Abstract:
OBJECTIVE:To determine whether the appearance of a spiculated mass on a mammogram is associated with luminal A subtype breast cancer and the factors that may influence the presence or absence of the spiculated mass. MATERIALS AND METHODS:Three hundred seventeen (317) patients who underwent image-guided or surgical biopsy between December 2014 and April 2015 were included in the study. Radiologists conducted retrospective assessments of the presence of spiculated masses according to the criteria of Breast Imaging Reporting and Data System. We used combinations of estrogen receptor (ER), progesterone receptor (PR), human epithelial growth factor receptor 2 (HER2), and Ki67 as surrogate markers to identify molecular subtypes of breast cancer. Pearson chi-square test was employed to measure statistical significance of correlations. Furthermore, we built a bi-variate logistic regression model to quantify the relative contribution of the factors that may influence the presence or absence of the spiculated mass. RESULTS:Seventy-one percent (71%) of the spiculated masses were classified as luminal A. Masses classified as luminal A were 10.3 times more likely to be presented as spiculated mass on a mammogram than all other subtypes. Patients with low Ki67 index (< 14%) and HER2 negative were most likely to present with a spiculated mass on their mammograms (p <0.001) than others. The hormone receptor status (ER and PR), pathology grade, overall breast composition, were all associated with the presence of a spiculated mass, but with less weight in contribution than Ki67 and HER2. CONCLUSION:We observed an association between the luminal A subtype of invasive breast cancer and the presence of a spiculated mass on a mammogram. It is hypothesized that lower Ki67 index and HER2 negativity may be the most significant factors in the presence of a spiculated mass.
journal_name
Korean J Radioljournal_title
Korean journal of radiologyauthors
Liu S,Wu XD,Xu WJ,Lin Q,Liu XJ,Li Ydoi
10.3348/kjr.2016.17.6.846subject
Has Abstractpub_date
2016-11-01 00:00:00pages
846-852issue
6eissn
1229-6929issn
2005-8330journal_volume
17pub_type
杂志文章abstract:OBJECTIVE:To evaluate the interobserver agreement, diagnostic value, and associated clinical factors of automated breast ultrasound (ABUS) coronal features in differentiating breast lesions. MATERIALS AND METHODS:This study enrolled 457 pathologically confirmed lesions in 387 female (age, 46.4 ± 10.3 years), including...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2019.0525
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the feasibility of CT fluoroscopy (CTF)-guided percutaneous transhepatic biliary drainage (PTBD) in emergency patients with acute obstructive cholangitis. MATERIALS AND METHODS:The study included 28 patients admitted to the emergency center due to obstructive jaundice and found to require urgent ...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2009.10.2.144
更新日期:2009-03-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
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更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:To investigate gray matter concentration changes in the brains of narcoleptic patients. MATERIALS AND METHODS:Twenty-nine narcoleptic patient with cataplexy and 29 age and sex-matched normal subjects (mean age, 31 years old) underwent volumetric MRIs. The MRIs were spatially normalized to a standard T1 templ...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2009.10.6.552
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate a novel radiofrequency ablation (RFA) application utilizing an adjustable electrode for treatment of benign thyroid nodules. MATERIALS AND METHODS:From April 2011 to December 2018, 21 patients underwent RFA treatment on 21 thyroid nodules, utilizing an 18-gauge inter...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2019.0724
更新日期:2020-03-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2006.7.3.199
更新日期:2006-07-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2002.3.2.105
更新日期:2002-04-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2018.0564
更新日期:2019-04-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2002.3.3.158
更新日期:2002-07-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2011.12.6.686
更新日期:2011-11-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2014.15.1.37
更新日期:2014-01-01 00:00:00
abstract::Papillary tumor of the bile duct is characterized by the presence of an intraductal tumor with a papillary surface comprising innumerable frondlike infoldings of proliferated columnar epithelial cells surrounding slender fibrovascular stalks. There may be multiple tumors along the bile ducts (papillomatosis or papilla...
journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2002.3.1.57
更新日期:2002-01-01 00:00:00
abstract::Imaging features of metastases to the urinary system may closely mimic primary urinary tract tumors, and differential diagnosis by imaging alone may be problematic or even impossible in some cases. The main purpose of this article was to familiarize radiologists with imaging findings of metastasis to the urinary syste...
journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2018.19.4.742
更新日期:2018-07-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2008.9.s.s65
更新日期:2008-07-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2014.15.5.591
更新日期:2014-09-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2014.15.1.173
更新日期:2014-01-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2017.18.2.299
更新日期:2017-03-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2016.17.1.83
更新日期:2016-01-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2004.5.4.287
更新日期:2004-10-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2001.2.4.222
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journal_title:Korean journal of radiology
pub_type: 杂志文章
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更新日期:2000-01-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2007.8.4.295
更新日期:2007-07-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2018.19.1.54
更新日期:2018-01-01 00:00:00
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journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2017.18.2.392
更新日期:2017-03-01 00:00:00
abstract:Objective:To compare the diagnostic performance of electrocardiogram (ECG)-gated thoracic computed tomography angiography (TCTA) without heart rate (HR) control in ischemic stroke patients with coronary CTA (CCTA) in non-stroke patients for detection of significant coronary artery stenosis. Materials and Methods:From ...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2018.19.5.905
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:We wanted to investigate the hemodynamic effect of fenestrated stents on the renal arteries with using a fluid structure interaction method. MATERIALS AND METHODS:Two representative patients who each had abdominal aortic aneurysm that was treated with fenestrated stent grafts were selected for the study. 3D ...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2010.11.1.95
更新日期:2010-01-01 00:00:00
abstract::This paper reports on issues relating to the optimal use of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid magnetic resonance imaging (Gd-EOB-DTPA MR imaging) together with the generation of consensus statements from a working group meeting, which was held in Seoul, Korea (2010). Gd-EOB-DTPA has been show...
journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2011.12.4.403
更新日期:2011-07-01 00:00:00
abstract::The presence of myocardial ischemia is the most important prognostic factor in patients with ischemic heart disease. Fractional flow reserve (FFR) is a gold standard invasive method used to detect the stenosis-specific myocardial ischemia. FFR-guided revascularization strategy is superior to angiography-guided strateg...
journal_title:Korean journal of radiology
pub_type: 杂志文章,评审
doi:10.3348/kjr.2016.17.3.307
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:Many studies have reported pre-processing effects for brain volumetry; however, no study has investigated whether non-parametric non-uniform intensity normalization (N3) correction processing results in reduced system dependency when using an atlas-based method. To address this shortcoming, the present study ...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2012.13.4.391
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To determine the predictive factors for treatment responsiveness in patients with chronic obstructive pulmonary disease (COPD) at 1-year follow-up by performing quantitative analyses of baseline CT scans. MATERIALS AND METHODS:COPD patients (n = 226; 212 men, 14 women) were recruited from the Korean Obstruct...
journal_title:Korean journal of radiology
pub_type: 杂志文章
doi:10.3348/kjr.2018.0204
更新日期:2019-02-01 00:00:00