Dental pulp mesenchymal stem/stromal cells labeled with iron sucrose release exosomes and cells applied intra-nasally migrate to intracerebral glioblastoma.

abstract：:The objective of the present study was to evaluate clinical condition and results of surgical treatment of patients with typical and atypical bronchial carcinoids. The study was based on retrospective analysis of a total of 96 patients (mean age 47.3 year, age range 21-76, 44 men and women 52), who were surgically tre...

journal_title：Neoplasma

authors： Fiala P,Petrásková K,Cernohorský S,Kinkor Z,Krepela E,Zatloukal P

更新日期：2003-01-01 00:00:00

abstract：:Cytembena has been shown to undergo a rapid addition reaction with a number of thiol compounds, including glutathione and cysteine, resulting in alkylation of the sulphur. Administration of Cytembena to Yoshida sarcoma cells and to L1210 leukemia cells resulted in a loss of titratable thiol groups within the cells, th...

journal_title：Neoplasma

authors： Jackson RC,Taylor GA,Harrap KR

更新日期：1976-01-01 00:00:00

abstract：:Projections for the incidence of all and selected major sites of cancer in the cities of Cracow and Bratislava were constructed for each year of the period 1978-1982 on the basis of data observed in the years 1968-1977. More or less increasing of unchanging trends were predicted for the malignant neoplasms of bladder,...

journal_title：Neoplasma

authors： Pawłega J,Plesko I,Dimitrova E

更新日期：1982-01-01 00:00:00

abstract：:Cell surface and calf serum proteins were released in vitro from cultured virus-transformed, chemically transformed and normal rat embryo fibroblasts in 0.2 M urea containing serum-free culture medium. Fibronectin (LETS protein) was found in considerably higher amount in medium from normal rat embryo fibroblasts than ...

journal_title：Neoplasma

authors： Duraj J,Chorváth B,Simkovic D

更新日期：1979-01-01 00:00:00

abstract：:Phorbol ester (PMA) induced decrease in cell surface expression of CD4 antigen was potentiated on human monoblastoid cell line U-937 cultured and induced in protein-free culture medium. Down-regulation of the CD4 antigen was partially inhibited by the isoquinoline protein kinase inhibitor H7 and unaffected by the calm...

journal_title：Neoplasma

authors： Hunáková L,Sedlák J,Chorváth B

更新日期：1993-01-01 00:00:00

abstract：:The paper deals with some results of work done in the USSR to establish maximal allowable doses (MAC) for the carcinogenic hydrocarbon benza(a)pyrene in human environment. At the same time it is a brief review of some discussions on this item which took place in USSR and on the international level. ...

journal_title：Neoplasma

authors： Shabad LM

更新日期：1975-01-01 00:00:00

abstract：:Hepatocellular carcinoma is the most common primary malignancy of the liver. The chemotherapeutic drug cisplatin is widely used for advanced liver cancer. However, the development of cisplatin resistance in cancer cells, which is related with the decreased cellular susceptibility to apoptosis, results in a major limit...

journal_title：Neoplasma

authors： Zhang B,Cao K,Liu Z,Shan W,Wen Q,Wang R

更新日期：2019-05-11 00:00:00

abstract：:Active human serum manifests a tumoricide effect against cells of the Ehrlich ascites tumor. Sera of patients with Ca ventriculi show a higher effect than those of patients with a chronic streptococcal disorder, in comparison with intact subjects. This tumorcide effect is depressed by Varidase, the degree of depressio...

journal_title：Neoplasma

authors： Mikolásek J

更新日期：1975-01-01 00:00:00

abstract：:The effect of oxoplatinum on blastic transformation of human peripheral blood mononuclear cells (PBMC) was monitored following phytohemagglutinin (PHA) stimulation. The results were compared with those published in part III of the present work as well as with the effect of cisplatinum and carboplatinum on the blastic ...

journal_title：Neoplasma

authors： Kanková-Vancurová M,Procházková J

更新日期：1991-01-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-alpha) a proinflammatory cytokine with multiple actions was first identified for its anticancer activity. However, TNF-alpha has a beneficial function in activation of host defense, its uncontrolled production can lead to pathological consequences. At the cellular level, it is able to ...

journal_title：Neoplasma

authors： Szatmáry Z

更新日期：1999-01-01 00:00:00

abstract：UNLABELLED:The growth-regulated oncogene α (GROα) , which is also designated as CXC chemokine ligand 1 (CXCL1), was first identified as an autocrine growth factor in human malignant melanoma. It is involved in tumor development and invasion, and is highly expressed in various human cancers. However, little is known abo...

journal_title：Neoplasma

authors： Han L,Liu W,Chen Y,Wu H,Zhang Y,Jiang B

更新日期：2015-01-01 00:00:00

abstract：:Puerarin has recently been demonstrated to play anti-cancer roles in a series of human cancers, including non-small cell lung cancer (NSCLC), possibly through regulation of cancer-related microRNAs (miRNAs). The purpose of the present study was to further investigate the detailed role and underlying mechanism of puera...

journal_title：Neoplasma

authors： Huang SR,Jin SS,Xu B,Wang RP

更新日期：2020-11-01 00:00:00

abstract：:The relationship of pretreatment immunologic status in terms of skin tests to prognosis within stages was studied in 152 breast cancer patients. DNCB and PPD testing was used. As for DNCB, no relationship was found at early stages of the disease. In locoregionally advanced disease, patients with stronger test grades h...

journal_title：Neoplasma

authors： Munzarová M,Kovarík J,Hlávková J,Popelínský L,Lauerová L

更新日期：1985-01-01 00:00:00

abstract：:We evaluated the prognostic impact of chromosomal abnormalities as detected by interphase fluorescence in situ hybridization (iFISH) in 86 chronic lymphocytic leukemia (CLL) patients. Overall, 39 of 86 (45%) patients displayed one (35%) or more (10%) chromosomal abnormalities, del13q (31%) being more frequently detect...

journal_title：Neoplasma

authors： Giertlova M,Hajikova M,Vaskova J,Kafkova A,Stecova N,Mirossay L,Karabinos A,Tothova E,Sarissky M

更新日期：2011-01-01 00:00:00

abstract：:The influence of 13-cis-retinoic acid on the light-caused injury of hematoporphyrin-pretreated nontransformed 10 T1/2 fibroblasts and N2a neuroblastoma cells was investigated. Retinoid reduced the percentage of damaged cells as assessed by the plating efficiency assay. N2a neuroblastoma cells were found to be better p...

journal_title：Neoplasma

authors： Szaniawska B,Janik P,Ostrowski J,Graczyk A

更新日期：1988-01-01 00:00:00

abstract：:Twenty-nine bilateral breast carcinoma patients were analyzed retrospectively. The incidence of bilateral carcinoma of the breast among unilateral breast cancer patients was approximately 2.4%. Median age was 46 years at the time of first cancer diagnosis (range 26-69 years). The majority of the lesions were invasive ...

journal_title：Neoplasma

authors： Engin K

更新日期：1994-01-01 00:00:00

abstract：:Very few studies have determined the prognostic value of interim and restaging PET/CT in patients with Hodgkin lymphoma using current standard of care therapy outside clinical trials. We analyzed the effect of the results of interim and restaging PET/CT on the survival (overall- and relapse-free) in patients who recei...

journal_title：Neoplasma

authors： Miltenyi Z,Barna S,Garai I,Simon Z,Jona A,Magyari F,Gergely M,Nagy Z,Keresztes K,Pettendi P,Illes A

更新日期：2015-01-01 00:00:00

abstract：:The relationship between malignant tumors and blood coagulation disorders is generally well known. The authors studied blood coagulation in patients with colorectal cancer and evaluated some prothrombotic markers. The authors analyzed by latex-aglutination method, ProC Global test, Asserachrom PAI-1 test and Enzygnost...

journal_title：Neoplasma

authors： Mytnik M,Stasko J

更新日期：2011-01-01 00:00:00

abstract：:NAT2 as phase II enzyme is involved in the detoxification/activation of various drugs, environmental substances and carcinogenic compounds. A genotyping approach has been used to investigate NAT2 genotype with putative relevance in lung cancer in population of 110 Slovak-Caucasians patients and 167 non-malignant indiv...

journal_title：Neoplasma

authors： Habalová V,Salagovic J,Kalina I,Stubna J

更新日期：2005-01-01 00:00:00

abstract：:5-Azacytidine administered to male mice prior to mating resulted in their decreased fertility and in the loss of offsprings at different periods of embryonic and postnatal development. The drug interfered with mature spermatozoa and spermatids; considerable distortion of cellular associations in seminiferous epitheliu...

journal_title：Neoplasma

authors： Seifertová M,Veselý J,Cihák A

更新日期：1976-01-01 00:00:00

abstract：:Helicase POLQ-like (HELQ), an ATP-dependent 3'-5' DNA helicase, plays pivotal roles in DNA processing, such as DNA replication, recombination and repair. The recent discovery of HELQ in mouse model and human cancer cell reveal that genetic alteration of HELQ is involved in cancer susceptibility and subfertility. Here ...

journal_title：Neoplasma

authors： Han X,Zhao L,Li X

更新日期：2016-01-01 00:00:00

abstract：:Molecular genetic studies have revealed mutations in a number of oncogenes and tumor suppressor genes in lung cancer. The bcl-2 gene product (bcl-2 protein) is implicated in oncogenesis by its ability to prolong cell death through the inhibition of apoptosis. We investigated expression of bcl-2 in 84 resected human no...

journal_title：Neoplasma

authors： Laudanski J,Chyczewski L,Niklińska WE,Kretowska M,Furman M,Sawicki B,Nikliński J

更新日期：1999-01-01 00:00:00

abstract：:Application of hyperimmune rabbit antisera against mouse lymphomas (6C3HED lymphoma, NK lymphoma) or against rat leukemic cells (RBA-34-Le leukemia) caused a considerable degree of lymphocyte depletion in hamsters. ...

journal_title：Neoplasma

authors： Oravec C,Ondrus B

更新日期：1977-01-01 00:00:00

abstract：:CD147, a widely expressed cell surface glycoprotein in cancer, is associated with tumor invasiveness and chemotherapy resistance. Recently, CD147 is also regarded as a potential therapeutic target for cancer therapy. The aim of the study was to investigate CD147 expression in non-small cell lung cancer (NSCLC), and ev...

journal_title：Neoplasma

authors： Zeng HZ,Qu YQ,Liang AB,Deng AM,Zhang WJ,Xiu B,Wang H,Wang H

更新日期：2011-01-01 00:00:00

abstract：:Cancer cells share numerous characteristics with pluripotent stem cells which develop normally, contributing to the tumor cell plasticity. So we investigated the effect of human embryonic germ cells (hEGCs) on SKOV3 cells. We examined the efficacy of hEGCs through coculturing SKOV3 with hEGCs, detecting tunel apoptosi...

journal_title：Neoplasma

authors： Song X,Kong B,Li D,Yang Q

更新日期：2009-01-01 00:00:00

abstract：:Heat Shock proteins 70 (Hsp70) is a family of highly conserved molecules that maintain the function of crucial cellular pathways during stress. Hsp70 derived from tumor cells is bound with tumor antigenic peptides from the diverse antigen cytosolic pool. Tumor-derived Hsp70 preparations after ex vivo administration pe...

journal_title：Neoplasma

authors： Kumar S,Deepak P,Acharya A

更新日期：2009-01-01 00:00:00

abstract：:Increasing evidences have proved that circular RNAs (circRNAs), identified as a specific kind of non-coding RNAs, play a potential critical role in tumorigenesis including prostate cancer. However, the function of circRNAs in human prostate cancer remain largely unknown. In this study, we demonstrated that the express...

journal_title：Neoplasma

authors： Jiang H,Lv DJ,Song XL,Wang C,Yu YZ,Zhao SC

更新日期：2020-01-01 00:00:00

abstract：:The levels of nicotinamide adenine dinucleotide (NAD) and NADH in blood of patients with cancer in various stages of development as well as their modification after glucose administration were determined in 188 respectively 77 cases. NAD was significantly decreased in patients with cervix and breast carcinoma but unal...

journal_title：Neoplasma

authors： Comes R,Mustea I

更新日期：1976-01-01 00:00:00

abstract：:Serum concentration of alpha1-proteinase inhibitor (alpha1-PI) was determined by nephelometric method in forty seven patients with liver cirrhosis (LC) and fifteen patients with hepatocellular carcinoma (HCC). Our data show an increase in the concentration of alpha1-PI in the group with decompensated LC by 17% and in ...

journal_title：Neoplasma

authors： Dabrowska M,Mantur M,Panasiuk A,Prokopowicz J

更新日期：1997-01-01 00:00:00

abstract：:An actin-binding protein filamin A connects the actin filament network to cell membrane receptors, and acts as a scaffold for various signaling pathways related to cancer growth and progression. Recently, it has been reported that filamin A is required for efficient regulation of early stages of DNA repair process. Mo...

journal_title：Neoplasma

authors： Gachechiladze M,Skarda J,Janikova M,Mgebrishvili G,Kharaishvili G,Kolek V,Grygarkova I,Klein J,Poprachova A,Arabuli M,Kolar Z

更新日期：2016-01-01 00:00:00