Abstract:
:The advances in genetics and biochemistry that have taken place over the last 10 years led to significant advances in experimental and clinical immunology. In turn, this has led to the development of new mathematical models to investigate qualitatively and quantitatively various open questions in immunology. In this study we present a review of some research areas in mathematical immunology that evolved over the last 10 years. To this end, we take a step-by-step approach in discussing a range of models derived to study the dynamics of both the innate and immune responses at the molecular, cellular and tissue scales. To emphasise the use of mathematics in modelling in this area, we also review some of the mathematical tools used to investigate these models. Finally, we discuss some future trends in both experimental immunology and mathematical immunology for the upcoming years.
journal_name
Bull Math Bioljournal_title
Bulletin of mathematical biologyauthors
Eftimie R,Gillard JJ,Cantrell DAdoi
10.1007/s11538-016-0214-9subject
Has Abstractpub_date
2016-10-01 00:00:00pages
2091-2134issue
10eissn
0092-8240issn
1522-9602pii
10.1007/s11538-016-0214-9journal_volume
78pub_type
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