Abstract:
BACKGROUND AND OBJECTIVES:Contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) is a novel technology that can identify subepithelial tumors (SETs) by detecting the degree of enhancement, but whether CEH-EUS can predict the malignancy risk of gastrointestinal stromal tumors (GISTs) remains unclear. The aim of our study was to evaluate the diagnostic accuracy of CEH-EUS and its ability to discriminate among SETs and predict the malignancy risk of GISTs. MATERIALS AND METHODS:We retrospectively included patients with suspected subepithelial lesions who underwent CEH-EUS preoperatively. Thirty-five patients with histologically proven GISTs and benign neoplasms were enrolled in the study. The images of CEH-EUS were categorized in accordance with microvasculature, parenchymal perfusion, and nonenhancing spots. The diagnostic performance of CEH-EUS was evaluated by comparing these findings with the histological diagnosis. RESULTS:When we divided the enrolled patients into high- and low-grade malignancy and benign groups, nonenhancing spots on CEH-EUS were found more frequently in the high-grade malignancy group (63.6%), followed by the low-grade malignancy (46.7%) and benign groups (25.7%) (P = 0.022). However, based on the statistical validity of the CEH-EUS findings for the discrimination of SETs, the sensitivity was 53.8% for diagnostic performance and 63.6% for prediction of malignancy risk of GISTs. CONCLUSIONS:From our study results, it is unclear whether CEH-EUS alone has a diagnostic role in the discrimination of SETs and the prediction of malignancy risk of GISTs. Further studies with larger samples from multiple centers and use of other imaging analysis modalities are needed.
journal_name
Endosc Ultrasoundjournal_title
Endoscopic ultrasoundauthors
Park HY,Jeon SW,Lee HS,Cho CM,Bae HI,Seo AN,Kweon OKdoi
10.4103/2303-9027.195871subject
Has Abstractpub_date
2016-11-01 00:00:00pages
384-389issue
6eissn
2303-9027issn
2226-7190pii
EndoscUltrasound_2016_5_6_384_195871journal_volume
5pub_type
杂志文章abstract::Endoscopic submucosal dissection (ESD) is an innovative advance in the treatment of early gastrointestinal (GI) cancer without lymph node metastases and precancerous lesions as it is an effective and safe therapeutic method. ESD has also been a promising therapeutic option for removal of submucosal tumors (SMTs) for i...
journal_title:Endoscopic ultrasound
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doi:10.4103/2303-9027.191606
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journal_title:Endoscopic ultrasound
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
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abstract::[This corrects the article DOI: 10.4103/eus.eus_9_19]. ...
journal_title:Endoscopic ultrasound
pub_type: 已发布勘误
doi:10.4103/2303-9027.282542
更新日期:2020-05-01 00:00:00
abstract::Lung cancer is one of the major causes of death in the world. Small cell carcinoma is the most aggressive type and can spread rapidly. The association of a small cell carcinoma with hepatic hilar metastasis and biliary obstruction is rare. Endoscopic ultrasound allows the aspiration of a cytology sample from adenopath...
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doi:10.4103/2303-9027.193570
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abstract::Insulinoma is the most common functioning islet cell tumor of the pancreas, with an annual incidence of 4 cases/1 million individuals. It is treated by surgical methods. Open surgery was once considered the standard approach for the treatment of insulinoma. However, the procedure is traumatic and requires a large inci...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
doi:10.4103/2303-9027.194703
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
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journal_title:Endoscopic ultrasound
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/2303-9027.163001
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章
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更新日期:2019-03-01 00:00:00
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journal_title:Endoscopic ultrasound
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更新日期:2019-09-01 00:00:00
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/2303-9027.144535
更新日期:2014-10-01 00:00:00
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/eus.eus_51_20
更新日期:2020-09-01 00:00:00
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:
更新日期:2014-04-01 00:00:00
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journal_title:Endoscopic ultrasound
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:Endoscopic ultrasound
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更新日期:2014-07-01 00:00:00
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章
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更新日期:2016-03-01 00:00:00
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.7178/eus.04.003
更新日期:2013-01-01 00:00:00
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journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
doi:10.7178/eus.03.003
更新日期:2012-10-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2013-07-01 00:00:00