Abstract:
OBJECTIVES:We summarized comparative studies of MitraClip versus surgical repair for mitral regurgitation (MR) with a systematic literature search and meta-analytic estimates. METHODS:MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were searched through June 2016. Eligible studies were randomized controlled or observational comparative studies of MitraClip versus surgical repair enrolling patients with MR and reporting early (30-day or in-hospital) or late (≥6-month including early) all-cause mortality. For each study, data regarding all-cause mortality and incidence of recurrent >2+ MR in both groups were used to generate odds ratios (ORs). Alternatively, ORs or hazard ratios (HRs) for mortality and recurrent MR themselves were directly abstracted from each study. RESULTS:Eight reports of 7 studies comparing MitraClip with surgical repair enrolling a total of 1015 patients with MR were identified and included. Pooled analyses demonstrated significantly higher age and logistic European System of Cardiac Operative Risk Evaluation and significantly lower ejection fraction in the MitraClip than surgical repair group, no significant difference in rate of women and patients with New York Heart Association functional class of >II, no statistically significant difference in early- (OR, 0.54; p=0.08) and late-mortality (HR/OR, 1.17; p=0.46), and significantly higher incidence of recurrent MR in the MitraClip than surgical repair group (HR/OR, 4.80; p<0.00001). CONCLUSIONS:In patients with MR, the MitraClip procedure achieves similar survival to surgical MV repair despite higher risk profiles. Recurrent MR, however, occurs more frequently (4.8-fold) after the MitraClip than surgical repair.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Takagi H,Ando T,Umemoto T,ALICE (All-Literature Investigation of Cardiovascular Evidence) Group.doi
10.1016/j.ijcard.2016.11.153subject
Has Abstractpub_date
2017-02-01 00:00:00pages
289-294eissn
0167-5273issn
1874-1754pii
S0167-5273(16)33613-0journal_volume
228pub_type
杂志文章,meta分析,评审abstract:BACKGROUND:Exertional dyspnea is a frequent limiting symptom in patients with chronic heart failure. Furthermore, dyspnea and a plateau in VO(2) (oxygen consumption) at peak exercise often co-exist in chronic heart failure, especially in patients with severe regurgitant valvular heart disease (RVHD), their relevance to...
journal_title:International journal of cardiology
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abstract::Coronary endothelial dysfunction has been demonstrated in patients with symptomatic heart failure. Furthermore the endothelium has been implicated in the pathogensis of cardiomyopathy in patients with normal coronary angiograms and no other known causes of heart failure. Herein we describe an asymptomatic patient with...
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journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析
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abstract::A 79 year old man was admitted to the hospital with increased breathlessness and fatigue on minimal exertion, and this since a few weeks. Transthoracic and transesophageal echocardiography, followed by cardiovascular magnetic resonance imaging, demonstrated a cardiac pseudoaneurysm connected with both ventricular cavi...
journal_title:International journal of cardiology
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journal_title:International journal of cardiology
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doi:10.1016/0167-5273(91)90017-j
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abstract:OBJECTIVE:To explore the value of transthoracic and right heart contrast echocardiography in the diagnosis of coronary sinus septal defect (CSSD), also known as unroofed coronary sinus. METHODS:The echocardiographic characteristics of 20 patients with CSSD who underwent surgery in our hospital between October 1999 and...
journal_title:International journal of cardiology
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
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doi:10.1016/j.ijcard.2018.05.113
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
pub_type: 信件
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2009.05.046
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2010-10-08 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2005-09-30 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.07.038
更新日期:2017-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-04-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2014.10.029
更新日期:2014-12-20 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.03.056
更新日期:2006-03-08 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2017-12-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2006-10-10 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2016-04-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2014.04.181
更新日期:2014-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2017-03-15 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2019-04-15 00:00:00
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pub_type: 杂志文章,评审
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更新日期:1988-10-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2009.03.054
更新日期:2010-09-03 00:00:00