Amniotic Fluid Embolism.

Abstract:

:Amniotic fluid embolism remains one of the most devastating conditions in obstetric practice with an incidence of approximately 1 in 40,000 deliveries and a reported mortality rate ranging from 20% to 60%. The pathophysiology involves an abnormal maternal response to fetal tissue exposure associated with breaches of the maternal-fetal physiologic barrier during parturition. This response and its subsequent injury involve activation of proinflammatory mediators similar to that seen with the classic systemic inflammatory response syndrome. Maternal treatment is primarily supportive, whereas prompt delivery in the mother who has sustained cardiopulmonary arrest is critical for improved newborn outcome.

authors

Shamshirsaz AA,Clark SL

doi

10.1016/j.ogc.2016.07.001

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

779-790

issue

4

eissn

0889-8545

issn

1558-0474

pii

S0889-8545(16)30031-6

journal_volume

43

pub_type

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