Real-time Intraoperative Fluorescent Lymphography: A New Technique for Lymphatic Sparing Surgery.

Abstract:

BACKGROUND:Many surgical procedures can produce persistent lymphorrhea, lymphoceles, and lymphedema after lymph node and lymph vessel damage. Appropriate visualization of the lymphatic system is challenging. Indocyanine green (ICG) is a well-known nontoxic dye for lymphatic flow evaluation. ICG fluorescence-guided lymphography has emerged as a promising technique for intraoperative lymphatic mapping. OBJECTIVE:Our goal was to develop a high spatial resolution, real-time intraoperative imaging technique to avoid or recognize early deep lymphatic vessel damage. METHODS:We intraoperatively performed ICG fluorescence-guided lymphography during a kidney transplant. ICG was injected in the subcutaneous tissue of the patient's groin in the Scarpa's triangle. A dedicated laparoscopic high-definition camera system was used. RESULTS:Soon after ICG injection, the lymphatic vessels were identified in the abdominal retroperitoneal compartment as fluorescent linear structures running side by side to the iliac vessels. Surgical dissection was therefore performed, avoiding iatrogenic damage to major lymphatic structures. Another ICG injection at the end of the procedure confirmed that the lymphatic vessels were intact without lymph spread. CONCLUSIONS:Intraoperative lymphatic mapping with an ICG fluorescence-sensitive camera system is a safe and feasible procedure. ICG real-time fluorescence lymphography can be used to avoid or recognize early deep lymphatic vessel damage and reduce postoperative complications related to the lymphatic system.

journal_name

Transplant Proc

authors

Ietto G,Amico F,Soldini G,Chiappa C,Franchin M,Iovino D,Romanzi A,Saredi G,Cassinotti E,Boni L,Tozzi M,Carcano G

doi

10.1016/j.transproceed.2016.08.017

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

3073-3078

issue

9

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(16)30457-2

journal_volume

48

pub_type

杂志文章
  • Ischemic preconditioning improves rat kidney graft function after severe ischemia/reperfusion injury.

    abstract:UNLABELLED:Ischemic preconditioning (IP) has been shown to ameliorate renal ischemia reperfusion injury. Using a rat kidney transplantation model we determined if IP improves graft function after prolonged cold storage. MATERIALS AND METHODS:Syngeneic rat kidneys were divided into two groups. Prior to 42 hours of cold...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2004.12.274

    authors: Fuller TF,Freise CE,Feng S,Niemann CU

    更新日期:2005-01-01 00:00:00

  • BK virus nephropathy in renal transplant recipients in Kuwait: a preliminary report.

    abstract:INTRODUCTION:BK virus nephropathy (BKVN) is a significant cause of graft loss among renal transplant recipients. The treatment outcomes of BKVN have been variably reported in the literature. PATIENTS AND METHODS:We prospectively investigated BKV infection and BKVN among a population of renal transplant recipients with...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2005.08.018

    authors: Nampoory MR,Johny KV,Pacsa A,Nair PM,Said T,Halim MA,Francis I,Samhan M,Mousawi M,Dalawi A,Szucs G,Al-Nakib W

    更新日期:2005-09-01 00:00:00

  • Pulmonary hypertension is closely related to arterial stiffness in renal transplant patients.

    abstract:INTRODUCTION AND AIMS:Pulmonary hypertension (PH) is an independent predictor of increased mortality in patients on dialysis and those undergoing renal transplantation. We investigated PH and its association with vascular calcification and endothelial dysfunction in renal transplant patients. METHODS:The records of 30...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2014.10.070

    authors: Bal Z,Sezer S,Uyar ME,Bal U,Kulah E,Guliyev O,Tutal E,Haberal M

    更新日期:2015-05-01 00:00:00

  • The impact of obesity as determined by modified body mass index on long-term outcome after liver transplantation: Canadian single-center experience.

    abstract:BACKGROUND:Obesity is thought to be associated with higher rates of morbidity and mortality after liver transplantation (LT); however, its actual impact is difficult to evaluate, in part because of the confounding effects of fluid accumulation on body mass index (BMI). OBJECTIVE:We sought to define the effects of conv...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2012.11.009

    authors: Tanaka T,Renner EL,Selzner N,Therapondos G,Lilly LB

    更新日期:2013-07-01 00:00:00

  • Risk factors for the development of new-onset diabetes mellitus in a living related renal transplant program.

    abstract::New-onset diabetes mellitus is associated with considerable morbidity after transplantation. We evaluated 78 living related renal transplant recipients due to all causes except diabetic nephropathy a waiting a living related renal transplantation. We evaluated demographic characteristics, pretransplant glycemic profil...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2010.10.008

    authors: Bora GS,Guleria S,Reddy VS,Tandon N,Gupta N,Gupta S,Bhowmik D

    更新日期:2010-12-01 00:00:00

  • Backtransplantation for survival of the graft.

    abstract::To assess survival of grafts after uncontrollable rejection, one performs backtransplantation from the recipient to the donor. This study investigated backtransplantation in an animal model. Hearts were transplanted heterotopically in rats. After a few days, the transplanted heart grafts were harvested from the recipi...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2005.01.009

    authors: Yuzawa K,Fukunaga K,Ohkohchi N

    更新日期:2005-01-01 00:00:00

  • Effect of calcineurin inhibitors on low-density lipoprotein oxidation.

    abstract:INTRODUCTION:Low-density lipoprotein (LDL) oxidation is considered a key factor in the biological processes that trigger and accelerate atherosclerosis. Reported data suggest that tacrolimus improves the lipid profile in renal transplant recipients. OBJECTIVE:The objective of this study was to analyze the effect of co...

    journal_title:Transplantation proceedings

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.transproceed.2005.10.068

    authors: Cofan F,Cofan M,Campos B,Guerra R,Campistol JM,Oppenheimer F

    更新日期:2005-11-01 00:00:00

  • New-Onset Diabetes After Transplantation: Comparison Between a Cyclosporine-Based and a Tacrolimus-Based Immunosuppressive Regimen.

    abstract:INTRODUCTION:New-onset diabetes after transplantation (NODAT) is a complication of renal transplantation (RT) with an adverse effect on graft survival. OBJECTIVES:The purpose of the present study was to compare modifiable or non-modifiable clinical and laboratory parameters as well as the course of patients and transp...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2018.08.037

    authors: Zolota A,Miserlis G,Solonaki F,Tranda A,Antoniadis N,Imvrios G,Fouzas I

    更新日期:2018-12-01 00:00:00

  • Cytotoxic flow cytometric crossmatch in renal transplantation: a single assay to simultaneously detect antibody binding and cytotoxicity.

    abstract:OBJECTIVES:The complement-dependent lymphocytotoxicity crossmatch (CDC-XM) detects cytotoxic parameters of preformed antibodies. The flow cytometric crossmatch (FCXM) is used to detect the binding of recipient antibodies to donor cells. Because these two assays provide different information, both methods are often perf...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2011.11.024

    authors: Thammanichanond D,Athimang W,Paisooksantivatana K,Mongkolsuk T,Ingsathit A,Worawichawong S,Kitpoka P,Jirasiritham S,Kantachuvesiri S

    更新日期:2012-01-01 00:00:00

  • A 16-fold increase in organ donation in a Hispanic population.

    abstract:UNLABELLED:Organ transplantation as a substitute for diseased organs in end-stage organ failure has led to a worldwide increase in this treatment modality, but donation has not kept pace with the demand, despite scientific, social, and government efforts. For many years, Hispanic donation in Puerto Rico was meager and ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2008.03.120

    authors: Saadé M,Morales-Otero L,Davis J,Torres E,González Z,Santiago-Delpín EA

    更新日期:2008-05-01 00:00:00

  • Effects of Left Ventricular Assist Device Support on End-Organ Function in Patients With Heart Failure: Comparison of Pulsatile- and Continuous-Flow Support in a Single-Center Experience.

    abstract:BACKGROUND:Limited data exist about the effects of continuous-flow versus pulsatile-flow left ventricular assist devices (LVADs) on end-organ function. We hypothesized that a pulsatile Polvad MEV (PM) would result in outcomes similar to those of similarly ill patients implanted with a continuous-flow LVAD (Heartware [H...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2016.01.071

    authors: Nadziakiewicz P,Szygula-Jurkiewicz B,Niklewski T,Pacholewicz J,Zakliczynski M,Borkowski J,Hrapkowicz T,Zembala M

    更新日期:2016-06-01 00:00:00

  • Treatment-resistant recurrent membranoproliferative glomerulonephritis in renal allograft responding to rituximab: case report.

    abstract::We report a case of idiopathic membranoproliferative glomerulonephritis (MPGN) recurring 2 years after a living-unrelated kidney transplantation. The disease was refractory to intravenous immunoglobulin and plasmapheresis. Treatment with 2 doses of rituximab resulted in remission of the disease. The disease relapsed 1...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2015.02.003

    authors: Farooqui M,Alsaad K,Aloudah N,Alhamdan H

    更新日期:2015-04-01 00:00:00

  • Split liver transplantation: where? when? how?

    abstract::Donor scarcity is among the greatest concerns in the transplantation community. Dividing a liver graft theoretically offers a double benefit for candidates on the waiting list. Split liver transplantation entails a higher logistic and technical complexity that is extensively compensated, not only with an increase in t...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/j.transproceed.2012.05.002

    authors: Abradelo M,Sanabria R,Caso O,Álvaro E,Moreno E,Jiménez C

    更新日期:2012-07-01 00:00:00

  • Very low-grade proteinuria at 3 months posttransplantation is an earlier marker of graft survival.

    abstract::Proteinuria is an early finding that appears in the first 3 months after transplantation in half of patients. Frequently, it is very low grade (VLP; <0.5 g/24 h). The aim of this study was to analyze the risk factors and prognostic significance of VLP at 3 months posttransplantation, which was maintained for the first...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.06.137

    authors: Sancho Calabuig A,Pallardó Mateu LM,Avila Bernabeu AI,Gavela Martínez E,Beltrán Catalán S,Crespo Albiach JF

    更新日期:2009-07-01 00:00:00

  • Renal biopsy donor group: the influence of glomerulosclerosis on transplant outcomes.

    abstract::The UNOS donor population was examined from 1999 to 2002, and approximately 25% of the over 23,000 donors were biopsied (Bx). There was a significant trend (P < .001) of older donors, cardiovascular accident, and hypertension in the Bx group versus the non-Bx group. The percent GS was directly correlated (P < .001) to...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2004.12.108

    authors: Cicciarelli J,Cho Y,Mateo R,El-Shahawy M,Iwaki Y,Selby R

    更新日期:2005-03-01 00:00:00

  • Factors affecting survival and tumor recurrence in patients transplanted for hepatocellular carcinoma and coexistent hepatitis C virus.

    abstract::A better understanding of tumor factors influencing patient and graft survival and recurrence of hepatocellular carcinoma (HCC) associated with hepatitis C virus (HCV) cirrhosis may be useful to maximize the benefits of liver transplantation (OLT). Sixty-three adults underwent OLT for end-stage liver disease secondary...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2008.09.022

    authors: Briceño J,Ruiz J,Ciria R,Naranjo A,Sánchez-Hidalgo J,Luque A,Rufián S,de la Mata M,López-Cillero P

    更新日期:2008-11-01 00:00:00

  • Safety and efficacy of once-daily modified-release tacrolimus in liver transplant recipients: a multicenter postmarketing surveillance in Japan.

    abstract:INTRODUCTION:Modified-release formulation of tacrolimus (TAC-MR) has been developed with the intent of improving patient adherence and quality of life. A number of studies have indicated that the efficacy and safety of once-daily TAC-MR were comparable with those of the original formulation, twice-daily tacrolimus. How...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.transproceed.2013.11.071

    authors: Uemoto S,Abe R,Horike H,So M

    更新日期:2014-04-01 00:00:00

  • Reactivations of cytomegalovirus, human herpes virus 6, and Epstein-Barr virus differ with respect to risk factors and clinical outcome after hematopoietic stem cell transplantation.

    abstract::One hundred two recipients of hematopoietic stem cell transplants (HSCTs) 45, from siblings and 57 from matched unrelated donors, were followed for cytomegalovirus (CMV), human herpes virus (HHV) 6, and Epstein-Barr Virus (EBV) reactivation by quantitative polymerase chain reaction in the context of immunologic recons...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2010.07.027

    authors: Jaskula E,Dlubek D,Sedzimirska M,Duda D,Tarnowska A,Lange A

    更新日期:2010-10-01 00:00:00

  • Short-term Results of Heartmate 3 Ventricular Assist Device Implantation for End-Stage Heart Failure.

    abstract:OBJECTIVE:To report our initial experience with Heartmate 3 ventricular assist device (HM3) in cases with end-stage heart failure (ESHF). METHODS:Charts of 8 ESHF patients who underwent HM3 implantation in our clinic from January to June 2016 (group 1) and 16 patients who underwent HM2 implantation during 2015 (group ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2017.01.034

    authors: Ozturk P,Ertugay S,Sahutoglu C,Engin C,Nalbantgil S,Yagdi T,Ozbaran M

    更新日期:2017-04-01 00:00:00

  • Bacteriocins from lactic acid bacteria increases tumor necrosis factor-alpha expression in a rat kidney model of chronic rejection.

    abstract::Chronic allograft dysfunction is the primary cause of graft loss after the first posttransplantation year. Bacteriocins are biologically active proteins exhibiting antimicrobial properties against other bacterial species, which are usually closely related to the producer organism. The objective of our study was to det...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2008.06.099

    authors: Zhu LH,Li C,Wu JA,Liang JG,Shi YF

    更新日期:2008-12-01 00:00:00

  • Adherence to Dietary Recommendations in Maintenance Phase Kidney Transplant Patients.

    abstract:OBJECTIVES:Current adherence to dietary recommendations for chronic kidney disease was evaluated in kidney transplant patients in the maintenance phase. METHODS:A total of 268 maintenance phase kidney transplant patients were included in the study. Estimated daily intakes of oral protein and salt were calculated from ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2015.12.129

    authors: Ichimaru N,Nakazawa S,Yamanaka K,Kakuta Y,Abe T,Kaimori JY,Imamura R,Nonomura N,Takahara S

    更新日期:2016-04-01 00:00:00

  • Age, gender, race, and associations with kidney failure following living kidney donation.

    abstract:INTRODUCTION:Our previous reports suggested that African Americans (AA) are more likely to develop end-stage renal disease (ESRD) following kidney donation when compared with white counterparts. We sought information on age, gender, and race of kidney donors to determine which groups were over-represented on the kidney...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2008.03.104

    authors: Gibney EM,Parikh CR,Garg AX

    更新日期:2008-06-01 00:00:00

  • Assessment of glomerular filtration rate in renal transplant patients using serum cystatin C.

    abstract:AIM:Serum cystatin C (SCysC) has been proposed as a better marker of glomerular filtration rate (GFR) than serum creatinine (Scr). However, few data are available in renal transplant patients, especially, during the early postoperative phase. METHODS:Thirty-nine renal transplant patients (22 men/17 women) were recruit...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2006.07.014

    authors: Xu H,Lu Y,Teng D,Wang J,Wang L,Li Y

    更新日期:2006-09-01 00:00:00

  • Study of Immune Tolerance Cases in Adult Living Donor Liver Transplantation.

    abstract:BACKGROUND:Complete immune tolerance is the chief goal in organ transplantation. This study aimed to evaluate patients who successfully withdrew from immunosuppressive (IS) agents after living donor liver transplantation (LDLT). MATERIALS AND METHODS:A retrospective review of all adult LDLT from July 1999 to March 201...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2015.12.093

    authors: Miura K,Kobayashi T,Zhang Z,Soma D,Hirose Y,Ishikawa H,Takizawa K,Nagahashi M,Sakata J,Kameyama H,Minagawa M,Kosugi S,Koyama Y,Wakai T

    更新日期:2016-05-01 00:00:00

  • Diagnosis of renal allograft rejection and acute tubular necrosis by 99mTc-mononuclear leukocyte imaging.

    abstract::One hundred kidney transplant recipients were evaluated on the first and fifth days after transplantation by Tc-99m mononuclear cell scintigraphy. We have developed a quantitative method to diagnose rejection and acute tubular necrosis (ATN) by comparing regions of interest drawn on allograft scintigraphs at different...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2004.11.100

    authors: Lopes de Souza SA,Barbosa da Fonseca LM,Torres Gonçalves R,Salomão Pontes D,Holzer TJ,Proença Martins FP,Gutfilen B

    更新日期:2004-12-01 00:00:00

  • Use of intraperitoneal ePTFE Gore dual-mesh plus in a giant incisional hernia after kidney transplantation: a case report.

    abstract::We evaluated the incidence of and predisposing factors for an incisional hernia after kidney transplantation. Numerous techniques have been used to repair postoperative fascial dehiscences or simple incisional hernias, but no clear treatment exists for giant hernias. Our aim was to obtain (1) a safe procedure to repai...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.02.060

    authors: Lo Monte AI,Damiano G,Maione C,Gioviale MC,Lombardo C,Buscemi G,Romano M

    更新日期:2009-05-01 00:00:00

  • Early hepatic artery thrombosis after liver transplantation: diagnosis and treatment.

    abstract:BACKGROUND:Hepatic artery thrombosis (HAT) occurs in 3% to 9% of all liver transplantations with acute graft failure as a possible sequel. METHODS:Eleven episodes of HAT were identified among 256 orthotropic liver transplantations (whole, LDCT, split) performed on 253 patients between April 1993 and July 2006. HAT was...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2007.02.017

    authors: Nikeghbalian S,Kazemi K,Davari HR,Salahi H,Bahador A,Jalaeian H,Khosravi MB,Ghaffari S,Lahsaee M,Alizadeh M,Rasekhi AR,Nejatollahi SM,Malek-Hosseini SA

    更新日期:2007-05-01 00:00:00

  • Project-based transplant management as a research statistical support.

    abstract::This paper proposes a transplant management method based on project management concepts applied to organ transplantation processes in all phases to provide statistical support for evidence based medicine (EBM) research. The transplant is viewed as a project composed by phases: (1) Initiation starts with the acknowledg...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.01.058

    authors: Letouze P,Teixeira MM

    更新日期:2009-04-01 00:00:00

  • Influence of HLA matching on survival in heart transplantation.

    abstract:BACKGROUND:In renal transplantation, the degree of HLA matching has been reported to be negatively correlated with graft loss, with the number of rejections with complications. This association is less clear in heart transplantation, where there are contradictory studies, although most are consistent with those in rena...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2005.09.145

    authors: Almenar L,Maeso ML,Martínez-Dolz L,Rueda J,Palomar CG,Sáez AO,Vives MA,Tort MD,Pérez MP

    更新日期:2005-11-01 00:00:00

  • Isolation and culture of beta-like cells from porcine Wirsung duct.

    abstract::We sought to develop a protocol to isolate and culture porcine Wirsung duct cells in order to determine their potency to differentiate into insulin-expressing beta-like cells. The porcine Wirsung duct isolated by a surgical microdissection was digested with collagenase P and trypsin to dissociate ductal cells. These e...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章

    doi:10.1016/j.transproceed.2009.02.062

    authors: Gioviale MC,Damiano G,Montalto G,Buscemi G,Romano M,Lo Monte AI

    更新日期:2009-05-01 00:00:00