Abstract:
OBJECTIVE:To discuss the clinical effects of treating secondary asthma attacks of children Mycoplasma pneumoniae with combined therapy of montelukast and azithromycin. PATIENTS AND METHODS:96 children patients diagnosed with secondary asthma attacks of Mycoplasma pneumonia were enrolled in this study. They were randomly divided into two groups: the control group (n=49) and the observation group (n=47). Patients in the control group received combined therapy using azithromycin and bronchodilators or glucocorticoid, and patients in the observation group received a combined therapy of montelukast, azithromycin and bronchodilators or glucocorticoid. The lung function indexes, T lymphocyte subpopulation, cytokines levels, positive rate of lgG and lgM, asthma control rate and recurrence rate were compared between groups before and after treatment. RESULTS:The levels of V-T, t-PTEF/t-E, MTIF/MTEF and TEF25/PTEF in both groups increased after treatment, but we observed a more significant improvement in the observation group. The CD4+ and CD4+/CD8+ levels in both groups also increased after the intervention, while the level of CD8+ decreased. The IL-10, IL-17 and TGF-β levels decreased more intensely in the observation group. DISCUSSION:The positive rate of lgG and lgM in both groups decreased significantly after the intervention. In the observation group, the asthma control rate was higher while the recurrence rate was lower. Although montelukast had little effect on improving the immune function, it was certainly beneficial for controlling the symptoms of asthma and improving the prognosis. CONCLUSIONS:Using combined therapy of montelukast and azithromycin for treating the secondary asthma attacks of children mycoplasma pneumonia can relieve immunological and inflammatory reactions and improve the lung function.
journal_name
Eur Rev Med Pharmacol Scijournal_title
European review for medical and pharmacological sciencesauthors
Gong L,Xu L,Diao M,Guo F,Bian FF,Min J,Liu R,Zhang CLsubject
Has Abstractpub_date
2016-12-01 00:00:00pages
5256-5260issue
24eissn
1128-3602issn
2284-0729journal_volume
20pub_type
杂志文章abstract:OBJECTIVE:To compare the clinical effect of two surgical methods of treating chyluria, namely, retroperitoneal laparoscopic partial dissection of adipose renal capsule plus ligation of renal pedicle lymphatic vessels and retroperitoneal laparoscopic complete dissection of adipose renal capsule plus ligation of renal pe...
journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章
doi:
更新日期:2016-12-01 00:00:00
abstract::Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "MiR-182 affects renal cancer cell proliferation, apoptosis, and invasion by regulating PI3K/AKT/mTOR signaling pathway, by J.-H. Fu, S. Yang, C.-J. Nan, C...
journal_title:European review for medical and pharmacological sciences
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doi:10.26355/eurrev_202007_21852
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abstract:OBJECTIVE:The wildfire allied environmental pollution is highly toxic and can cause significant wide-ranging damage to the regional environment, weather conditions, and it can facilitate the transmission of microorganisms and diseases. The present study aims to investigate the effect of wildfire allied pollutants, part...
journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章
doi:10.26355/eurrev_202010_23253
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abstract:OBJECTIVE:LncRNAs participate in the proliferation, apoptosis, and invasion of colorectal cancer. We aimed at investigating the uncovered effect of lncRNALUADT1 on colorectal cancer. PATIENTS AND METHODS:The relative expression level of lncRNALUADT1 in tumor specimen was tested by Real-time quantitative PCR. The assoc...
journal_title:European review for medical and pharmacological sciences
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doi:10.26355/eurrev_201804_14816
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abstract:OBJECTIVE:Indoxyl sulfate (IS) has been reported to induce endoplasmic reticulum (ER) stress in tubular cells and to inhibit the cell proliferation via ER stress and ERK/IL-6/p21 pathways. This study has investigated the effect of apigenin on IS-induced ER stress in immortalized human renal proximal tubular HK-2 cells....
journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章
doi:
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:Indoleamine 2,3-dioxygenase (IDO) initiated tryptophan degradation in the placenta has a role in the prevention of allogeneic fetus rejection by T-cells. The present study aimed to investigate the relationship between IDO and CD4+CD25+Foxp3+ T cells in pregnant mice. MATERIALS AND METHODS:The percentage of C...
journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章
doi:
更新日期:2017-04-01 00:00:00
abstract::Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by a coronavirus called SARS Coronavirus 2 (SARS-CoV-2). It has been observed that COVID-19 mainly spreads via respiratory tract, contact and digestive tract. Due to the particularity of profession, ophthalmic medical workers need to be in close conta...
journal_title:European review for medical and pharmacological sciences
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doi:10.26355/eurrev_202005_21210
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Urogenital atrophy is a degenerative process that may occur during menopause causing debilitating disorders and painful symptomatology. Estrogen therapy slows the onset of atrophy, but it requires ongoing therapy to maintain its effectiveness. To mitigate the degenerative evolutions associated with menopause,...
journal_title:European review for medical and pharmacological sciences
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doi:10.26355/eurrev_201801_14211
更新日期:2018-01-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
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更新日期:2017-05-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
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更新日期:2018-11-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
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doi:
更新日期:2015-11-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
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doi:
更新日期:2017-05-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
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journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2017-03-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
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doi:
更新日期:2015-10-01 00:00:00
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更新日期:2018-12-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章
doi:10.26355/eurrev_201711_13835
更新日期:2017-11-01 00:00:00
abstract::Diclofenac is the most widely prescribed non-steroidal anti-inflammatory drug worldwide. Data collected during the last 10 years reported a dose-duration dependent increasing of cardiovascular risk associated with the use of diclofenac, supporting the evidence of a close association with the degree of COX-2 inhibition...
journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章
doi:
更新日期:2016-10-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:European review for medical and pharmacological sciences
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doi:
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abstract:UNLABELLED:BACKGROUND, OBJECTIVES: Pancreatic cancer ranks fourth for cancer mortality for men and women in the United States. This is a particularly devastating cancer since the case-fatality proportion approaches 90% within 12 months following diagnosis. Therefore, understanding the etiology and identifying the risk ...
journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章,评审
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journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章,评审
doi:
更新日期:2016-12-01 00:00:00
abstract:INTRODUCTION:In the latest years the use of lung ultrasound is increasing in the evaluation of pleural effusions, because it makes follow-up easier and drainage more efficient by providing guidance on the most appropriate sampling site. However, no standardized approach for ultrasound-guided thoracenthesis is actually ...
journal_title:European review for medical and pharmacological sciences
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doi:
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:This paper aims at screening the common differential genes of coronary atherosclerotic heart disease (CAD) and ischemic cardiomyopathy (ICM), and to conduct pathway analysis and protein-protein interaction (PPI) network analysis for the differential genes. MATERIALS AND METHODS:The CAD and ICM datasets were ...
journal_title:European review for medical and pharmacological sciences
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更新日期:2018-06-01 00:00:00
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更新日期:2017-07-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
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doi:10.26355/eurrev_201912_19761
更新日期:2019-12-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
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更新日期:2011-09-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
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更新日期:2015-10-01 00:00:00
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journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2015-04-01 00:00:00