated with higher risks of suicide behaviors within one year (HR=1.15, 95% CI=1.04-1.27). CONCLUSION:There were no significant differences in suicide attempts/behaviors with different cessation medications.
journal_name
Arch Psychiatr Nursjournal_title
Archives of psychiatric nursingauthors
Wu IH,Chen H,Bordnick P,Essien EJ,Johnson M,Peters RJ,Wang X,Abughosh SMdoi
10.1016/j.apnu.2016.08.001subject
Has Abstractpub_date
2017-02-01 00:00:00pages
62-67issue
1eissn
0883-9417issn
1532-8228pii
S0883-9417(16)30154-6journal_volume
31pub_type
杂志文章abstract：:Hospital discharge planning for clients with schizophrenia reduces client rehospitalization rates and improves their medication adherence. The effectiveness of caregiver participation in hospital discharge planning has seldom been explored. The purpose of this study was to examine the effectiveness of caregiver partic...
journal_title：Archives of psychiatric nursing
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journal_title：Archives of psychiatric nursing
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journal_title：Archives of psychiatric nursing
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journal_title：Archives of psychiatric nursing
pub_type： 杂志文章,meta分析
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journal_title：Archives of psychiatric nursing
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journal_title：Archives of psychiatric nursing
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journal_title：Archives of psychiatric nursing
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journal_title：Archives of psychiatric nursing
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journal_title：Archives of psychiatric nursing
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pub_type： 杂志文章,评审
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journal_title：Archives of psychiatric nursing
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journal_title：Archives of psychiatric nursing
pub_type： 杂志文章
doi：10.1016/0883-9417(92)90084-v
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journal_title：Archives of psychiatric nursing
pub_type： 杂志文章
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journal_title：Archives of psychiatric nursing
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journal_title：Archives of psychiatric nursing
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pub_type： 杂志文章
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journal_title：Archives of psychiatric nursing
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