Age affects sleep microstructure more than sleep macrostructure.

Abstract:

:It is well known that the quantity and quality of physiological sleep changes across age. However, so far the effect of age on sleep microstructure has been mostly addressed in small samples. The current study examines the effect of age on several measures of sleep macro- and microstructure in 211 women (22-71 years old) of the 'Sleep and Health in Women' study for whom ambulatory polysomnography was registered. Older age was associated with significantly lower fast spindle (effect size f2  = 0.32) and K-complex density (f2  = 0.19) during N2 sleep, as well as slow-wave activity (log) in N3 sleep (f2  = 0.21). Moreover, total sleep time (f2  = 0.10), N3 sleep (min) (f2  = 0.10), rapid eye movement sleep (min) (f2  = 0.11) and sigma (log) (f2  = 0.05) and slow-wave activity (log) during non-rapid eye movement sleep (f2  = 0.09) were reduced, and N1 sleep (f2  = 0.03) was increased in older age. No significant effects of age were observed on slow spindle density, rapid eye movement density and beta power (log) during non-rapid eye movement sleep. In conclusion, effect sizes indicate that traditional sleep stage scoring may underestimate age-related changes in sleep.

journal_name

J Sleep Res

authors

Schwarz JFA,Åkerstedt T,Lindberg E,Gruber G,Fischer H,Theorell-Haglöw J

doi

10.1111/jsr.12478

subject

Has Abstract

pub_date

2017-06-01 00:00:00

pages

277-287

issue

3

eissn

0962-1105

issn

1365-2869

journal_volume

26

pub_type

杂志文章
  • A quantitative analysis of the submentalis muscle electromyographic amplitude during rapid eye movement sleep across the lifespan.

    abstract::The current definition of rapid eye movement (REM) sleep without atonia has no quantitative character, and cut-off values above which the level of electromyographic tone can be considered to be 'excessive' are unclear. The aim of this study was to analyse the characteristics of chin electromyographic amplitude by mean...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2011.00958.x

    authors: Ferri R,Bruni O,Fulda S,Zucconi M,Plazzi G

    更新日期:2012-06-01 00:00:00

  • Sleep, age, and shiftwork experience.

    abstract::The effects of age and shiftwork experience (never, past, present) on sleep were studied in a sample of 3236 wage earners and retired workers by means of a questionnaire. The sample was composed of 32-, 42-, 52-, and 62-year-old subjects, and included both sexes and various occupational statuses. Age resulted in a con...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1046/j.1365-2869.1999.00170.x

    authors: Marquié JC,Foret J

    更新日期:1999-12-01 00:00:00

  • Low-grade albuminuria in children with obstructive sleep apnea.

    abstract::Small urinary protein loss (low-grade albuminuria or microalbuminuria) may reflect altered permeability of the glomerular filtration barrier. In the present study, it was hypothesized that children with obstructive sleep apnea have an increased risk of microalbuminuria compared with control subjects without sleep-diso...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12021

    authors: Varlami V,Malakasioti G,Alexopoulos EI,Theologi V,Theophanous E,Liakos N,Daskalopoulou E,Gourgoulianis K,Kaditis AG

    更新日期:2013-06-01 00:00:00

  • Multiple sleep latency test in narcolepsy type 1 and narcolepsy type 2: A 5-year follow-up study.

    abstract::Excessively sleepy teenagers and young adults without sleep-disordered breathing are diagnosed with either narcolepsy type 1 or narcolepsy type 2, or hypersomnia, based on the presence/absence of cataplexy and the results of a multiple sleep latency test. However, there is controversy surrounding this nomenclature. We...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12700

    authors: Huang YS,Guilleminault C,Lin CH,Chen CH,Chin WC,Chen TS

    更新日期:2018-10-01 00:00:00

  • P300 and sleep-related positive waveforms (P220, P450, and P900) have different determinants.

    abstract::Stimulus factors known to influence the amplitude of the well known endogenous event-related potential (ERP) component P300 were manipulated to determine whether they have the same, or a different, influence on the amplitude of positivities of the sleep ERPs identified as P220, P450, and P900. Behavioral responsivenes...

    journal_title:Journal of sleep research

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1365-2869.2001.00238.x

    authors: Hull J,Harsh J

    更新日期:2001-03-01 00:00:00

  • Copulatory activity increases slow-wave sleep in the male rat.

    abstract::It is believed that sexual activity increases the need to sleep in many species. However, the relationship between copulatory activity and sleep has been poorly studied. Several studies have observed variations in the sleep of female rats and women as a function of their reproductive state. These effects have been cor...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1046/j.1365-2869.2002.00304.x

    authors: Vazquez-Palacios G,Bonilla-Jaime H,Retana-Marquez S,Velazquez-Moctezuma J

    更新日期:2002-09-01 00:00:00

  • Social inequalities in sleep-disordered breathing: Evidence from the CoLaus|HypnoLaus study.

    abstract::Sleep-disordered breathing is a common condition, related to a higher cardiometabolic and neurocognitive risk. The main risk factors for sleep-disordered breathing include obesity, craniofacial characteristics, male sex and age. However, some studies have suggested that adverse socioeconomic circumstances and lifestyl...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12799

    authors: Petrovic D,Haba-Rubio J,Carmeli C,Vollenweider P,Heinzer R,Stringhini S

    更新日期:2019-10-01 00:00:00

  • Morningness-eveningness and daytime functioning in university students: the mediating role of sleep characteristics.

    abstract::The aim of this study was to explore the mediating role of sleep characteristics in the relationship between morningness-eveningness and three different aspects of daytime functioning: daytime sleepiness, depressive mood and substance use in university students. A multiple mediator model was proposed with sleep debt, ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12467

    authors: Bakotic M,Radosevic-Vidacek B,Koscec Bjelajac A

    更新日期:2017-04-01 00:00:00

  • Heart rate variability during sleep in children with partial epilepsy.

    abstract::Alterations in autonomic control of cardiac activity in epileptic patients have been reported by several studies in the past, and both ictal and interictal modifications of heart rate regulation have been described. Alterations of autonomic control of cardiac activity can play an important role in sudden unexplained d...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1046/j.1365-2869.2002.00283.x

    authors: Ferri R,Curzi-Dascalova L,Arzimanoglou A,Bourgeois M,Beaud C,Nunes ML,Elia M,Musumeci SA,Tripodi M

    更新日期:2002-06-01 00:00:00

  • Severe paediatric obesity and sleep: A mutual interactive relationship!

    abstract::Childhood severe obesity is a serious, urgent and complex global health problem with long-term co-morbidities. Obstructive sleep-disordered breathing is more common in obese children and adolescents. Increased body mass index is associated with an increase in apnea-hypopnea index. Obstructive sleep apnea leads to a de...

    journal_title:Journal of sleep research

    pub_type: 杂志文章,评审

    doi:10.1111/jsr.13162

    authors: Ischander MM,Lloyd RD Jr

    更新日期:2020-10-07 00:00:00

  • Sleep stabilizes visuomotor adaptation memory: a functional magnetic resonance imaging study.

    abstract::The beneficial effect of sleep on motor memory consolidation is well known for motor sequence memory, but remains unsettled for visuomotor adaptation in humans. The aim of this study was to characterize more clearly the influence of sleep on consolidation of visuomotor adaptation using a between-subjects functional ma...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2012.01059.x

    authors: Albouy G,Vandewalle G,Sterpenich V,Rauchs G,Desseilles M,Balteau E,Degueldre C,Phillips C,Luxen A,Maquet P

    更新日期:2013-04-01 00:00:00

  • Development of infant and toddler sleep patterns: real-world data from a mobile application.

    abstract::The aim of this study was to investigate the development of infant and toddler sleep patterns. Data were collected on 841 children (aged from birth to 36 months) via a free, publicly available, commercially sponsored iPhone app. Analyses were conducted on caregiver recordings of 156 989 sleep sessions across a 19-mont...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12414

    authors: Mindell JA,Leichman ES,Composto J,Lee C,Bhullar B,Walters RM

    更新日期:2016-10-01 00:00:00

  • The effect of complex cognitive training on subsequent night sleep.

    abstract::Using a nap design, we have recently shown that training at a complex cognitive task at bedtime improves objective sleep quality by reducing sleep fragmentation. In order to extend our findings to nighttime sleep, here we assess the impact of a multi-componential cognitive task at bedtime on the subsequent sleep episo...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12929

    authors: Cerasuolo M,Conte F,Cellini N,Fusco G,Giganti F,Malloggi S,Ficca G

    更新日期:2020-12-01 00:00:00

  • An experimental study of adolescent sleep restriction during a simulated school week: changes in phase, sleep staging, performance and sleepiness.

    abstract::This laboratory study investigated the impact of restricted sleep during a simulated school week on circadian phase, sleep stages and daytime functioning. Changes were examined across and within days and during a simulated weekend recovery. Participants were 12 healthy secondary school students (six male) aged 15-17 y...

    journal_title:Journal of sleep research

    pub_type: 临床试验,杂志文章

    doi:10.1111/jsr.12473

    authors: Agostini A,Carskadon MA,Dorrian J,Coussens S,Short MA

    更新日期:2017-04-01 00:00:00

  • Month of birth is not a risk factor for narcolepsy with cataplexy in the Netherlands.

    abstract::The month of birth has been proposed as a risk factor for narcolepsy, suggesting a harmful influence during early development. Several authors have described an excess of births in March in those developing narcolepsy later. Analysis methods in published studies varied, but no study corrected completely for possible c...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2011.00933.x

    authors: Donjacour CE,Fronczek R,LE Cessie S,Lammers GJ,VAN Dijk JG

    更新日期:2011-12-01 00:00:00

  • Sleep duration and mortality - Does weekend sleep matter?

    abstract::Previous studies have found a U-shaped relationship between mortality and (weekday) sleep duration. We here address the association of both weekday and weekend sleep duration with overall mortality. A cohort of 43,880 subjects was followed for 13 years through record-linkages. Cox proportional hazards regression model...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12712

    authors: Åkerstedt T,Ghilotti F,Grotta A,Zhao H,Adami HO,Trolle-Lagerros Y,Bellocco R

    更新日期:2019-02-01 00:00:00

  • Longitudinal sleep efficiency in the elderly and its association with health.

    abstract::The relationships between older age and sleep efficiency have traditionally been assessed using cross-sectional studies that ignore changes within individuals as they age. This research examines the determinants of sleep efficiency, the heterogeneity in an individual's sleep efficiency trajectory across a period of up...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12898

    authors: Didikoglu A,Maharani A,Tampubolon G,Canal MM,Payton A,Pendleton N

    更新日期:2020-06-01 00:00:00

  • Interleukin 6 as a marker of depression in women with sleep apnea.

    abstract::Depression is common in women with obstructive sleep apnea (OSA), but objective markers of depression have not yet been explored in such patients. We hypothesized that inflammation and antioxidant biomarkers may be associated with depression in a cohort of OSA women. We conducted a multicentre, cross-sectional study i...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.13035

    authors: Campos-Rodriguez F,Cordero-Guevara J,Asensio-Cruz MI,Sanchez-Armengol A,Sanchez-Lopez V,Arellano-Orden E,Gozal D,Martinez-Garcia MA

    更新日期:2021-02-01 00:00:00

  • Distinct features of fast oscillations in phasic and tonic rapid eye movement sleep.

    abstract::Spatiotemporal activity patterns of neurones are organized by different types of coherent network oscillations. Frequency content and cross-frequency coupling of cortical oscillations are strongly state-dependent, indicating that different patterns of wakefulness or sleep, respectively, support different cognitive or ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2012.01037.x

    authors: Brankačk J,Scheffzük C,Kukushka VI,Vyssotski AL,Tort AB,Draguhn A

    更新日期:2012-12-01 00:00:00

  • Associations between sleep duration and cognitive impairment in mild cognitive impairment.

    abstract::The prevalence of mild cognitive impairment (MCI) increases among elderly people and is associated with a high risk of dementia. Identifying factors that may contribute to the progress of MCI to dementia is critical. The objective of this study was to examine the association of objective sleep with cognitive performan...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12864

    authors: Basta M,Simos P,Vgontzas A,Koutentaki E,Tziraki S,Zaganas I,Panagiotakis S,Kapetanaki S,Fountoulakis N,Lionis C

    更新日期:2019-12-01 00:00:00

  • Effect of hypertension on upper airway function and sleep apnoea.

    abstract::Current evidence suggests that elevations in blood pressure during obstructive apnoeic episodes increase pharyngeal collapsibility and the severity of obstructive sleep apnoea. ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.1995.tb00193.x

    authors: Schwartz AR,Rowley JA,O'Donnell C,King ED,Mayor A,Smith PL

    更新日期:1995-06-01 00:00:00

  • Molecular approaches towards the isolation of sleep-related genes.

    abstract::Behavioural genetics is one of the most enticing fields in modern biology. Owing to straightforward and semiautomated techniques that can be used to measure locomotor activity, circadian rhythmicity is perhaps the best studied behaviour in animals. Thus, during the past decade, five essential circadian clock genes hav...

    journal_title:Journal of sleep research

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2869.1999.00001.x

    authors: Schibler U,Tafti M

    更新日期:1999-06-01 00:00:00

  • Lucid dreaming: an age-dependent brain dissociation.

    abstract::The current study focused on the distribution of lucid dreams in school children and young adults. The survey was conducted on a large sample of students aged 6-19 years. Questions distinguished between past and current experience with lucid dreams. Results suggest that lucid dreaming is quite pronounced in young chil...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2012.01022.x

    authors: Voss U,Frenzel C,Koppehele-Gossel J,Hobson A

    更新日期:2012-12-01 00:00:00

  • Stimulus-induced brain lactate: effects of aging and prolonged wakefulness.

    abstract::Both aging and sleep deprivation disturb the functions of the frontal lobes. Deficits in brain energy metabolism have been reported in these conditions. Neurons use not only glucose but also lactate as their energy substrate. The physiological response to elevated neuronal activity is a transient increase in lactate c...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2004.00401.x

    authors: Urrila AS,Hakkarainen A,Heikkinen S,Vuori K,Stenberg D,Häkkinen AM,Lundbom N,Porkka-Heiskanen T

    更新日期:2004-06-01 00:00:00

  • The duration of REM sleep epic, odes in normal sleep.

    abstract::The distributions of the durations of the first 3 REM sleep episodes have been analysed using a total of 134 overnight sleep recordings from 10 subjects. From investigation of the length of uninterrupted episodes of stage REM, it is shown that arousals to stage 0/1 could play an important part in the process of REM ex...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.1992.tb00025.x

    authors: Belyavin AJ

    更新日期:1992-06-01 00:00:00

  • Chronic partial sleep deprivation reduces brain sensitivity to glutamate N-methyl-D-aspartate receptor-mediated neurotoxicity.

    abstract::It has been hypothesized that insufficient sleep may compromise neuronal function and contribute to neurodegenerative processes. While sleep loss by itself may not lead to cell death directly, it may affect the sensitivity to a subsequent neurodegenerative insult. Here we examined the effects of chronic sleep restrict...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2011.00932.x

    authors: Novati A,Hulshof HJ,Granic I,Meerlo P

    更新日期:2012-02-01 00:00:00

  • Sleep duration and mortality: a systematic review and meta-analysis.

    abstract::Epidemiologic studies have shown that sleep duration is associated with overall mortality. We conducted a systematic review of the associations between sleep duration and all-cause and cause-specific mortality. PubMed was systematically searched up to January, 2008 to identify studies examining the association between...

    journal_title:Journal of sleep research

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1365-2869.2008.00732.x

    authors: Gallicchio L,Kalesan B

    更新日期:2009-06-01 00:00:00

  • Changes in dreaming induced by CPAP in severe obstructive sleep apnea syndrome patients.

    abstract::To study dream content in patients with severe obstructive sleep apnea syndrome (OSAS) and its modification with Continuous Positive Airway Pressure (CPAP) therapy. We assessed twenty consecutive patients with severe OSAS and 17 healthy controls. Polysomnograms were recorded at baseline in patients and controls and du...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2006.00553.x

    authors: Carrasco E,Santamaria J,Iranzo A,Pintor L,De Pablo J,Solanas A,Kumru H,Martínez-Rodríguez JE,Boget T

    更新日期:2006-12-01 00:00:00

  • Synchronized sleep duration is related to tonic vasoconstriction of thermoregulatory heat exchangers.

    abstract::The relationship between duration of the ultradian sleep cycle and intensity of tonic vasoconstrictor sympathetic outflow to thermoregulatory heat exchangers was studied in cats chronically implanted with EEG and EMG electrodes, and temperature transducers. Vasoconstrictor sympathetic outflow to heat exchangers was in...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.1995.tb00149.x

    authors: Azzaroni A,Parmeggiani PL

    更新日期:1995-03-01 00:00:00

  • Are serum ferritin and transferrin saturation risk markers for restless legs syndrome in young adults? Longitudinal and cross-sectional data from the Western Australian Pregnancy Cohort (Raine) Study.

    abstract::Restless legs syndrome has been associated with serum iron deficiency in clinical studies. However, studies investigating this relationship have had inconsistent results and there are no studies in young adults. Therefore, we investigated the relationship between serum measures of iron stores and restless legs syndrom...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12741

    authors: Lammers N,Curry-Hyde A,Smith AJ,Eastwood PR,Straker LM,Champion D,McArdle N

    更新日期:2019-10-01 00:00:00