Adult T-cell leukemia/lymphoma and cutaneous T-cell lymphoma. Are they related?

Abstract:

:Comparative studies were performed on clinical and laboratory features of four patients with different types of T-cell lymphoma of the skin; adult T-cell leukemia/lymphoma (ATLL), Sézary syndrome, mycosis fungoides, and Ki-1-positive lymphoma. All neoplastic cells studied showed a helper-inducer T-cell phenotype. A Ki-1-positive lymphoma is distinct from other types of cutaneous lymphomas because of unique morphologic and phenotypic features. Clonal proliferation of lymphocytes infected by human T-cell lymphotrophic virus (HTLV)-1 distinguishes ATLL from other T-cell lymphomas of the skin, especially in the endemic area of ATLL. From the pathogenic point of view, ATLL should not be included in a group with mycosis fungoides and Sézary syndrome.

journal_name

Int J Dermatol

authors

Yamada M,Takigawa M,Iwatsuki K,Inoue F

doi

10.1111/j.1365-4362.1989.tb01329.x

subject

Has Abstract

pub_date

1989-03-01 00:00:00

pages

107-13

issue

2

eissn

0011-9059

issn

1365-4632

journal_volume

28

pub_type

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