Abstract:
:Methadone maintenance therapy has been found to be an effective harm reduction treatment for opioid use disorder. However evidence of its benefits over a longer duration of treatment is limited as most studies focus on its short term benefits. As methadone maintenance therapy reaches a decade since its implementation in Malaysia, this study sought to examine the effectiveness of methadone treatment, change in quality of life among patients since entry to methadone treatment, as well as factors predicting the magnitude of change in quality of life. This study found that methadone maintenance therapy was effective in reducing heroin use, injecting practices and crime, and in improving in social functioning and physical symptoms, but not in reducing sex-related HIV risk-taking behavior. Though patients had a significantly better quality of life at follow-up than at entry to methadone maintenance therapy, the improvement in quality of life was not significantly greater as the duration of treatment increased. Age above 50 years old, human immunodeficiency virus (HIV) positive status and physical symptoms predicted a poorer improvement in quality of life between baseline and follow-up. On the other hand, patients with hepatitis B showed a greater improvement in quality of life in the social relationships domain compared to patients without hepatitis B. In conclusion, methadone maintenance therapy is an effective treatment for opioid use disorder and improves quality of life but its benefits in further improving quality of life beyond a decade of treatment need further evaluation.
journal_name
J Subst Abuse Treatjournal_title
Journal of substance abuse treatmentauthors
Teoh Bing Fei J,Yee A,Habil MH,Danaee Mdoi
10.1016/j.jsat.2016.07.006subject
Has Abstractpub_date
2016-10-01 00:00:00pages
50-6eissn
0740-5472issn
1873-6483pii
S0740-5472(16)30009-5journal_volume
69pub_type
杂志文章abstract::We review the problems unique to the diagnosis and treatment of patients who suffer both major mental illness and alcohol/drug abuse. We describe the experience and the approach evolved in the Special Treatment Team, a State Hospital unit that has specialized in this work. We discuss in detail the assessment and stabi...
journal_title:Journal of substance abuse treatment
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journal_title:Journal of substance abuse treatment
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pub_type: 杂志文章,多中心研究
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journal_title:Journal of substance abuse treatment
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journal_title:Journal of substance abuse treatment
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journal_title:Journal of substance abuse treatment
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doi:10.1016/j.jsat.2019.04.004
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