Abstract：
OBJECTIVE:To develop and validate a computable phenotype algorithm for identifying patient populations with sickle cell disease. METHODS:In this retrospective study we used electronic health record data from the Children's Hospital of Wisconsin to develop a computable phenotype algorithm for sickle cell disease. The algorithm was on the basis of the International Classification of Diseases, Ninth Revision codes, number of visits, and hospital admissions for sickle cell disease. Using Informatics for Integrating Biology and the Bedside queries, the algorithm was refined in an iterative process. The final algorithm was verified using manual medical records review and by comparison with a gold standard set of confirmed sickle cell cases. The algorithm was then validated at Froedtert Hospital, a neighboring health system for adults. RESULTS:From the Children's Hospital of Wisconsin, our computable phenotype algorithm identified patients with confirmed sickle cell disease with a positive predictive value of 99.4% and a sensitivity of 99.4%. Additionally, using data from Froedtert, the computable phenotype algorithm identified patients with confirmed sickle cell disease with a positive predictive value of 95.8% and a sensitivity of 98.3%. CONCLUSIONS:The computable phenotype algorithm developed in this study had a high sensitivity and positive predictive value when identifying patients with sickle cell disease in the electronic health records of the Children's Hospital of Wisconsin and Froedtert, a neighboring health system for adults. Our algorithm allows us to harness data provided by the electronic health record to rapidly and accurately identify patient with sickle cell disease and is a rich resource for future clinical trials.
journal_name
Acad Pediatrjournal_title
Academic pediatricsauthors
Michalik DE,Taylor BW,Panepinto JAdoi
10.1016/j.acap.2016.12.005subject
Has Abstractpub_date
2017-04-01 00:00:00pages
283-287issue
3eissn
1876-2859issn
1876-2867pii
S1876-2859(16)30535-6journal_volume
17pub_type
杂志文章abstract：OBJECTIVE:To compare preventive care quality for children at risk and not at risk for developmental, behavioral, or social delays. METHODS:Using the 2007 National Survey of Children's Health (n = 22,269), we used the Parents' Evaluation of Developmental Status (PEDS) questionnaire to identify children ages 10 months t...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2012.05.003
更新日期：2012-09-01 00:00:00
abstract：OBJECTIVE:Validated questionnaires help community pediatric services to identify emotional and behavioral problems (EBPs). This study assesses the psychometric properties of the self-report version of the Strengths and Difficulties Questionnaire (SDQ) for the identification of EBPs in adolescents (13 to 14years old) an...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2018.12.008
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:To identify the proportion of patients previously diagnosed with apparent life-threatening events (ALTE) who would meet criteria for brief resolved unexplained events (BRUE) and to identify rates of adverse outcomes in subgroups: ALTE not meeting criteria for BRUE, lower-risk BRUE, and higher-risk ALTE. METH...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2019.08.001
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:Being asleep at the time of a residential fire increases fire-related fatality risk. This study tested whether children awaken from slow wave sleep and perform an escape procedure better to a voice smoke alarm that uses their mother's voice compared with a female stranger's voice or a low-frequency tone alarm...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2019.06.016
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND AND PURPOSE:The coming years could be a watershed period for children and health care as the nation implements the most significant federal health care legislation in 50 years: the Accountable Care Act (ACA). A year earlier, the American Recovery and Reinvestment Act (ARRA) set up a framework and road map fo...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2010.10.003
更新日期：2011-05-01 00:00:00
abstract：:Neonatal intensive care unit networks that encompass regions, states, and even entire countries offer the perfect platform for implementing continuous quality improvement initiatives to advance the health care provided to vulnerable neonates. Through cycles of identification and implementation of best available eviden...
journal_title：Academic pediatrics
pub_type： 杂志文章,评审
doi：10.1016/j.acap.2013.04.014
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:Youth involvement in extracurricular activities may help prevent smoking and drinking initiation. However, the relative roles of types of extracurricular activity on these risks are unclear. Therefore, we examined the association between substance use and participation in team sports with a coach, other sport...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2014.02.002
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVE:To determine if use of a health literacy low-inference, self-assessment measure (LISAM), promoted behavior change as measured by increased use of health literacy communication skills (HLCS). METHODS:The LISAM is a tool used by educators to self-assess their performances after giving a lecture. The tool is lo...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2020.02.019
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:Promoting safe firearm storage in pediatric primary care is one way to address youth suicide by firearm. The study objective was to determine the perspectives of primary care physicians (PCPs) and leaders of primary care practices regarding the acceptability and use of screening, counseling, and firearm locks...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2018.11.007
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The role of a hospitalist differs in a community hospital (CH) compared to a university/children's hospital. Residents are required to practice in a variety of relevant clinical settings, but little is known about current trends regarding pediatric resident training in different hospital settin...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2019.10.006
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:The stress associated with adverse childhood experiences (ACEs) has immediate and long-lasting effects. The objectives of this study were to examine 1) how often pediatricians ask patients' families about ACEs, 2) how familiar pediatricians are with the original ACE study, and 3) physician/practice characteri...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2015.08.002
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:The objective of this study is to provide a comprehensive epidemiological profile detailing food allergy (FA) prevalence and related correlates among Medicaid-enrolled children. METHODS:The 2012 Medicaid Analytic eXtract person-level 100% files for 50 states and the District of Columbia were analyzed. The an...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2020.03.005
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVE:To identify factors that influence faculty to promote or reduce the expression of autonomy for pediatric hospital medicine (PHM) fellows and describe behaviors faculty employ to support fellow autonomy in the clinical setting. METHODS:This was a multicenter, qualitative study using semistructured interviews ...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2019.05.003
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:To explore the potential benefits and challenges of involving adolescents in the education of medical students and residents from the perspectives of adolescents who are hospitalized with chronic health conditions. METHODS:We conducted qualitative interviews with adolescents at a Canadian pediatric hospital....
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2018.05.007
更新日期：2019-01-01 00:00:00
abstract：:This paper provides a primer for qualitative research in medical education. Our aim is to equip readers with a basic understanding of qualitative research and prepare them to judge the goodness of fit between qualitative research and their own research questions. We provide an overview of the reasons for choosing a qu...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2011.05.001
更新日期：2011-09-01 00:00:00
abstract：:Though the use of mobile devices (e.g., tablets, smartphones) by young children is pervasive and increasing, research relating children's use of mobile devices to their development is only beginning to emerge. Learning, language development, and self-regulation skills among children aged zero to five are of particular...
journal_title：Academic pediatrics
pub_type： 杂志文章,评审
doi：10.1016/j.acap.2021.01.007
更新日期：2021-01-21 00:00:00
abstract：OBJECTIVE:To determine the initial effectiveness of a novel, pediatric office-based intervention in motivating mothers to seek further assessment of positive depression screens. METHODS:In this pilot randomized controlled trial, English-speaking mothers (n = 104) with positive 2-question depression screens and present...
journal_title：Academic pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.acap.2014.11.008
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVE:Previous research suggests that cognitive functioning is associated with the risk of several adult psychiatric disorders. In this study we investigated whether adolescents who perform worse than expected at secondary school are at a higher risk for general mental health problems. METHODS:In a cross-sectional...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2017.04.016
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:The demand for global health electives among medical students and residents has grown substantially, yet perspectives of international hosts are not well documented. This study aimed to assess how host country supervising clinical preceptors perceive learners on short-term global health electives of up to 6 w...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2015.11.002
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:Use of complementary and alternative medical (CAM) therapies is common among adults with mental health concerns, but little is known about CAM use among adolescents with mental health concerns. METHODS:Data from the 2007 National Health Interview Survey were analyzed for youth from 7 to 17 years old. The st...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2013.05.001
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:There has been a rapid increase in the number of pediatric hospitalist programs in the United States. As most pediatric hospitalist services are believed to be subsidized by hospitals, gaining a better understanding of the rationale for these subsidies is critical to the future success and existence of these ...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2009.01.003
更新日期：2009-05-01 00:00:00
abstract：OBJECTIVE:There are many studies of the Pediatric Symptom Checklist (PSC), but none has followed a naturalistic sample longitudinally. We aimed to examine persistence and change in PSC scores over time in children seen in an ambulatory pediatric setting. METHODS:The sample of 1033 patients was PSC screened at 2 consec...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2009.03.004
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVE:Advocates must make decisions about the types of evidence they emphasize when communicating to cultivate support for adverse childhood experience (ACE) prevention policies. This study sought to characterize public perceptions of the persuasiveness of 12 ACE evidence statements and assess differences by ideolo...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2020.05.031
更新日期：2020-06-15 00:00:00
abstract：OBJECTIVE:Dermatologic complaints are common in outpatient pediatrics. However, pediatric dermatology specialty care can be difficult to access. We aimed to test the feasibility of co-locating dermatology services within primary care and increase the proportion of patients treated for basic skin complaints within the m...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2020.10.005
更新日期：2020-10-15 00:00:00
abstract：OBJECTIVE:Pediatricians have regular opportunities to perform screening dental examinations on young children and to educate families on preventive oral health. We sought to assess pediatricians' current attitudes and practices related to oral health of children 0-3 years old. METHODS:A Periodic Survey of Fellows, foc...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2009.09.016
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND:Adults tend to underestimate their personal risk of disease, but little is known about parents' perceptions of children's risk. METHODS:In total, 648 parents of children 0 to 18 years old attending 2 pediatric practices were surveyed about their children's exposure to smoking; 344 parents with children ≥2 y...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2018.09.008
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:Although it is known that children with mental health problems utilize primary care services more than most other children, it is unknown how addressing mental health problems in primary care affects children's subsequent services utilization. This study measures primary care utilization in the context of a r...
journal_title：Academic pediatrics
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.acap.2010.06.012
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:Limited English proficiency (LEP) is a known barrier to preventive care. Children from families with LEP face socioeconomic circumstances associated with increased odds of developmental delays and decreased participation in early care and education programs. Little is known about developmental surveillance a...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2015.12.007
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVES:The cognitive expertise of Pediatric Hospitalists (PH) lies not in standard knowledge but in making decisions under conditions of uncertainty. To maintain expertise, PH should engage in deliberate practice via self-assessments that promote higher-level cognitive processes necessary to address problems with m...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2020.10.003
更新日期：2020-10-14 00:00:00
abstract：BACKGROUND:Children with special health care needs (CSHCN) are at increased risk for functional disabilities. Care coordination has been shown to decrease unmet health service use but has yet been shown to improve functional status. We hypothesize that care coordination services lower the odds of functional disability ...
journal_title：Academic pediatrics
pub_type： 杂志文章
doi：10.1016/j.acap.2014.08.006
更新日期：2015-03-01 00:00:00
