Abstract:
:Implantable cardiac pacing and defibrillation devices are effective and commonly used therapies for patients with cardiac rhythm disorders. Because device implantation is not easily reversible, as well as the high healthcare costs inherent in device use, a clear understanding of the clinical benefits relative to costs is essential for both appropriate clinical use and rational policy making. Cardiac implantable electronic devices (CIEDs) have been among the best-investigated therapies in medicine; these devices have been the topic of numerous clinical and economic evaluations during the past 30 years. However, many important questions remain unclarified. We review the evidence supporting the clinical benefits of CIEDs, including effectiveness in extending survival as well as improving quality of life. We also summarize the economic studies that have investigated costs associated with these devices and their overall cost effectiveness, and we highlight important potential areas for future research.
journal_name
Annu Rev Medjournal_title
Annual review of medicineauthors
Groeneveld PW,Dixit Sdoi
10.1146/annurev-med-043015-123540subject
Has Abstractpub_date
2017-01-14 00:00:00pages
1-13eissn
0066-4219issn
1545-326Xjournal_volume
68pub_type
杂志文章,评审abstract::The number of patients with end-stage heart failure (HF) continues to increase over time, but there has been little change in the availability of organs for cardiac transplantation, intensifying the demand for left ventricular assist devices (LVADs) as a bridge to transplantation. There is also a growing number of pat...
journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
pub_type: 杂志文章,评审
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
pub_type: 杂志文章,评审
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journal_title:Annual review of medicine
pub_type: 杂志文章
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更新日期:2002-01-01 00:00:00
abstract::The incretin-based therapies, dipeptidyl peptidase-4 (DPP4) inhibitors and glucagon-like peptide-1 (GLP-1) analogs, are important new classes of therapy for type 2 diabetes mellitus (T2DM). These agents prolong the action of the incretin hormones, GLP-1 and glucose-dependent insulinotropic polypeptide (GIP), by inhibi...
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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abstract::Highly specialized mechanisms are required for transporting cobalamin (vitamin B12) into and out of mammalian cells. This review describes the key role of the cobalamin-binding proteins in meeting the stringent requirements for transport of this essential nutrient. Also summarized are the various defects capable of im...
journal_title:Annual review of medicine
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journal_title:Annual review of medicine
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abstract::Allergic bronchopulmonary aspergillosis (ABPA) is a syndrome seen in patients with asthma and cystic fibrosis. It is characterized by chronic colonization of the airways with a ubiquitous fungus, Aspergillus fumigatus. The clinical expression of ABPA results from the complex interaction of chronic colonization of the ...
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journal_title:Annual review of medicine
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abstract::Brain imaging is increasingly applied in psychiatry, both for clinical evaluation and as a research tool. Computerized tomography (CT) and magnetic resonance imaging (MRI) have documented that structural brain abnormalities occur in some types of psychiatric patients, particularly those who suffer from schizophrenia. ...
journal_title:Annual review of medicine
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