Abstract:
:Interleukin-9 is a cytokine classically related to type 2 immune responses whose cellular identity has been recently reevaluated to identify a new specialized T helper subset called Th9 and an innate source referred as innate lymphoid cell type 2. Over the past years, IL-9 has been associated with allergic responses, tumor immunology, and autoimmunity; however, in this review, we will specifically focus on the role of IL-9 and Th9 cells in the context of parasitic infections. We will summarize and discuss all the evidence relating IL-9 expression and function in parasitic infections with a particular emphasis in helminth infections, an important health issue in developing countries; we will also provide a general description and classification of parasites, the immune response and cellular compartments activated in this context, and its implications and future directions towards a complete understanding of this interesting new T helper subset and its potential therapeutic use.
journal_name
Semin Immunopatholjournal_title
Seminars in immunopathologyauthors
Licona-Limón P,Arias-Rojas A,Olguín-Martínez Edoi
10.1007/s00281-016-0606-9subject
Has Abstractpub_date
2017-01-01 00:00:00pages
29-38issue
1eissn
1863-2297issn
1863-2300pii
10.1007/s00281-016-0606-9journal_volume
39pub_type
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journal_title:Seminars in immunopathology
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journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
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journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
doi:10.1007/s00281-007-0071-6
更新日期:2007-06-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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更新日期:2020-04-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1007/s00281-015-0541-1
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journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
doi:10.1007/s00281-017-0658-5
更新日期:2018-02-01 00:00:00
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journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
doi:10.1007/s00281-012-0334-8
更新日期:2012-09-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2010-12-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Seminars in immunopathology
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journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
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更新日期:2015-07-01 00:00:00
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journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
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更新日期:2011-07-01 00:00:00
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journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
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更新日期:2015-01-01 00:00:00