Abstract:
:The aim of this study was to investigate the current published work relating to the clinical benefits of the use of systemic azithromycin as an adjunct to non-surgical periodontal therapy. A published work search of PubMed, EMBASE and Cochrane Register of Controlled Trials up to 27 April 2016 was undertaken. The large degree of heterogeneity in the types of studies, treatment protocols, test subjects, sample size and exclusion criteria indicated that the use of narrative synthesis of all relevant studies was a valid method of review. Of the 194 eligible studies, 15 were found to be of relevance. The majority of studies demonstrated an additional clinical benefit when azithromycin is used as an adjunct to non-surgical periodontal therapy, particularly in deeper pockets (≥6 mm). In conclusion, the current body of research on the adjunctive use of systemic azithromycin in non-surgical periodontal therapy suggests there is a clinical benefit and that this benefit is greatest in deeper initial pockets (≥6 mm). The findings also suggest that future studies need to be more careful in subject selection to identify susceptible patients or at risk sites, both the immunoregulatory effects and antibiotic resistance of azithromycin needs to be reported, and that study populations need to be more homogeneous.
journal_name
Aust Dent Jjournal_title
Australian dental journalauthors
O'Rourke VJdoi
10.1111/adj.12448subject
Has Abstractpub_date
2017-03-01 00:00:00pages
14-22issue
1eissn
0045-0421issn
1834-7819journal_volume
62pub_type
杂志文章,评审abstract:BACKGROUND:Periodontal treatment may be a useful adjunct to medical management of diabetes; however, oral health has not been integrated into multidisciplinary diabetes care in Australia. This study aimed to understand the needs of patients and staff at a diabetes clinic to inform a prototype of integrated dental and d...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/adj.12804
更新日期:2020-11-06 00:00:00
abstract::Nerve surgery in the maxillofacial region is confined to the trigeminal and facial nerves and their branches. The trigeminal nerve can be damaged as a result of trauma, local anaesthesia, tumour removal and implant placement but the most common cause relates to the removal of teeth, particularly the inferior alveolar ...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/j.1834-7819.2010.01216.x
更新日期:2010-06-01 00:00:00
abstract::The distances between the cephalometric points of 380 patients with complete natural dental arches were measured. A correlation between the bizygomatic, nasion-subnasal and subnasal-gnathion distances and the vertical dimension was established and a mathematical formula was derived to enable determination of both the ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1978.tb02912.x
更新日期:1978-04-01 00:00:00
abstract::It is observed clinically that some years after MOD restoration of molar and premolar teeth, cuspal failures commonly occur. The period between restoration and failure is usually from eight to fifteen years. Evidence has been found, both from observations of fractured cusps and from a mathematical model of an idealize...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1982.tb05247.x
更新日期:1982-10-01 00:00:00
abstract::Crouzon syndrome is an autosomal dominant condition characterized by craniosynostosis with associated dentofacial anomalies. This paper describes the variable clinical features in affected individuals over two generations of a family with particular reference to the dentofacial deformities and discussion of management...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1997.tb00089.x
更新日期:1997-02-01 00:00:00
abstract::In some countries the use of amalgam has been restricted, and the dental profession may be forced into using alternatives to amalgam by a combination of public opinion and legislation, including the proposal that the material be 'phased-down'. The limited research that exists as to restorative decision-making is quant...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/adj.12212
更新日期:2014-12-01 00:00:00
abstract::A case of compound composite odontome is reported. The classification and aetiology of odontomes is briefly discussed. ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1989.tb00698.x
更新日期:1989-10-01 00:00:00
abstract::It is predicted that more Australians will retain their natural dentitions into old age and their dental needs will have to be met with a wide range of dental services by dentists acting with understanding, kindness, and sympathy. The empathy to do so requires experience of appropriate delivery systems in the environm...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1982.tb04080.x
更新日期:1982-06-01 00:00:00
abstract::The patient in this report is a young boy with hypohydrotic ectodermal dysplasia. His case is exceptional in that anodontia was complete in both deciduous and permanent dentitions. A brief review of this condition is presented along with the prosthetic management of the case which emphasizes the need for regular modif...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1990.tb05873.x
更新日期:1990-04-01 00:00:00
abstract::The delivery of effective information flow through self learning, critical thinking and problem solving is one of the objectives of current curriculum development within the Dental Faculty of the University of Hong Kong. These objectives reflect a desire to encourage skills related to 'comprehension learning' and 'mea...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1992.tb00828.x
更新日期:1992-02-01 00:00:00
abstract::Haemophilia A, the most common of bleeding disorders is characterized by bruising and spontaneous bleeding into the joints but may remain undiagnosed if present in the mild form. A case is discussed where episodes of bruising and joint swelling as a child were misdiagnosed as rheumatic fever and the bleeding disorder ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1998.tb00171.x
更新日期:1998-08-01 00:00:00
abstract::Service-mix can reflect changes in demographic factors, oral health, patient demand and treatment philosophies. The aim of this study was to compare service-mix by patient age in 1988 with baseline data from 1983. A weighted, stratified random sample of dentists in Australia was surveyed by mailed questionnaire in 198...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1994.tb05569.x
更新日期:1994-10-01 00:00:00
abstract::Maxillary molar teeth may have accessory roots. The aim of this paper is to review and discuss the endodontic implications of this anatomical variation. A review of the literature was undertaken to identify studies and reported cases where accessory roots have been recorded in maxillary molar teeth. The results show t...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/j.1834-7819.2012.01678.x
更新日期:2012-06-01 00:00:00
abstract::A case of migratory abscess pointing both intraorally and extraorally at a considerable distance from the causative site is reported. The anatomy of the area leading to the formation of such an abscess is described. ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1989.tb00674.x
更新日期:1989-06-01 00:00:00
abstract::At the commencement of the 1979 Academic Year a "modular approach" to degree studies in Dentistry will be instituted at the University of Papua New Guinea. This course of studies will be comprised of four progression modules and includes a one-year programme of community service and clinical experience in a dental cli...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1978.tb02396.x
更新日期:1978-10-01 00:00:00
abstract::Cost-benefit and cost-effectiveness analyses were carried out to obtain an indication of the economic viability of the prolonged fluoride application (PFA) method. Using three year results from a clinical trial of the technique, the cost-benefit ratio has calculated as 1:2.1 and the cost-effectiveness as $3.49 per sur...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1982.tb04055.x
更新日期:1982-04-01 00:00:00
abstract::With many composite resins operators may notice a change in colour after light curing the restoration. Three types of specimen--a disc, a simulated Class III and a veneer--were made using a series of composite resins. Generally, resins became lighter or more translucent on irradiation. This was not only true for a ran...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1989.tb04625.x
更新日期:1989-04-01 00:00:00
abstract:BACKGROUND:The current retrospective cross-sectional study investigated 5-18-year treatment outcomes in subjects who did not complete a recommended course of periodontal therapy. METHODS:Sixty-five subjects who voluntarily discontinued therapy were recalled. The subjects' demographic data and dental history since disc...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/adj.12440
更新日期:2017-06-01 00:00:00
abstract::In this study, we report a very unusual case of a patient with osteomyelitis of the condyle secondary to pericoronitis of an impacted third molar. The patient was treated by removal of the impacted third molar, opening of the drainage, combined with systemic application of antibiotics for two weeks. This treatment opt...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/adj.12186
更新日期:2014-09-01 00:00:00
abstract::This review illustrates, through a series of case histories, how oral medicine insights aid the diagnosis and management of patients with excessive tooth wear. The cases reviewed are drawn from the records of 500 southeast Queensland patients referred to the author over a 12 year period. Patients most at risk of denta...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/j.1834-7819.2001.tb00288.x
更新日期:2001-12-01 00:00:00
abstract::The conversion of calcium sulphate hemihydrate powders to dihydrate by reaction with atmospheric water vapour has been re-examined gravimetrically. Storage is usually said to be safe at less than '70 per cent RH', but this is shown to be an inadequate criterion (water vapour pressure being more useful in the context) ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1990.tb05399.x
更新日期:1990-06-01 00:00:00
abstract::The ageing Australian population living in the new millennium has dental needs that are very different and more complex than those experienced by previous older adult cohorts during the twentieth century. A summary of the oral health status of older Australians is presented, together with a review of the important rel...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/j.1834-7819.2003.tb00001.x
更新日期:2003-03-01 00:00:00
abstract::The restorative dentist is often faced with difficulties in overcoming functional, cosmetic, and cleansibility requirements when replacing teeth in areas of localized alveolar ridge resorption. A case report is presented highlighting a surgical technique to correct such an alveolar ridge deficit. ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1990.tb03025.x
更新日期:1990-02-01 00:00:00
abstract:BACKGROUND:This study aimed to evaluate microhardness and chemical analysis of carious and caries-affected dentine. The hypothesis tested was that calcium:phosphorous (Ca:P) ratios correlate with microhardness values. METHODS:Four carious human third molars were sectioned through the caries lesion in the mesiodistal l...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2005.tb00368.x
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:To report the dental caries experience of preschool children within the north Brisbane region and to investigate the association between selected social and demographic variables and disease presence. METHODS:A cross-sectional sample of 2515 children aged four to six years was examined in a preschool settin...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2002.tb00547.x
更新日期:2002-12-01 00:00:00
abstract::Dental implant treatment has established benefits over traditional alternatives. Age-related changes in systemic and oral health in conjunction with social, economic and resource considerations often introduce complexities into dental implant treatment of ageing patients. When time, opportunity, discomfort and mainten...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/adj.12282
更新日期:2015-03-01 00:00:00
abstract::The effects of orthodontic tooth movement on pulpal responses are of interest to the clinician. Alterations to pulpal physiology may result in altered responses to external stimuli. This pilot project tested a small group of orthodontic patients during the early stages of treatment. Heat, cold and electrical stimuli w...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1998.tb00189.x
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:The erosive potential of wine on teeth may be modified by the buffering capacity of saliva. This potential effect was studied for three different wines in vitro and in vivo. METHODS:The buffering capacity was studied in vitro by stepwise addition of small volumes of a dry white wine, a medium sweet white wi...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2009.01124.x
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:The aim of this study was to identify the nature and causes of deterioration and failure in dental handpiece ball bearings and thus provide guidance for clinical handling for service longevity. METHODS:The bearings of 36 turbine assemblies were dismantled for visual inspection, documented using a digital ca...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/adj.12112
更新日期:2013-12-01 00:00:00
abstract::In this, the second of two papers on the relationships between dental treatment and dental health, the philosophical basis of Minimum Intervention Dentistry is presented. This approach to patient care has several distinct treatment modalities. These range from preventive measures and fissure sealants, through monitori...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1992.tb00744.x
更新日期:1992-06-01 00:00:00