Abstract：
:Naphthenic acids (NAs), a class of structurally diverse carboxylic acids with often complex ring structures and large aliphatic tail groups, are important by-products of many petrochemical processes including the oil sands mining activity of Northern Alberta. While it is evident that NAs have both acute and chronic harmful effects on many organisms, many aspects of their toxicity remain to be clarified. Particularly, while substantive data sets have been collected on NA toxicity in aquatic prokaryote and vertebrate model systems, to date, nothing is known about the toxic effects of these compounds on the embryonic development of aquatic invertebrate taxa, including freshwater mollusks. This study examines under laboratory conditions the toxicity of NAs extracted from oil sands process water (OSPW) and the low-molecular weight model NAs cyclohexylsuccinic acid (CHSA), cyclohexanebutyric acid (CHBA), and 4-tert-butylcyclohexane carboxylic acid (4-TBCA) on embryonic development of the snail Lymnaea stagnalis, a common freshwater gastropod with a broad Palearctic distribution. Evidence is provided for concentration-dependent teratogenic effects of both OSPW-derived and model NAs with remarkably similar nominal threshold concentrations between 15 and 20 mg/L and 28d EC50 of 31 mg/L. In addition, the data provide evidence for substantial toxicokinetic differences between CHSA, CHBA and 4-TBCA. Together, our study introduces Lymnaea stagnalis embryonic development as an effective model to assay NA-toxicity and identifies molecular architecture as a potentially important toxicokinetic parameter in the toxicity of low-molecular weight NA in embryonic development of aquatic gastropods.
journal_name
Chemospherejournal_title
Chemosphereauthors
Johnston CU,Clothier LN,Quesnel DM,Gieg LM,Chua G,Hermann PM,Wildering WCdoi
10.1016/j.chemosphere.2016.11.156subject
Has Abstractpub_date
2017-02-01 00:00:00pages
1578-1588eissn
0045-6535issn
1879-1298pii
S0045-6535(16)31702-7journal_volume
168pub_type
杂志文章相关文献
CHEMOSPHERE文献大全abstract：:In vitro systems make for rapid identification of xenobiotic effects and can be used to study cellular and subcellular toxicity mechanisms. In this report the metabolic competence of two human-derived cell lines, a hepatic (Hep G2) and a pulmonary one (A549) was tested. In the two cell systems the capability to activa...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(98)00321-x
更新日期：1998-12-01 00:00:00
abstract：:In this work we present an assessment of mercury (Hg) and methyl mercury (MeHg) bioaccumulation in different species of marine sponges collected off the Northwestern Mediterranean and Northeastern Atlantic coasts. Overall the results showed significant accumulation of Hg in sponges, with the Mediterranean sponge Chond...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.127515
更新日期：2020-12-01 00:00:00
abstract：:MSWI(Municipal solid waste incineration) fly ash as hazardous wastes usually is treated properly with OPC(ordinary Portland cement) based binders prior to being disposed in security landfill, but some toxic elements present poor stability in its highly alkaline environment. This study developed a novel solidification/...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.126269
更新日期：2020-07-01 00:00:00
abstract：:The acute and chronic toxicity of nine antibiotics used both therapeutically and as growth promoters in intensive farming was investigated on the freshwater crustacean Daphnia magna. The effect of the antibiotics metronidazole (M), olaquindox (OL), oxolinic acid (OA), oxytetracycline (OTC), streptomycin (ST), sulfadia...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(99)00443-9
更新日期：2000-04-01 00:00:00
abstract：:Forty sediments were analyzed for chlorobenzenes (CBs) and hexachlorobutadiene (HCBD) to investigate their pollution topography along the Kaohsiung coast, Taiwan. Maximum CB concentrations found, varied from 15.4ng/gdw for 1,2,3-TCB to 56.8ng/gdw for 1,2,4-TCB, while higher HCBD concentrations were detected among nort...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2004.11.095
更新日期：2005-03-01 00:00:00
abstract：:The presence of iron(III) has long been recognized as a difficulty when ultraviolet absorbance measurements of dissolved organic matter are desired. This interference was studied in water samples of diverse origins and properties, and a procedure is discussed which uses hydroxylamine to reduce up to 10 mg L(-1) (0.18 ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2009.12.062
更新日期：2010-03-01 00:00:00
abstract：:In this study, axenic cultures of sulfate-reducing (SRB) and nitrate-reducing (NRB) bacteria were examined for their ability to methylate inorganic tin and to methylate or dealkylate butyltin compounds. Environmentally relevant concentrations of natural abundance tributyltin (TBT) and 116Sn-enriched inorganic tin were...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.06.030
更新日期：2018-10-01 00:00:00
abstract：:This work was carried out to evaluate the arsenic (As) levels in milk samples of different milch animals, sheep, goats, cows, buffaloes and camels in Tharparkar, Pakistan. The concentration of As in the milk samples of cows, buffalos, sheep, goats and camels were observed in the range of 15.1-18.4, 2.6-7.7, 25.7-33.2,...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2016.09.015
更新日期：2016-12-01 00:00:00
abstract：:We investigated the precipitation of carbonates by Nesterenkonia halobia in a liquid medium at different concentrations of salts and incubation times. N. halobia only produced crystals at salt concentrations of 2.5%, 7.5% and 15%. At 20% salt concentration no crystal formation was observed. Calcite, aragonite and dolo...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(99)00496-8
更新日期：2000-08-01 00:00:00
abstract：:The degradation mechanism of diethyl phthalate (DEP) in natural seawater under UV irradiation was investigated using a combination of intermediates detection and determination of stable carbon isotopic fractionation. Typical intermediates identified with gas chromatography-mass spectrometry (GC-MS) were mono-ethyl pht...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2012.06.045
更新日期：2013-01-01 00:00:00
abstract：:Nano-scale zero-valent iron (nZVI) has been conceived for cost-efficient degradation of chlorinated pollutants in soil as an alternative to e.g permeable reactive barriers or excavation. Little is however known about its efficiency in degradation of the ubiquitous environmental pollutant DDT and its secondary effects ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2015.10.122
更新日期：2016-02-01 00:00:00
abstract：:Toxic sodium cyanate is always present in cyanide-contaminated waste. A new technology for the efficient decomposition of toxic sodium cyanate by hematite was first proposed in this study. The decomposition of sodium cyanate under various atmospheres has been studied. Studies show that sodium cyanate decomposes above ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.127047
更新日期：2020-10-01 00:00:00
abstract：:Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) have recently received attention due to their widespread contamination of the environment. PFOS and PFOA are stable in the environment and resistant to metabolism, hydrolysis, photolysis and biodegradation. PFOS and PFOA have been found in human blood ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2013.06.047
更新日期：2013-09-01 00:00:00
abstract：:In the present study, two fresh water fishes namely, Channa punctatus and Clarias batrachus, were exposed to three sub-acute concentrations of synthetic pyrethroid, cypermethrin, for 96 h to evaluate the role of amino acids in fulfilling the immediate energy needs of fishes under pyrethroid induced stress as well as t...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2010.12.062
更新日期：2011-04-01 00:00:00
abstract：:A field survey of metal concentrations and arbuscular mycorrhizal (AM) components of plants growing on five mining sites was conducted in Chenzhou City, Hunan Province, Southern China and a control site in Hong Kong. Significant differences were observed in the average concentrations of total heavy metals (Pb, Zn, Cu,...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2006.06.037
更新日期：2007-01-01 00:00:00
abstract：:The use of water injection dredging (WID) is increasing in the UK's inland waterways and marinas. Jets of water are injected under low pressure directly into bottom sediment creating a turbulent water-sediment mixture that flows under the influence of gravity. Many of these sediments are highly contaminated and little...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2005.08.009
更新日期：2006-04-01 00:00:00
abstract：:A new analytical method using accelerated solvent extraction was developed for the determination of 10 particle-associated polar and semipolar pesticides. In addition, six deuterated analogues of the target compounds were evaluated as internal standards. The method yielded acceptable accuracy (73-103% recovery) and pr...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2007.09.058
更新日期：2008-02-01 00:00:00
abstract：:The results are presented of a survey planned to assess the presence of high concern chemicals in sediments collected in a northern sector of the Adriatic sea neighboring the Venice lagoon. For the assessment, persistent marker chemicals were selected from the families of polycyclic aromatic hydrocarbons, polychlorobi...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2007.03.020
更新日期：2007-08-01 00:00:00
abstract：:Investigation on the degradability of tetrachloroethene was performed using fresh and mechanically-biologically pretreated household waste. The corresponding metabolites were determined and the experimental conditions were characterized by the concentrations of methane, organic acids, sulfate and nitrate as well as by...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(99)00126-5
更新日期：1999-08-01 00:00:00
abstract：:In this study, computational and statistical models were applied to optimize the inherent parameters of an electrochemical decontamination of synozol red. The effect of various experimental variables such as current density, initial pH and concentration of electrolyte on degradation were assessed at Ti/RuO0·3TiO0·7O2 ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.126673
更新日期：2020-08-01 00:00:00
abstract：:The partition kinetics of chlorobenzenes (CBs) in a sediment-water system were studied to provide a basis for understanding the compounds' behaviour in the natural aquatic environment. A series of chlorobenzenes (CBs) 1,4-dichlorobenzene (DCB), 1,3,5-trichlorobenzene (TCB), 1,2,4,5-tetrachlorobenzene (TeCB), pentachlo...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.08.060
更新日期：2017-11-01 00:00:00
abstract：:At present, sustainable water supply and energy generation are the most important challenges faced by humankind globally. Thus, it is crucial to progress ecological techniques for sustainable removal of organic pollutants from wastewater and generation of hydrogen as an alternative to fossil fuels. In this study, zinc...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.129346
更新日期：2020-12-16 00:00:00
abstract：:Ozonation as final wastewater (WW) polishing step, following conventional activated sludge treatment is increasingly implemented in sewage treatment for contaminant degradation to prevent surface water pollution. While the oxidative degradation of chemicals has been extensively investigated, the in vivo toxicological ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2012.04.017
更新日期：2012-08-01 00:00:00
abstract：:The main operating variables affecting ozonation efficiencies of wastewater from beet molasses alcoholic fermentation have been studied. Semibatch experiments have been performed in order to analyze the influence of pH, bicarbonate ion, temperature and stirring rate on color and organic matter removals. The efficienci...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2005.01.090
更新日期：2005-09-01 00:00:00
abstract：:Fish samples purchased from Japanese markets were analyzed for Dechlorane Plus (DP)(syn-, anti-), polybrominated diphenyl ether (PBDE), and hexabromocyclododecane (HBCD)(α, γ). Twenty fish were analyzed using gas chromatography-mass spectrometry for DP and PBDE, and using liquid chromatography-tandem mass spectrometry...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2012.05.072
更新日期：2012-10-01 00:00:00
abstract：:The aim of this study was to determine a new spectrum of substances that will be selected for future breast milk monitoring in Bavaria, Germany. Up to now, the analysis of breast milk in Bavaria was limited to selected organochlorine pesticides (OCP) and polychlorinated biphenyls (PCB). Information on background level...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2008.01.053
更新日期：2008-05-01 00:00:00
abstract：:The spatial distribution of polyfluoroalkyl compounds (PFCs) and their composition profile was investigated in 48 water samples collected from the German Bight. All samples were prepared by solid-phase extraction with Strata XAW cartridges and analysed using high performance liquid chromatography/negative electrospray...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2009.03.052
更新日期：2009-06-01 00:00:00
abstract：:The behavioral and biochemical responses of Japanese medaka (Oryzias latipes) to acute and subacute (sublethal) levels of chlorpyrifos were studied. In the acute exposure test, medaka were exposed to 0.018, 0.055, 0.166, or 0.500 mg L(-1) chlorpyrifos for 4 d. As a result, fish showed hypoactivity compared to the cont...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2013.02.042
更新日期：2013-06-01 00:00:00
abstract：:The poor mobility of organic pollutants in contaminated sites frequently results in slow remediation processes. Organics, especially hydrophobic compounds, are generally retained strongly in soil matrix as a result of sorption, sequestration, or even formation into non-aqueous-phase liquids and their mobility is thus ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2004.11.043
更新日期：2005-06-01 00:00:00
abstract：:Geochemical investigation was carried out for delineating factors responsible for the mobilization of arsenic (As) from aquifer material into the groundwater. Four sites along Ravi River, (Samada, Sarai Chimba, Kot Maiga and Chah Fatehwala), were selected based on the blanket survey. Groundwater-rock interaction and e...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.02.154
更新日期：2018-06-01 00:00:00
