Abstract：
:There are many tools for differentiating between multiple system atrophy with predominant parkinsonian features (MSA-P) and Parkinson's disease (PD). These include middle cerebellar peduncle (MCP) width, apparent diffusion coefficient (ADC) value of the putamen and cerebellum, and (123)I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy images. We aimed to directly compare the above-mentioned methods, and to determine the optimal tool for differential diagnosis. Eleven patients with MSA-P and 36 patients with PD were enrolled. Of these, 7 patients with MSA-P and 14 patients with PD were chosen as background-matched subjects. We measured MCP width, ADC value of the putamen and cerebellum, and MIBG myocardial scintigraphy images. Area under curve (AUC) of receiver operating characteristic (ROC) was assessed to compare the above-mentioned methods. MCP width and ADC value of the putamen may be helpful for differentiating between MSA-P and PD relative to other methods in background-matched patients (MCP, AUC=0.95; putamen ADC, AUC=0.88; cerebellar ADC, AUC=0.70; MIBG, AUC=0.78). Similar AUCs were seen in all patients with different backgrounds. Our findings suggested that MCP width and ADC value of the putamen could be superior to ADC value of the cerebellum and MIBG uptake for differentiating between MSA-P and PD.
journal_name
J Neurol Scijournal_title
Journal of the neurological sciencesauthors
Sako W,Abe T,Murakami N,Miyazaki Y,Izumi Y,Harada M,Kaji Rdoi
10.1016/j.jns.2016.06.061subject
Has Abstractpub_date
2016-09-15 00:00:00pages
104-8eissn
0022-510Xissn
1878-5883pii
S0022-510X(16)30392-6journal_volume
368pub_type
杂志文章abstract：OBJECTIVE:The etiology and outcome of pediatric stroke differs in different geographical regions and there is no comprehensive study from India. This study evaluates the etiology, type and predictors of outcome of pediatric stroke from Northern India. METHODS:79 stroke patients aged 1month to 18years managed during 20...
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pub_type： 杂志文章
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journal_title：Journal of the neurological sciences
pub_type： 杂志文章,评审
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pub_type： 杂志文章,meta分析
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更新日期：2014-01-15 00:00:00
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journal_title：Journal of the neurological sciences
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/0022-510x(90)90131-6
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journal_title：Journal of the neurological sciences
pub_type： 杂志文章
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