Abstract:
:In this work a mathematical programming model for the optimal design of the bioreaction section of biotechnological processes is presented. Equations for the estimation of the equipment cost derived from a recent publication by the US National Renewable Energy Laboratory (NREL) are also summarized. The cost-optimal design of process units and the optimal scheduling of their operation can be obtained using the proposed formulation that has been implemented in software available from the journal web page or the corresponding author. The proposed optimization model can be used to quantify the effects of decisions taken at a lab scale on the industrial scale process economics. It is of paramount important to note that this can be achieved at the early stage of the development of a biotechnological project. Two case studies are presented that demonstrate the usefulness and potential of the proposed methodology.
journal_name
Bioresour Technoljournal_title
Bioresource technologyauthors
Dheskali E,Michailidi K,de Castro AM,Koutinas AA,Kookos IKdoi
10.1016/j.biortech.2016.10.084subject
Has Abstractpub_date
2017-01-01 00:00:00pages
509-514eissn
0960-8524issn
1873-2976pii
S0960-8524(16)31498-5journal_volume
224pub_type
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