Enzymic and nonenzymic mono ADP-ribosylation of proteins in skeletal muscle.

abstract：:Using isolated rat hepatocytes we have shown that glutathione (GSH) depletion by glutathione-S-transferase (GST)-catalyzed conjugation with 1-bromoheptane or phorone was accompanied by a significant elevation in ascorbate synthesis. Glycogenolysis was also stimulated without a significant rise in glucose synthesis. Fu...

journal_title：Biochemical and biophysical research communications

authors： Chan TS,Wilson JX,O'Brien PJ

更新日期：2004-04-23 00:00:00

abstract：:SecB, a molecular chaperone in Escherichia coli, binds a subset of precursor proteins that are exported across the plasma membrane via the Sec pathway. Previous studies showed that SecB bound directly to the mature region rather than to the signal sequence of the precursor protein. To determine the binding pattern of ...

journal_title：Biochemical and biophysical research communications

authors： Tang Y,Pan X,Tai PC,Sui SF

更新日期：2010-03-19 00:00:00

abstract：:Porins are trimeric proteins in the outer membranes of Gram-negative bacteria. Several of them, among them matrix porin of Escherichia coli, form symmetrically voltage-gated ion channels in planar bilayers. Trimers exhibit negative resistance at potentials larger than +/- 90mV. Here we show that, after two pores withi...

journal_title：Biochemical and biophysical research communications

authors： Buehler LK,Rosenbusch JP

更新日期：1993-01-29 00:00:00

abstract：:Neurodegenerative diseases are characterized by distinctive neuropathological alterations, including the cerebral accumulation of misfolded protein aggregates, neuroinflammation, synaptic dysfunction, and neuronal loss, along with behavioral impairments. Traumatic brain injury (TBI) is believed to be an important risk...

journal_title：Biochemical and biophysical research communications

authors： Edwards G 3rd,Moreno-Gonzalez I,Soto C

更新日期：2017-02-19 00:00:00

abstract：:HCV and HBV are the major causes of chronic liver diseases worldwide. Patients with both viruse's co-infection tend to develop severer liver diseases and are at high risk of liver-related death. NS5A protein of HCV plays key roles in HCV replication and inhibition of host immune responses. In this study, we described ...

journal_title：Biochemical and biophysical research communications

authors： Pan Y,Wei W,Kang L,Wang Z,Fang J,Zhu Y,Wu J

更新日期：2007-07-20 00:00:00

abstract：:Nuclear migration in Arabidopsis root hairs is bidirectional and relies on actin filaments. However, how actin filaments regulate the bidirectional movement of nuclei remains unclear. Here, we discovered that nuclei migrate forward and backward according to the developmental stage of the hair cells. In addition, the m...

journal_title：Biochemical and biophysical research communications

authors： Zhang S,Liu J,Xue X,Tan K,Wang C,Su H

更新日期：2019-11-19 00:00:00

abstract：:The beta-subunit of human chorionic gonadotropin (beta-hCG) is secreted by many kinds of tumors and it has been used as an ideal target antigen to develop vaccines against tumors. In view of the low immunogenicity of this self-peptide,we designed a method based on isocaudamer technique to repeat tandemly the 10-residu...

journal_title：Biochemical and biophysical research communications

authors： Yankai Z,Rong Y,Yi H,Wentao L,Rongyue C,Ming Y,Taiming L,Jingjing L,Jie W

更新日期：2006-07-14 00:00:00

abstract：:Monoclonal antibody prepared against highly purified rat liver G6PD was used to probe the mode of regulation of this enzyme in a mammalian model system. Material cross-reacting with antibody against liver G6PD was found in similar amounts in extracts of two genetically related rat hepatoma cell lines, only one of whic...

journal_title：Biochemical and biophysical research communications

authors： Dao ML,Johnson BC,DeLuca C

更新日期：1984-02-14 00:00:00

abstract：:Spin-trapping experiments in alkaline aqueous dimethyl sulfoxide (DMSO) solution using sodium 3,5-dibromo-4-nitrosobenzenesulfonate (DBNBS) yielded a strong signal of the sulfur trioxide anion radical adduct. This radical adduct is identical to that obtained by the oxidation of sulfite with horseradish peroxidase/hydr...

journal_title：Biochemical and biophysical research communications

authors： Stolze K,Mason RP

更新日期：1987-03-30 00:00:00

abstract：:The physiological importance of the intestinal plasma membrane calcium pump, isoform 1, (Pmca1, Atp2b1), in calcium absorption and homeostasis has not been previously demonstrated in vivo. Since global germ-line deletion of the Pmca1 in mice is associated with embryonic lethality, we selectively deleted the Pmca1 in i...

journal_title：Biochemical and biophysical research communications

authors： Ryan ZC,Craig TA,Filoteo AG,Westendorf JJ,Cartwright EJ,Neyses L,Strehler EE,Kumar R

更新日期：2015-11-06 00:00:00

abstract：:The synthesis of sufficient amounts of oligosaccharides is the bottleneck for the study of their biological function and their possible use as drug. As an alternative for chemical synthesis, we propose to use Escherichia coli as a "living factory." We have addressed the production of the Galp alpha(1-3)Galp beta(1-4)G...

journal_title：Biochemical and biophysical research communications

authors： Bettler E,Imberty A,Priem B,Chazalet V,Heyraud A,Joziasse DH,Geremia RA

更新日期：2003-03-14 00:00:00

abstract：:The mouse nuclear receptor ERRgamma (estrogen receptor-related receptor gamma) is highly expressed in heart, skeletal muscle, kidney, and brain, as well as in the developing nervous system. We found that the expression of the coactivators PGC-1 (PGC-1alpha) and PERC (PGC-1beta) in mammalian cells augmented potently th...

journal_title：Biochemical and biophysical research communications

authors： Hentschke M,Süsens U,Borgmeyer U

更新日期：2002-12-20 00:00:00

abstract：:Membrane-bound angiotensin-converting enzyme (ACE) expressed in Chinese hamster ovary (CHO) cells is proteolytically released in soluble form into the medium. We find that this release is stimulated up to 50-fold by phorbol-12,13-dibutyrate and also by the addition of fresh, serum-containing media. Concomitant with th...

journal_title：Biochemical and biophysical research communications

authors： Ehlers MR,Scholle RR,Riordan JF

更新日期：1995-01-17 00:00:00

abstract：:Bovine conglutinin is a Ca(2+)-dependent serum lectin specific for N-acetylglucosamine. In the present study, we report the exon-intron organization and the sequence of 5'-regulatory region of the conglutinin gene. The coding region of conglutinin mRNA, which encoded the signal peptide and the sequence of the mature p...

journal_title：Biochemical and biophysical research communications

authors： Kawasaki N,Itoh N,Kawasaki T

更新日期：1994-01-28 00:00:00

abstract：:Methanococcus voltae produces two flagellins of molecular weight 31,000 and 33,000. Amino acid analysis as well as peptide mapping with cyanogen bromide, chymotrypsin and Staphylococcus aureus V-8 protease indicates that the two flagellins are distinct. N-terminal sequencing of the 31,000 Mc. voltae flagellin as well ...

journal_title：Biochemical and biophysical research communications

authors： Kalmokoff ML,Karnauchow TM,Jarrell KF

更新日期：1990-02-28 00:00:00

abstract：:Suppressor of cytokine signaling (SOCS) 1 was initially identified as an intracellular negative feedback regulator of the JAK-STAT signal pathway. Recently, it has been suggested that SOCS1 affects signals of growth factors and hormones. One of them, SOCS1, is also known to be involved in auto-regulation of IRS-1-medi...

journal_title：Biochemical and biophysical research communications

authors： Inaba M,Saito H,Fujimoto M,Sumitani S,Ohkawara T,Tanaka T,Kouhara H,Kasayama S,Kawase I,Kishimoto T,Naka T

更新日期：2005-03-25 00:00:00

abstract：:In the present study the molecular mechanisms underlying tetradecanoylphorbol-13-acetate (TPA) mediated regulation of the human gamma-glutamyltransferase (GGT) gene were examined. TPA challenge of HeLa cells resulted in an increase of GGT mRNA and enzyme activity. Deletion analysis of the promoter revealed that the -3...

journal_title：Biochemical and biophysical research communications

authors： Daubeuf S,Duvoix A,Wellman-Rousseau M,Diederich M,Visvikis A

更新日期：2004-01-09 00:00:00

abstract：:Mouse thymocytes were separated into cortical and medullary subpopulations by differential agglutination with peanut agglutinin. A high-affinity receptor for 1,25-dihydroxyvitamin D3 is present in medullary immunocompetent mouse thymocytes and is absent from cortical immature cells. 1,25-dihydroxyvitamin D3, at physio...

journal_title：Biochemical and biophysical research communications

authors： Ravid A,Koren R,Novogrodsky A,Liberman UA

更新日期：1984-08-30 00:00:00

abstract：:Maximal stimulation of inositol 1,4,5 trisphosphate (IP3) production by epinephrine and carbachol in rat parotid cell aggregates is additive when the two agents are employed simultaneously. The additive response proceeds through both the alpha 1-adrenergic and muscarinic-cholinergic signal transduction pathways. It is...

journal_title：Biochemical and biophysical research communications

authors： Kowatch MA,Roth GS

更新日期：1991-05-15 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been reported as essential regulators in human cancers, including lung adenocarcinoma (LUAD). In the present study, we found that lncRNA long intergenic non-protein coding RNA 467 (LINC00467) was expressed higher in TCGA LUAD samples and predicted poor prognosis in LUAD patients. Hi...

journal_title：Biochemical and biophysical research communications

authors： Yang J,Liu Y,Mai X,Lu S,Jin L,Tai X

更新日期：2019-06-18 00:00:00

abstract：:In this study, we examined the endothelin (ET) receptor subtype involved in mitogenic signaling in human primary and metastatic melanoma cell lines. In a reverse transcriptase-polymerase chain reaction (RT-PCR) study, ET(B) mRNA expression in metastatic melanoma cells was decreased from that of primary melanoma. Only ...

journal_title：Biochemical and biophysical research communications

authors： Kikuchi K,Nakagawa H,Kadono T,Etoh T,Byers HR,Mihm MC,Tamaki K

更新日期：1996-02-27 00:00:00

abstract：:Notch signaling is essential for cell-fate specification in metazoans, and dysregulation of the pathway leads to a variety of human diseases including heart and vascular defects as well as cancer. Glycosylation of the Notch extracellular domain has emerged as an elegant means for regulating Notch activity, especially ...

journal_title：Biochemical and biophysical research communications

authors： Takeuchi H,Haltiwanger RS

更新日期：2014-10-17 00:00:00

abstract：:Growth hormone (GH) regulates many of the factors responsible for controlling the development of bone marrow progenitor cells (BMPCs). The aim of this study was to elucidate the role of GH in osteogenic differentiation of BMPCs using GH receptor null mice (GHRKO). BMPCs from GHRKO and their wild-type (WT) littermates ...

journal_title：Biochemical and biophysical research communications

authors： Cool SM,Grünert M,Jackson R,Li H,Nurcombe V,Waters MJ

更新日期：2005-12-16 00:00:00

abstract：:The growth and metastasis of tumors depend on angiogenesis. Tumor angiogenesis is initiated by the secretion of growth factors from tumor cells; downstream signals are then triggered in pre-existing blood vessels to sprout a new vascular network. Trichosanthin (TCS) is a type I ribosome-inactivating protein that has a...

journal_title：Biochemical and biophysical research communications

authors： He D,Jin J,Zheng Y,Bruce IC,Tam S,Ma X

更新日期：2013-01-11 00:00:00

abstract：:There is increasing evidence that a functional interaction exists between interleukin-1beta (IL-1beta) and N-methyl-D-aspartate (NMDA) receptors. The present study attempted to elucidate the effect of IL-1beta on the NMDA-induced outward currents in mechanically dissociated hippocampal neurons using a perforated patch...

journal_title：Biochemical and biophysical research communications

authors： Zhang R,Yamada J,Hayashi Y,Wu Z,Koyama S,Nakanishi H

更新日期：2008-08-08 00:00:00

abstract：:The carboxyl terminus of the type 1 angiotensin II receptor (AT(1)) plays an important role in receptor phosphorylation, desensitization, and internalization. The yeast two-hybrid system was employed to isolate proteins associated with the carboxyl terminal region of the AT(1A) receptor. In the present study, we repor...

journal_title：Biochemical and biophysical research communications

authors： Guo DF,Chenier I,Tardif V,Orlov SN,Inagami T

更新日期：2003-10-31 00:00:00

abstract：:Human thymidine phosphorylase (dThdPase) is thought to be identical to an angiogenesis factor, platelet-derived endothelial cell growth factor (PD-ECGF). However, the whole amino acid sequence of dThdPase is still unknown. N-terminal amino acid sequencing of dThdPase isolated from human placenta gave the sequence Ac-A...

journal_title：Biochemical and biophysical research communications

authors： Miyadera K,Dohmae N,Takio K,Sumizawa T,Haraguchi M,Furukawa T,Yamada Y,Akiyama S

更新日期：1995-07-26 00:00:00

abstract：:Sorting motifs are involved in the transport of diverse proteins. In the present study, we identified a hydrophobic peptide (WRPWRNFWWSIRVPWRRN) that was able to target enhanced green fluorescent protein- or DsRed2-enriched vesicular-like sub-compartments of the endoplasmic reticulum (ER). Analysis of mutation constru...

journal_title：Biochemical and biophysical research communications

authors： Nie YW,Wang M,Zhang P,Huan L,Liu DJ

更新日期：2016-04-22 00:00:00

abstract：:Abdominal aortic aneurysm (AAA) is relatively common in elderly patients with atherosclerosis. MURC (muscle-restricted coiled-coil protein)/Cavin-4 modulating the caveolae function of muscle cells is expressed in cardiomyocytes, skeletal muscle cells and smooth muscle cells. Here, we show a novel functional role of MU...

journal_title：Biochemical and biophysical research communications

authors： Miyagawa K,Ogata T,Ueyama T,Kasahara T,Nakanishi N,Naito D,Taniguchi T,Hamaoka T,Maruyama N,Nishi M,Kimura T,Yamada H,Aoki H,Matoba S

更新日期：2017-06-03 00:00:00

abstract：:The present study demonstrates that exposure of human thyroid slices to thyrotropin causes an increase in phospholipid metabolism as measured by an increased incorporation of myo-2-[3H]-inositol into phosphatidylinositol, the generation of InsP3 and formation of GInsP as well as metabolism of phosphatidylcholine and p...

journal_title：Biochemical and biophysical research communications

authors： Mosko P,Zarzycki W,Jaroszewicz L,Kinalska I

更新日期：1994-06-30 00:00:00