Abstract:
OBJECTIVE:To assess the impact of gender upon the prognosis and medical care in a regional acute ST-elevation myocardial infarction management network. DESIGN:An observational study was made of consecutive patients entered in a prospective database. SCOPE:The Catalan acute ST-elevation myocardial infarction management network. PATIENTS:Patients treated between January 2010 and December 2011. INTERVENTIONS:Primary angioplasty, thrombolysis or conservative management. VARIABLES OF INTEREST:Time intervals, proportion and type of reperfusion, overall mortality, and in-hospital complication and overall mortality at 30 days and one year were compared in relation to gender. RESULTS:Of the 5,831 patients attended by the myocardial infarction network, 4,380 had a diagnosis of acute ST-elevation myocardial infarction, and 961 (21.9%) were women. Women were older (69.8±13.4 vs. 60.6±12.8 years; P<.001), had a higher prevalence of diabetes (27.1 vs. 18.1%, P<.001), Killip class>I (24.9 vs. 17.3%; P<.001) and no reperfusion (8.8 vs. 5.2%; P<.001) versus men. In addition, women had greater delays in medical care (first medical contact-to-balloon: 132 vs. 122min; P<.001, and symptoms onset-to-balloon: 236 vs. 210min; P<.001). Women presented higher percentages of overall in-hospital complications (20.6 vs. 17.4%; P=.031), in-hospital mortality (4.8 vs. 2.6%; P=.001), 30-day mortality (9.1 vs. 4.5%; P<.001) and one-year mortality (14.0 vs. 8.3%; P<.001) versus men. Nevertheless, after multivariate adjustment, no gender differences in 30-day and one-year mortality were observed. CONCLUSIONS:Despite a higher risk profile and poorer medical management, women present similar 30-day and one-year outcomes as their male counterparts in the context of the myocardial infarction management network.
journal_name
Med Intensivajournal_title
Medicina intensivaauthors
Fernández-Rodríguez D,Regueiro A,Cevallos J,Bosch X,Freixa X,Trilla M,Brugaletta S,Martín-Yuste V,Sabaté M,Bosa-Ojeda F,Masotti M,en representación de los investigadores del Registro Codi Infart.doi
10.1016/j.medin.2016.06.008subject
Has Abstractpub_date
2017-03-01 00:00:00pages
70-77issue
2eissn
0210-5691issn
1578-6749pii
S0210-5691(16)30136-Xjournal_volume
41pub_type
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