Classical intracranial chondrosarcoma: A case report.

abstract：:The DNA methyltransferase 3A (DNMT3A) -448A>G polymorphism is a novel functional single nucleotide polymorphism (SNP) that contributes to the genetic susceptibility to gastric cancer. In this study, we aimed to assess the genotype frequencies of DNMT3A -448A>G in colorectal cancer (CRC) patients and healthy control su...

journal_title：Oncology letters

authors： Zhao Z,Li C,Song Y,Wu Q,Qiao F,Fan H

更新日期：2012-02-01 00:00:00

abstract：:Hyperparathyroidism is characterized by the oversecretion of parathyroid hormone biochemically and increased cell proliferation histologically. Primary and secondary hyperparathyroidism exhibit distinct pathophysiology but share certain common microscopic features. The present study performed the first genome-wide exp...

journal_title：Oncology letters

authors： Lee F,Lee JJ,Jan WC,Wu CJ,Chen HH,Cheng SP

更新日期：2016-07-01 00:00:00

abstract：:Angiomatoid fibrous histiocytoma (AFH) is a rare, low-grade malignant potential soft tissue tumor which occurs most commonly in children and young adults. Only a few case reports have been described that typically occur in the extremities of the deep dermis and subcutaneous tissue, followed by the trunk, as well as th...

journal_title：Oncology letters

authors： Xiang L,Zhou J,Gu W,Yang B

更新日期：2013-06-01 00:00:00

abstract：:Pancreatic cancer is one of the most frequently occurring malignancies worldwide and it is the fourth most common cause of cancer-associated mortality in Western countries. Thalidomide (THD) plays an important role in tumor therapy, as it is able to promote early stage apoptosis and inhibit the process of angiogenesis...

journal_title：Oncology letters

authors： Qiao Z,Yuan J,Shen J,Wang C,He Z,Hu Y,Zhang M,Xu C

更新日期：2015-05-01 00:00:00

abstract：:The purpose of the present study was to explore the targets of forkhead box D3 (FOXD3) in lung cancer, and thus contribute to the diagnosis and therapy of the disease. The gene expression profile of GSE64513 was downloaded from the Gene Expression Omnibus database. The dataset contained 3 FOXD3 knockout A549 lung canc...

journal_title：Oncology letters

authors： Jiang W,Liu P,Li X

更新日期：2018-03-01 00:00:00

abstract：:Pyruvate kinase isoenzyme M2 (PKM2) has previously been identified as a tumor biomarker and as a potential target for cancer therapy. In this study, F§FJ-5, a characterized naphthoquinone modifier of mollugin, was synthesized in order to investigate its anticancer activity and the potential mechanisms. It was observed...

journal_title：Oncology letters

authors： Wei X,Li M,Ma M,Jia H,Zhang Y,Kang W,Wang T,Shi X

更新日期：2017-02-01 00:00:00

abstract：:MicroRNA (miR)-125a-3p is derived from the 3'-end of pre-miR-125a, which is associated with several types of cancer, such as gastric and prostate cancer, and glioma. The aim of the present study was to identify the prognostic significance of miR-125a-3p expression levels in patients with NSCLC. The gene expression omn...

journal_title：Oncology letters

authors： Hou L,Luo P,Ma Y,Jia C,Yu F,Lv Z,Wu C,Fu D

更新日期：2017-10-01 00:00:00

abstract：:Xeroderma pigmentosum variant (XP-V) is a subtype of xeroderma pigmentosum (XP) disease with typical pigmentation and types of cancer in the oral maxillofacial and other sun-exposed regions. Few factors of tumor proneness in XP-V have been completely elucidated with the exception of the POLH [which encodes DNA polymer...

journal_title：Oncology letters

authors： Guo J,Zhou G,Zhang W,Song Y,Bian Z

更新日期：2013-12-01 00:00:00

abstract：:Solitary fibrous tumors (SFTs) are uncommon, with the pleura as a site of predilection. Central nervous system SFTs, particularly intracranial SFTs, are extremely rare. The lesions are generally benign and localized, and surgery is the main therapeutic solution. The current study reports the cases of a patient who pre...

journal_title：Oncology letters

authors： Wang ZY,Qiu K,Ma YH,Wang XT,Bao JJ,Zhang ZF,Liu XZ

更新日期：2016-02-01 00:00:00

abstract：:The present study aimed to explore the expression of microRNA (miRNA or miR) in drug-resistant and drug-sensitive ovarian cancer cell lines, and to seek the potential therapeutic target of ovarian cancer drug-resistant mechanism in order to improve drug resistance by altering miRNA levels. The drug-resistant character...

journal_title：Oncology letters

authors： Liu J,Wu X,Liu H,Liang Y,Gao X,Cai Z,Wang W,Zhang H

更新日期：2016-09-01 00:00:00

abstract：:The upregulation of EPH receptor B4 (EPHB4) results in a survival advantage for tumor cells via the inhibition of the casapse-8-mediated apoptotic pathway, which begins from the cell membrane. The present study investigated the expression patterns of EPHB4, ephrin B2 (EFNB2) and caspase-8 in patients with esophageal s...

journal_title：Oncology letters

authors： Ni Q,Chen P,Zhu B,Li J,Xie D,Ma X

更新日期：2020-01-01 00:00:00

abstract：:The expression level and roles of microRNA-497 (miR-497) have been frequently reported in previous studies on cancer. However, its expression, function and associated molecular mechanisms in retinoblastoma remain unknown. In the present study, miR-497 expression levels in human retinoblastoma tissues, normal retinal t...

journal_title：Oncology letters

authors： Li J,Zhang Y,Wang X,Zhao R

更新日期：2017-06-01 00:00:00

abstract：:Human four-and-a-half LIM domains protein 1 (FHL1) is a member of the FHL protein family, which serves an important role in multiple cellular events by interacting with transcription factors using its cysteine-rich zinc finger motifs. A previous study indicated that FHL1 was downregulated in several types of human can...

journal_title：Oncology letters

authors： Li SZ,Hu YY,Zhao JL,Zang J,Fei Z,Han H,Qin HY

更新日期：2020-06-01 00:00:00

abstract：:This study investigated the inhibitory effect of vitamin D-binding protein-derived macrophage-activating factor (GcMAF) on carcinogenesis and tumor growth, using a 9,10-dimethyl-1,2-benzanthracene (DMBA)-induced hamster cheek pouch carcinogenesis model, as well as the cytocidal effect of activated macrophages against ...

journal_title：Oncology letters

authors： Toyohara Y,Hashitani S,Kishimoto H,Noguchi K,Yamamoto N,Urade M

更新日期：2011-07-01 00:00:00

abstract：:This study investigated the mRNA levels of thymidylate synthetase (TYMS) and dihydropyrimidine dehydrogenase (DPYD) in esophageal squamous cell carcinoma (ESCC). TYMS and DPYD gene expression was quantified using real-time RT-PCR in 56 patients with ESCC, co-amplified with glyceraldehyde-3-phosphate dehydrogenase as a...

journal_title：Oncology letters

authors： Kimura M,Kuwabara Y,Mitsui A,Ishiguro H,Sugito N,Tanaka T,Shiozaki M,Naganawa Y,Takeyama H

更新日期：2011-03-01 00:00:00

abstract：:The aim of the present study was to obtain comprehensive microRNA (miRNA) profiles of type I [Ishikawa (ISK)] and type II (HEC-1B) human endometrial adenocarcinoma cell lines, utilizing the latest high-throughput sequencing techniques. RNA was extracted from ISK and HEC-1B cell lines. Sequencing results were obtained ...

journal_title：Oncology letters

authors： Lu J,Zhang X,Zhang R,Ge Q

更新日期：2015-12-01 00:00:00

abstract：:Although hepatocellular carcinoma (HCC) is associated with poor prognosis worldwide, the molecular mechanisms underlying the carcinogenesis and progression of this disease remain unclear. Several tumor characteristics have previously been demonstrated to be prognostic factors of survival following hepatic resection, o...

journal_title：Oncology letters

authors： Inokawa Y,Inaoka K,Sonohara F,Hayashi M,Kanda M,Nomoto S

更新日期：2016-11-01 00:00:00

abstract：:Metastasis negatively affects the prognosis of hepatocellular carcinoma (HCC). In the present study, niclosamide, which is known to suppress the proliferation of HCC cells, was investigated for possible suppressant effects on the migration of HCC cells. HLF and PLC/PRF/5 HCC cells were cultured in the presence of nicl...

journal_title：Oncology letters

authors： Tomizawa M,Shinozaki F,Motoyoshi Y,Sugiyama T,Yamamoto S,Ishige N

更新日期：2015-12-01 00:00:00

abstract：:Liver cancer, particularly hepatocellular carcinoma (HCC), is one of leading causes of cancer-related mortality worldwide. Upregulation of the evolutionary conserved Hippo signaling pathway has been observed in HCC patients, and Yes-associated protein 1 (YAP1) has been reported to play a key role in HCC tumorigenesis....

journal_title：Oncology letters

authors： Ruan T,He X,Yu J,Hang Z

更新日期：2016-04-01 00:00:00

abstract：:Taxol is the first-line chemotherapeutic agent for patients with castration-resistant prostate cancer. However, the mechanism of the sensitivity of prostate cancer cells to Taxol treatment remains to be elucidated. In the present study, it was found that paclitaxel induced more apoptosis and maspin expression in phosp...

journal_title：Oncology letters

authors： Gan Y,Chen Q,Lei Y

更新日期：2017-10-01 00:00:00

abstract：:In order to estimate the effects of small interfering RNA (siRNA) targeting retinoblastoma binding protein 2 (RBP2) on the proliferation, expression, invasion, migration and tumorigenicity abilities of papillary thyroid carcinoma K1 cells, siRNA targeting RBP2 (RBP2-siRNA) and negative control siRNA were transfected i...

journal_title：Oncology letters

authors： Kong LL,Man DM,Wang T,Zhang GA,Cui W

更新日期：2015-12-01 00:00:00

abstract：:When assessing outcome in hepatocellular carcinoma (HCC), it is important to consider prognostic factors in background non-tumorous liver tissue as well as in the tumor, since multiple occurrence is associated with background liver status such as hepatitis. The current study aimed to elucidate molecular prognostic pre...

journal_title：Oncology letters

authors： Sonohara F,Inokawa Y,Hishida M,Kanda M,Nishikawa Y,Yamada S,Fujii T,Sugimoto H,Kodera Y,Nomoto S

更新日期：2016-12-01 00:00:00

abstract：:The current study reports the case of a large retroperitoneal tumor treated with modified simultaneous integrated boost (SIB) radiotherapy. A 45-year-old female presented to the emergency department complaining of left abdominal pain and fever. A computed tomography scan detected a retroperitoneal tumor of 12×16×16 cm...

journal_title：Oncology letters

authors： Nomiya T,Akamatsu H,Harada M,Ota I,Hagiwara Y,Ichikawa M,Miwa M,Mizutani M,Kato T,Nagaoka A,Tomita Y,Nemoto K

更新日期：2015-06-01 00:00:00

abstract：:Dysregulated expression of long non-coding RNAs has been determined to be important in cancer development; however, their role in tongue squamous cell carcinoma (TSCC) progression and carcinogenesis, to the best of our knowledge, is yet to be elucidated. The present study revealed that long intergenic non-coding RNA 0...

journal_title：Oncology letters

authors： Li X,Rui B,Cao Y,Gong X,Li H

更新日期：2020-03-01 00:00:00

abstract：:The incidence rate of tonsillar cancer is increasing worldwide. The current study identifies a parallel increase in the incidence of tonsillar cancer, human papilloma virus (HPV) and p16 expression among a population from northern Sweden, a sparsely populated area, confirming the strong association between p16 and HPV...

journal_title：Oncology letters

authors： Loizou C,Laurell G,Lindquist D,Öfverman C,Stefansson K,Nylander K,Olofsson K

更新日期：2015-12-01 00:00:00

abstract：:In the present study, the incidence of surgical wound complications in patients with large and deep high-grade soft tissue sarcoma (STS) was investigated. In addition, the disease-specific and event-free survival rates were examined in these patients. In total, 30 adult patients with primary high-grade deep STS with a...

journal_title：Oncology letters

authors： Nakamura T,Matsumine A,Matsubara T,Asanuma K,Uchida A,Sudo A

更新日期：2015-08-01 00:00:00

abstract：:Wiskott-Aldrich syndrome protein family member 3 (WASF3) is required for invasion and metastasis in different cancer cell types, and has been demonstrated to possess prognostic value in various types of human cancer. However, to the best of our knowledge, the expression profile of WASF3 and its correlations with the c...

journal_title：Oncology letters

authors： Wu J,Wang GC,Chen XJ,Xue ZR

更新日期：2014-09-01 00:00:00

abstract：:Recent studies have shown that a small subpopulation of stem-like cancer cells within most solid tumors are responsible for the malignancy of aggressive cancer cells, including tumorigenicity and relapse of solid tumors. These tumor cells may be enriched and maintained in vitro in the presence of growth factors (GFs),...

journal_title：Oncology letters

authors： Kim J,Jung J,Lee SJ,Lee JS,Park MJ

更新日期：2012-03-01 00:00:00

abstract：:Over the latest decade, the role of microRNAs (miRNAs/miRs) has received more attention. miRNAs are small non-coding RNAs that may serve a role as oncogenes or tumor suppressor genes. Certain miRNAs regulate the apoptosis pathway by influencing pro- or anti-apoptotic genes. We hypothesized that increases in the expres...

journal_title：Oncology letters

authors： Ostadrahimi S,Fayaz S,Parvizhamidi M,Abedi-Valugerdi M,Hassan M,Kadivar M,Teimoori-Toolabi L,Asgari M,Shahrokh H,Abolhasani M,Mahdian R,Fard-Esfahani P

更新日期：2018-05-01 00:00:00

abstract：:Ovarian cancer is the most fatal gynecological cancer, with a 5-year survival rate of only 30%. Lysophosphatidic acid (LPA), which possesses growth factor-like functions, is a major regulatory factor in the peritoneal metastasis of ovarian cancer. LPA stimulates the expression of numerous genes that are associated wit...

journal_title：Oncology letters

authors： Wang H,Liu W,Wei D,Hu K,Wu X,Yao Y

更新日期：2014-05-01 00:00:00