Abstract:
:The treatment paradigm in glaucoma classically starts with exhausting all medical therapy prior to proceeding with laser or incisional surgery, although laser-first and surgery-first strategies have been explored in randomized clinical trials. Although glaucoma drops are proven to work well to lower intraocular pressure, slow the conversion from ocular hypertension, and slow the progression of disease in early open angle glaucoma, adherence to treatment is likely optimum in the randomized clinical trials that support these claims. In real-world scenarios, medical therapy often fails and practitioners are forced to proceed with more invasive treatment modalities to slow the progression of this blinding disease. This review aims to take an evidence-based approach to study the risk factors for poor adherence in glaucoma patients, to determine whether poor adherence is, in fact, associated with worse outcomes, and to seek potential strategies to improve adherence in these patients.
journal_name
Semin Ophthalmoljournal_title
Seminars in ophthalmologyauthors
Joseph A,Pasquale LRdoi
10.1080/08820538.2016.1228406subject
Has Abstractpub_date
2017-01-01 00:00:00pages
86-90issue
1eissn
0882-0538issn
1744-5205journal_volume
32pub_type
杂志文章,评审abstract::Normal tension glaucoma (NTG) is a common form of open-angle glaucoma that can lead to significant visual morbidity. There has been considerable debate as to whether NTG fits within the spectrum of primary open-angle glaucoma (POAG). The relative roles of intraocular pressure and pressure-independent factors in this d...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2013.771202
更新日期:2013-05-01 00:00:00
abstract::Currently, there is no proven drug treatment for dry age-related macular degeneration (AMD). Several different treatment strategies are being investigated, including complement inhibition, neuroprotection, and visual cycle inhibitors, and novel clinical trial endpoints are being explored. Studies have identified genet...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2011.577132
更新日期:2011-05-01 00:00:00
abstract::Recurrent herpes stromal keratitis (HSK) is one of the leading causes of blindness in the developed world. Cyokines characteristic of Th1 cells (in particular IFN-γ and IL-2) have been shown to dominate in HSK in addition to mechanisms by nonspecific, antigen-independent effector cells such as neutrophils, basophils, ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2011.588659
更新日期:2011-07-01 00:00:00
abstract::The management of a patient with a suspected posterior communicating artery aneurysm is discussed with emphasis on neuroimaging including magnetic resonance angiography (MRA), computed tomography angiography (CTA) and intra-arterial digital subtraction angiography (DSA). This paper underscores the advantages and disad...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820530801978534
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:Amblyopia is a leading cause of low vision and warrants timely management during childhood. We performed a literature review of the management of amblyopia and potential risk factors for amblyopia. METHODS:Literature review of the management of amblyopia and risk factors for amblyopia. RESULTS:Common amblyopi...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820538.2016.1228408
更新日期:2017-01-01 00:00:00
abstract::Cosmetic eyelid surgery has benefited from the use of the carbon dioxide laser. The short pulsed laser cuts through tissue with limited surrounding thermal damage, resulting in incisions that heal with minimal scarring comparable to traditional cold steel methods. The laser provides excellent hemostasis, which shorten...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820539809066084
更新日期:1998-09-01 00:00:00
abstract::Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly, and the advent of anti-vascular endothelial growth factor agents (VEGF) has revolutionized treatment for neovascular AMD. Two of the most popular anti-VEGF agents, ranibizumab (Lucentis; Genentech/Roche) and bevacizumab (Avastin; ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2016.1154174
更新日期:2016-01-01 00:00:00
abstract::Transpupillary thermotherapy (TTT) has been suggested as a putative treatment for choroidal neovascularization (CNV) in age-related macular degeneration (AMD). This prospective study comprised 66 consecutive patients referred for exudative AMD with predominantly occult subfoveal CNV. Based on fluorescein angiography, ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1076/soph.16.2.90.4210
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVE:To compare the effect of 10% phenylephrine (PE) instillation and manual elevation (ME) on the upper eyelid position of the tested eye and the contralateral eye in patients with involutional blepharoptosis (IB). METHODS:IB patients were submitted to two tests followed by observation of the effect on the contr...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2015.1045152
更新日期:2017-01-01 00:00:00
abstract::Lymphomatoid papulosis (LyP) is a chronic papulonecrotic or papulonodular skin disease, with histological features suggestive of malignant lymphoma. It was originally described by Macauley (1968) as a "self-healing paradoxical eruption, histologically malignant but clinically benign." Unless accompanied by systemic ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2012.680643
更新日期:2013-01-01 00:00:00
abstract::The current management of acute post-operative endophthalmitis relies on microbial confirmation, intravitreal antibiotics, and vitrectomy. The endophthalmitis vitrectomy study (EVS) demonstrated that systemic antibiotics are not necessary in post-cataract/secondary intraocular lens (IOL) acute bacterial endophthalmiti...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1076/soph.18.3.109.29804
更新日期:2003-09-01 00:00:00
abstract:PURPOSE:To analyze the ability of Spectralis optical coherence tomography (OCT) to detect multiple sclerosis (MS) and to distinguish MS eyes with antecedent optic neuritis (ON). To analyze the capability of artificial neural network (ANN) techniques to improve the diagnostic precision. METHODS:MS patients and controls...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2013.810277
更新日期:2015-01-01 00:00:00
abstract::The optical coherence tomograph is a new, noninvasive technical device that can obtain cross-sectional, high-resolution images-optical coherence tomographs (OCT)-of the retina. This instrument permits an accurate evaluation of various macular and chorioretinal pathologies and the early detection of glaucomatous damage...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820539809056053
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:To evaluate the success rates of endoscopic-assisted probing compared to conventional probing in children 48 months or older. METHODS:This retrospective study included children 48 months and older with CNLDO who underwent endoscopic-assisted probing or conventional probing between January 2011 to August 201...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2017.1284872
更新日期:2018-01-01 00:00:00
abstract::Secondary causes of ocular surface disease are-to a large extent-due to disorders of the ocular adnexae. The main pathomechanisms involved include exposure, abrasion and malnutrition, resulting from a multitude of disorders such as ec- or entropion (e.g. in cicatrizing conjunctivitis), lid retraction and severe aqueou...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820530590931377
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:To present a unique case of a 33-year-old woman using paroxetine who presented with acute unilateral visual loss due to chronic angle-closure glaucoma. METHODS:Case report. RESULTS:A 33-year-old women who had been under paroxetine treatment for the past four months presented at the emergency room due to a sud...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2013.771193
更新日期:2013-07-01 00:00:00
abstract::Retinopathy of prematurity is marked by the proliferative vascularization of the retina in preterm babies. An understanding of the molecular pathogenesis of ROP provides the basis for identifying novel therapeutic targets for treatment. Using the mouse model of oxygen-induced retinopathy, the roles of the hypoxia indu...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820530902800314
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:To evaluate, by ultrasound biomicroscopy (UBM), changes in scleral thickness after ruthenium-106 CCB and CCC plaque (Eckert & Ziegler BE-BIG GmbH, Berlin, Germany) therapy for anterior ciliary melanoma. METHODS:Eleven patients with anterior ciliary melanoma underwent ruthenium-106 CCB and CCC plaque radiation ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2017.1346131
更新日期:2018-01-01 00:00:00
abstract::A 61-year-old female presented with a moderate decrease in vision in the left eye. The patient denied any other ocular or systemic symptoms related to giant cell arteritis. Visual acuity was 20/50 in the left eye with a 2+ relative afferent pupillary defect and markedly abnormal color vision. Dilated fundus examinatio...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820530490882715
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:To investigate changes in retinal and choroidal thickness maps following uncomplicated phacoemulsification using enhanced depth imaging optical coherence tomography (EDI-OCT). METHODS:A prospective study was done on 66 eyes. EDI-OCT was performed preoperative, 1 week, 1 month, and 3 months postoperative meas...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2017.1417453
更新日期:2018-01-01 00:00:00
abstract::A seven-month-old male child was brought in for an eye test for poor vision and nystagmus noticed from four months of age. The child had delayed milestones of development and multiple (six times) episodes of unexplained lower respiratory tract infection (from two months of age) treated by pediatricians at different ce...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2013.835848
更新日期:2015-05-01 00:00:00
abstract::The purpose of this article is to report a case in which a double hemispheric retinal vein occlusion (HSRVO) occurred in the same eye, involving firstly the superior half and later the inferior half of the retina. A 63-year-old woman with ill-controlled hypertension had been diagnosed with central retinal vein occlusi...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820530701420033
更新日期:2007-04-01 00:00:00
abstract::Purpose: The purpose of this study was to investigate the changes of optical coherence tomography angiography (OCTA) parameters in diabetic retinopathy (DR) using an updated software with 3D projection artifact removal. Methods: In this cross-sectional observational study, 192 eyes of 111 patients with diabetes mellit...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2020.1845386
更新日期:2020-08-17 00:00:00
abstract::Age-related macular degeneration (AMD) is a common cause of legal blindness in the developed countries in people older than 50 years of age. AMD complicated by choroidal neovascular membranes (CNV) accounts for 12% of AMD, but for 88% of legal blindness cases. Because of the progressive aging of the population, it is ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820539909056057
更新日期:1999-03-01 00:00:00
abstract::Primary intraocular lymphoma (PIOL) is a type of primary central nervous system lymphoma (PCNSL). It is the most common neoplastic masquerade syndrome involving the eye. Its protean ocular manifestations, plus in many cases the initial positive response to corticosteroid therapy for presumed uveitis, delay accurate di...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820530500350498
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Glaucoma is one of the leading causes of blindness worldwide. Treatment is still largely targeted at lowering intraocular pressure. Intraocular pressures can be lowered through a variety of topical medications, lasers and incisional surgeries. There are currently several classes of topical medications availa...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2020.1818796
更新日期:2020-08-17 00:00:00
abstract::The lacrimal caruncle is a modified cutaneous tissue that contains hair follicles, accessory lacrimal glands, sweat glands, lobules of fat, and sebaceous glands. Due to the nature of tissue, a variety of lesions, both benign and malignant, could arise from this area. Lymphomas of the eye and its adnexa are frequently ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2013.833260
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:The purpose of this study is to evaluate the characteristics and publication outcomes of abstracts presented in American Academy of Ophthalmology (AAO) meetings. SUBJECT AND METHODS:Abstracts from AAO meetings for the years 2012 and 2013 were evaluated from the meeting archives. The study characteristics were ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2019.1581819
更新日期:2019-01-01 00:00:00
abstract::Purpose: To evaluate detailed corneal parameters of inflammatory bowel disease (IBD) patients, including Crohn's disease (CD) and ulcerative colitis (UC) patients, and to assess associations between anterior segment values and other clinical variables.Methods: This prospective cross-sectional case-control study at a t...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2019.1684525
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To describe utilization trends of an ophthalmology-specific emergency department (ED). METHODS:Prospective cohort study of new patients presenting in the ophthalmology ED for at least a 30-day period in the spring of each year for five consecutive years (2010-14) at a university referral center. A data form,...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2016.1188129
更新日期:2018-01-01 00:00:00