Abstract:
:High resolution is important for sensitive detection of subtle distortions of retinal morphology at an early stage of eye diseases. We demonstrate virtually structured detection (VSD) as a feasible method to achieve in vivo super-resolution ophthalmoscopy. A line-scanning strategy was employed to achieve a super-resolution imaging speed up to 127 ?? frames / s with a frame size of 512 × 512 ?? pixels . The proof-of-concept experiment was performed on anesthetized frogs. VSD-based super-resolution images reveal individual photoreceptors and nerve fiber bundles unambiguously. Both image contrast and signal-to-noise ratio are significantly improved due to the VSD implementation.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Liu C,Zhi Y,Wang B,Thapa D,Chen Y,Alam M,Lu Y,Yao Xdoi
10.1117/1.JBO.21.12.120502subject
Has Abstractpub_date
2016-12-01 00:00:00pages
120502issue
12eissn
1083-3668issn
1560-2281pii
2594508journal_volume
21pub_type
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