Abstract:
PURPOSE:To report the ocular findings, systemic hematologic parameters, and treatment outcomes of patients with recurrent central retinal vein occlusions (CRVO). METHODS:A retrospective analysis of eyes that developed recurrent CRVO was performed. Key exclusion criteria were follow-up of less than six months after the recurrence, incomplete documentation, and recurrent macular edema in an eye with a CRVO but without evidence of increased superficial hemorrhage or disc edema (recurrent CRVO). Collected data included demographic information, history of presenting illness including the previous CRVO, ocular and systemic co-morbidities, and clinical examination findings that included visual acuities and imaging details from the time of initial CRVO diagnosis until the final examination. RESULTS:Thirteen eyes of 12 subjects with recurrent CRVO were evaluated. The mean age of the patients was 63 years (range: 42 to 79 years). The mean interval between treatment of the initial CRVO and the onset of the recurrent CRVO was 9.0 ± 9.3 months. The visual acuity declined by approximately eight lines at the time of recurrence. Treatment with vascular endothelial growth factor inhibitors and corticosteroids significantly improved mean central macular thickness (CMT) from the time of recurrence until the final examination (808 ± 169 vs. 511 ± 302 µm; P = 0.004), but failed to change visual acuity (1.28 ± 0.31 logMAR vs. 1.24 ± 0.43 logMAR; P = 0.8). No uncontrolled systemic risk factors were associated with recurrences. CONCLUSION:Recurrent CRVO in the same eye occurs infrequently and may not be associated with an uncontrolled systemic disease. Despite multimodal therapy, most eyes do not recover vision to the pre-recurrence level.
journal_name
Semin Ophthalmoljournal_title
Seminars in ophthalmologyauthors
Chhablani J,Stewart M,Paulose R,Gallego-Pinazo R,Dolz-Marco Rdoi
10.1080/08820538.2016.1188130subject
Has Abstractpub_date
2018-01-01 00:00:00pages
191-197issue
2eissn
0882-0538issn
1744-5205journal_volume
33pub_type
杂志文章,多中心研究abstract:PURPOSE:To describe a case of cotton wool spots associated with interferon beta-1a treatment. METHODS:Observational case report. RESULTS:A 40-year-old man with a history of multiple sclerosis was on interferon beta-1a. He presented with cotton wool spots on fundus exam, which resolved and then recurred all while on t...
journal_title:Seminars in ophthalmology
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doi:10.1080/08820530601182725
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journal_title:Seminars in ophthalmology
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abstract::Age-related macular degeneration (AMD) is a common cause of legal blindness in the developed countries in people older than 50 years of age. AMD complicated by choroidal neovascular membranes (CNV) accounts for 12% of AMD, but for 88% of legal blindness cases. Because of the progressive aging of the population, it is ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
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abstract:PURPOSE:To evaluate the results of scleral-fixated posterior chamber intraocular lenses (SFIOL) in pediatric and adult patients. METHODS:We carried out a retrospective analysis of 129 eyes of 120 patients (adult group, n = 96; pediatric group, n = 24) who underwent SFIOL implantation. Outcome measures were indications...
journal_title:Seminars in ophthalmology
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journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
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journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
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journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
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更新日期:1998-03-01 00:00:00
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journal_title:Seminars in ophthalmology
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doi:10.3109/08820538.2015.1090611
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journal_title:Seminars in ophthalmology
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abstract::Syphilis is a sexually transmitted, chronic, systemic infection caused by the spirochete Treponema pallidum. If left untreated, the disease progresses through four stages, with the potential to cause significant morbidity to any major organ of the body. Frequent syphilitic ocular manifestations, which can occur at any...
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journal_title:Seminars in ophthalmology
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journal_title:Seminars in ophthalmology
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journal_title:Seminars in ophthalmology
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abstract::Acute acquired comitant esotropia (AACE) is characterized by a sudden-onset eye misalignment with an equal angle of deviation in all fields of gaze. This form of esotropia is distinct from common forms of childhood esotropia, such as infantile esotropia and accommodative esotropia, in the rapid tempo and typically lat...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
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abstract::Management of angle closure glaucoma requires an understanding of the underlying pathophysiologic mechanisms. Treatment is aimed at eliminating pupillary block and other causes of angle closure, re-opening the angle, and preventing further damage to the optic nerve by lowering intraocular pressure. Medical therapy pla...
journal_title:Seminars in ophthalmology
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journal_title:Seminars in ophthalmology
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更新日期:2019-01-01 00:00:00
abstract::Currently, there is no proven drug treatment for dry age-related macular degeneration (AMD). Several different treatment strategies are being investigated, including complement inhibition, neuroprotection, and visual cycle inhibitors, and novel clinical trial endpoints are being explored. Studies have identified genet...
journal_title:Seminars in ophthalmology
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更新日期:2011-05-01 00:00:00
abstract:PURPOSE:To evaluate the outcomes of patients with vitreomacular traction syndrome (VMT) treated with triamcinolone acetonid (TA) assisted 23-gauge (23-G) transconjunctival sutureless vitrectomy. METHODS:Restrospective, case series. The medical charts of 13 eyes of 13 consecutive patients with VMT who underwent 23-gaug...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
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