Disturbances of the Perioperative Microbiome Across Multiple Body Sites in Patients Undergoing Pancreaticoduodenectomy.

abstract：:In this study, we performed a detailed analysis of the immunoreactive (IR) patterns and tissue distribution of vasoactive intestinal polypeptide (VIP), neuropeptide Y (NPY), and gastrin-releasing peptide (GRP) in the feline pancreas by means of immunohistochemical and radioimmunological techniques. Immunoreactivity fo...

journal_title：Pancreas

authors： De Giorgio R,Sternini C,Brecha NC,Widdison AL,Karanjia ND,Reber HA,Go VL

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate whether 6 candidate serum miRNAs and their interactions with serum folate level were associated with the risk for pancreatic cancer (PC). METHOD:A hospital-based case-control study including 74 incident PC cases and 74 controls was conducted. Serum folate and miRNAs ...

journal_title：Pancreas

authors： Tian Y,Xue Y,Ruan G,Cheng K,Tian J,Qiu Q,Xiao M,Li H,Yang H,Wang L

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:Patients undergoing therapeutic endoscopic retrograde cholangiopancreatography (ERCP) are at a higher risk of developing post-ERCP pancreatitis than patients undergoing diagnostic ERCP. The aim of this study was to evaluate the effectiveness of somatostatin in preventing post-therapeutic ERCP pancreatitis. ...

journal_title：Pancreas

authors： Lee KT,Lee DH,Yoo BM

更新日期：2008-11-01 00:00:00

abstract：:Solitary fibrous tumor (SFT) arising in the pancreas is exceedingly rare, with only 11 cases reported in the English literature. All cases described thus far have exhibited benign histology. We report the first case of malignant SFT of the pancreas. The patient was a 52-year-old woman who presented with obstructive ja...

journal_title：Pancreas

authors： Estrella JS,Wang H,Bhosale PR,Evans HL,Abraham SC

更新日期：2015-08-01 00:00:00

abstract：:Sarcophytol A (SaA), a cembrane-type diterpene isolated from the marine soft coral Sarcophyton glaucum showed anticancer and cancer preventive effects in two different experiments. Growth of transplanted human pancreatic cancer cells (MIA paca-2, 1 x 10(7)) in nude mice (BALB/C 4W female) (Experiment 1) and pancreatic...

journal_title：Pancreas

authors： Yokomatsu H,Satake K,Hiura A,Tsutsumi M,Suganuma M

更新日期：1994-07-01 00:00:00

abstract：:Glucocorticoids are effective in the treatment of certain leukemias and lymphomas, but their effects on the growth of several solid tumors have not been determined. We report here that cortivazol (CVZ), a potent synthetic glucocorticoid, inhibits the growth of a hamster pancreatic adenocarcinoma, H2T, in vivo. CVZ reg...

journal_title：Pancreas

authors： Evers BM,Thompson EB,Townsend CM Jr,Lawrence JL,Johnson B,Srinivasan G,Thompson JC

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:Nuclear factor κB (NF-κB) plays an intrinsic role in promoting growth, angiogenesis, and metastasis in pancreatic cancer (PC) and serves as a mechanism underlying therapeutic resistance. Accordingly, we investigated the efficacy of bioactive phytochemicals in inhibiting radiotherapy (RT)-induced NF-κB activi...

journal_title：Pancreas

authors： Veeraraghavan J,Natarajan M,Lagisetty P,Awasthi V,Herman TS,Aravindan N

更新日期：2011-10-01 00:00:00

abstract：:The influence of pancreatic secretions on growth and brush-border enzyme activity, throughout the entire small intestine, was examined in the rat. Pancreatic secretions were excluded from the gut lumen by stapling the pancreatic ducts, without interruption of bile flow. The entire small intestine was studied as four s...

journal_title：Pancreas

authors： Hauer-Jensen M,Christensen K,Wilson HD,Schedl HP

更新日期：1987-01-01 00:00:00

abstract：:This review discusses the current imaging modalities for the diagnosis and staging of solid and cystic pancreatic lesions and for the assessment of acute and chronic pancreatitis, and the future role of emerging technologies in the management of pancreatic diseases. Multidetector row spiral computed tomography is supe...

journal_title：Pancreas

authors： Nichols MT,Russ PD,Chen YK

更新日期：2006-10-01 00:00:00

abstract：INTRODUCTION:Hypercytokinemia is known to occur in severe acute pancreatitis, suggesting that the production, deposition, and degradation of the extracellular matrix (ECM) occur actively as a result of the actions of the complicated cytokine network. AIMS AND METHODOLOGY:To examine the influence of cytokines and growt...

journal_title：Pancreas

authors： Nakae H,Endo S,Inoue Y,Fujino Y,Wakabayashi G,Inada K,Sato S

更新日期：2003-03-01 00:00:00

abstract：:Genistein is a plant isoflavonoid bearing potent tumor growth-regulating characteristics. This effect of genistein has been attributed partially to its tyrosine kinase-regulating properties, resulting in cell-cycle arrest and limited angiogenesis. Genistein has been used in chemotherapy-resistant cases of advanced leu...

journal_title：Pancreas

authors： Boros LG,Bassilian S,Lim S,Lee WN

更新日期：2001-01-01 00:00:00

abstract：:The Second International Islet Transplantation Symposium was held at UCLA in January, 1993. The symposium, sponsored by the Jerry's Foundation for Diabetes Research was focused on the issues in clinical islet transplantation. The leaders from each of the clinically active programs around the world were invited to disc...

journal_title：Pancreas

authors： Brunicardi FC,Mullen Y

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:To develop a ¹³C-labeled substrate breath test by defining the optimal ¹³C-labeled substrate, substrate dose, test meal, and duration of the test and evaluating its accuracy for the diagnosis of pancreatic exocrine insufficiency (PEI) in chronic pancreatitis (CP). METHODS:Five consecutive prospective compara...

journal_title：Pancreas

authors： Domínguez-Muñoz JE,Nieto L,Vilariño M,Lourido MV,Iglesias-García J

更新日期：2016-02-01 00:00:00

abstract：:The effect on endogenous beta-endorphins of a new synthetic protease inhibitor was studied in acute pancreatitis. Pancreatitis was induced by the injection of autologous bile mixed with trypsin into the main pancreatic duct after ligation of the accessory duct. Plasma beta-endorphin concentrations and cardiovascular f...

journal_title：Pancreas

authors： Satake K,Hiura A,Ha SS,Nishiwaki H,Umeyama K

更新日期：1991-07-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma is characterized by a high rate of activating mutations involving codon 12 of the K-ras protooncogene. As a means of ras-targeted intervention, the effects of enhanced Krev-1 gene expression on the growth and tumorigenicity of the hamster pancreatic adenocarcinoma cell line PC-1 were e...

journal_title：Pancreas

authors： Leach SD,Berger DH,Davidson BS,Curley SA,Tainsky MA

更新日期：1998-05-01 00:00:00

abstract：:The efficacy of medications to treat pancreatic diseases, even when proven effective by experimental studies, are difficult to prove by controlled clinical trials. In the treatment of acute pancreatitis, prophylactic antibiotics, somatostatin, protease inhibitors, and cholecystokinin (CCK)-receptor antagonists are adv...

journal_title：Pancreas

authors： Kitagawa M,Naruse S,Ishiguro H,Hayakawa T

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVES:An impaired host immunity might concur in determining the dismal prognosis of patients with pancreatic cancer (PC). Our aim was to ascertain whether the immunophenotype pattern of blood lymphocytes in PC correlates with tumor stage, grade, or survival. METHODS:We studied 115 patients with PC, 44 with chroni...

journal_title：Pancreas

authors： Fogar P,Sperti C,Basso D,Sanzari MC,Greco E,Davoli C,Navaglia F,Zambon CF,Pasquali C,Venza E,Pedrazzoli S,Plebani M

更新日期：2006-01-01 00:00:00

abstract：:We performed molecular biological studies as well as immunohistochemical analysis of three cases of giant cell carcinoma of the pancreas. Histologically, one case was a pleomorphic giant cell carcinoma consisting of pleomorphic giant/ small cells and spindle cells, one an osteoclast-like giant cell tumor composed of o...

journal_title：Pancreas

authors： Imai Y,Morishita S,Ikeda Y,Toyoda M,Ashizawa T,Yamamoto K,Inoue T,Ishikawa T

更新日期：1999-04-01 00:00:00

abstract：INTRODUCTION:Proinflammatory cytokines play an important role in the development of type 1 diabetes. Lisofylline (LSF) is a novel anti-inflammatory compound that specifically inhibits proinflammatory cytokine production and action. AIM:To investigate the effect of LSF on diabetes prevention. METHODOLOGY:A mouse with ...

journal_title：Pancreas

authors： Yang Z,Chen M,Fialkow LB,Ellett JD,Wu R,Nadler JL

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:All forms of commonly practiced enteral feeding techniques stimulate pancreatic secretion, and only intravenous feeding avoids it. In this study, we explored the possibility of more distal enteral infusions of tube feeds to see whether activation of the ileal brake mechanism can result in enteral feeding with...

journal_title：Pancreas

authors： Kaushik N,Pietraszewski M,Holst JJ,O'Keefe SJ

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:Members of the transient receptor potential (TRP) channels are involved in mediating the electrical excitability and stimulus-secretion coupling in the pancreatic β-cells. The expression and the relative abundance of different TRP channels in the human β-cells are unknown. The objective of this study was to e...

journal_title：Pancreas

authors： Marabita F,Islam MS

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:Endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) is the main diagnostic modality for pancreatic mass lesions. However, cytology is often indeterminate, leading to repeat FNAs and delay in care. Here, we evaluate whether combining routine cytology with fluorescence in situ hybridization (FISH) ...

journal_title：Pancreas

authors： Reicher S,Boyar FZ,Albitar M,Sulcova V,Agersborg S,Nga V,Zhou Y,Li G,Venegas R,French SW,Chung DS,Stabile BE,Eysselein VE,Anguiano A

更新日期：2011-10-01 00:00:00

abstract：:Examining the actions of L-364,718 on rat pancreatic acini, we found that L-364,718 causes persistent inhibition of cholecystokinin (CCK)-8-stimulated enzyme secretion in acini that were first incubated with L-364,718, washed repeatedly, and then reincubated with CCK-8. This inhibition is maximal after as little as 5 ...

journal_title：Pancreas

authors： Bhat ST,Talkad VD,Pollo DA,Gardner JD

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:C-terminal tensin-like gene (CTEN, also known as TNS4) localizes to focal adhesions and is reported to function as an oncogene in colonic, breast, lung, and gastric cancers. Its role in pancreatic cancer is unknown and was thus investigated in this study. METHODS:C-terminal tensinlike gene expression was ev...

journal_title：Pancreas

authors： Al-Ghamdi S,Cachat J,Albasri A,Ahmed M,Jackson D,Zaitoun A,Guppy N,Otto WR,Alison MR,Kindle KB,Ilyas M

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:Pancreatic duct disruption (PDD) after acute pancreatitis can cause pancreatic collections in the early phase and biliary stenosis (BS) or gastric outlet obstruction (GOO) in the late phase. We aimed to document those late complications after moderate or severe acute pancreatitis. METHODS:Between September ...

journal_title：Pancreas

authors： Sugimoto M,Sonntag DP,Flint GS,Boyce CJ,Kirkham JC,Harris TJ,Carr SM,Nelson BD,Bell DA,Barton JG,Traverso LW

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVES:Amylase level in drains (ALD) has been proposed as a predictor for the development of a clinically significant pancreatic fistula (CS-PF) in patients undergoing a major pancreatic surgery. This study aimed to determine if the ALD in patients who developed a CS-PF after pancreatoduodenectomy is higher than th...

journal_title：Pancreas

authors： Ceroni M,Galindo J,Guerra JF,Salinas J,Martínez J,Jarufe N

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to evaluate the severity of patients with acute pancreatitis (AP) on chronic pancreatitis (CP) and compare this to patients with AP without CP. METHODS:The Maryland Health Services database was queried for all adult inpatient discharges with a primary diagnosis of AP from 1...

journal_title：Pancreas

authors： Akshintala VS,Hutfless SM,Yadav D,Khashab MA,Lennon AM,Makary MA,Hirose K,Andersen DK,Kalloo AN,Singh VK

更新日期：2013-11-01 00:00:00

abstract：:The effects of a specific cholecystokinin (CCK) receptor antagonist (L364,718) and a gastrin receptor antagonist (L365,260) on gastrin-releasing peptide-10 (GRP-10)-stimulated pancreatic secretion were investigated in the anesthetized rat. GRP-10 stimulated pancreatic exocrine secretion in a dose-dependent manner. A d...

journal_title：Pancreas

authors： Terashima H,Debas HT,Bunnett NW

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:Scutellaria baicalensis has been a subject of research interest due to its potential multiple therapeutic benefits. This study was to examine the distribution of baicalein, wogonin, oroxylin A and their glucuronide/sulfate-conjugated metabolites in plasma, colon, small intestine, lung, liver, pancreas, kidne...

journal_title：Pancreas

authors： Lu QY,Zhang L,Moro A,Chen MC,Harris DM,Eibl G,Go VL

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:To study the association of binge drinking and the outcomes of severe acute pancreatitis (SAP). METHODS:This retrospective study included 347 patients with first-attack SAP from January 2001 to February 2004. On the basis of the history of binge drinking or not, the patients were divided into the alcohol (n...

journal_title：Pancreas

authors： Deng L,Xue P,Huang L,Yang X,Wan M,Xia Q

更新日期：2010-03-01 00:00:00