Respiratory drugs and macrolides prevent asthma exacerbations: A real-world investigation.

abstract：BACKGROUND:The need for additional research on symptomatic smokers with normal spirometry has been recently emphasized. Albeit not meeting criteria for Chronic obstructive pulmonary disease (COPD) diagnosis, symptomatic smokers may experience activity limitation, evidence of airway disease, and exacerbations. We, there...

journal_title：Respiratory medicine

authors： Di Marco F,Terraneo S,Job S,Rinaldo RF,Sferrazza Papa GF,Roggi MA,Santus P,Centanni S

更新日期：2017-06-01 00:00:00

abstract：:Pulmonary hypertension (PH) is a chronic cardiopulmonary disorder that if left untreated, progresses rapidly and is ultimately fatal. The World Health Organization (WHO) has classified PH into 5 distinct groups according to pathophysiology, hemodynamic characteristics, and clinical presentation. Dysfunction in the nit...

journal_title：Respiratory medicine

authors： Benza R,Mathai S,Nathan SD

更新日期：2017-01-01 00:00:00

abstract：:A multiplex polymerase chain reaction (PCR) was developed for the simultaneous detection of Chlamydia pneumoniae, Mycoplasma pneumoniae and Legionella pneumophila. Oligonucleotide primers for the amplification of the DNA of these three organisms were optimized for use in combination in the same reaction. PCR products ...

journal_title：Respiratory medicine

authors： Miyashita N,Saito A,Kohno S,Yamaguchi K,Watanabe A,Oda H,Kazuyama Y,Matsushima T,CAP Study Group.

更新日期：2004-06-01 00:00:00

abstract：UNLABELLED:Amiodarone-induced pulmonary toxicity (APT) is a serious adverse event that can lead to death. The aims of our study are to determine factors associated with mortality and to describe outcome and sequelae of patients with APT. METHODS:Forty-six patients with APT were divided into two groups according to sur...

journal_title：Respiratory medicine

authors： Mankikian J,Favelle O,Guillon A,Guilleminault L,Cormier B,Jonville-Béra AP,Perrotin D,Diot P,Marchand-Adam S

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Neurocognitive impairment has been described in COPD patients, but little is known about its relationship with physical functioning and health-related quality of life (HRQL) in this chronically ill patient group. METHODS:301 stable COPD patients completed the Trail Making Test (TMT-A: psychomotor speed and ...

journal_title：Respiratory medicine

authors： Schure MB,Borson S,Nguyen HQ,Trittschuh EH,Thielke SM,Pike KC,Adams SG,Fan VS

更新日期：2016-05-01 00:00:00

abstract：:The accuracy of prescriptions for bronchodilator drugs was monitored before and after an educational circular to the medical staff of five medical wards. The circular contained model prescriptions for beta-agonists alone and combined with ipratropium bromide. There was a significant improvement overall in the accuracy...

journal_title：Respiratory medicine

authors： Craig IR,Riley MR,Cooke NJ

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:Sleep disorders have a high prevalence among patients with idiopathic pulmonary fibrosis (IPF). The prevalence of restless legs syndrome (RLS) is not known in these patients, neither is its clinical impact as a comorbidity. We investigated the association of RLS with IPF and characterized the clinical feature...

journal_title：Respiratory medicine

authors： Varone F,Friello L,Di Blasi C,Sgalla G,Luigetti M,Iovene B,Richeldi L,Della Marca G,Brunetti V

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:The release of tumor necrosis factor (TNF-alpha) is increased in sarcoidosis patients. TNF-alpha exerts its effect by binding to specific cell surface receptors. There are only fragmentary data concerning the expression of tumor necrosis factor receptors (TNFRs) on bronchoalveolar lavage fluid (BALF) and p...

journal_title：Respiratory medicine

authors： Kieszko R,Krawczyk P,Chocholska S,Bojarska-Junak A,Jankowska O,Król A,Roliński J,Milanowski J

更新日期：2007-03-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is commonly associated with asthma; however, frequency in nonatopic children with asthmatic symptoms is unknown. The aim of this study was to determine the frequency of gastroesophageal reflux (GER) in nonatopic children with asthma-like airway disease that recur despite conventi...

journal_title：Respiratory medicine

authors： Yüksel H,Yilmaz O,Kirmaz C,Aydoğdu S,Kasirga E

更新日期：2006-03-01 00:00:00

abstract：:To determine if shortcomings in asthma management in the Accident and Emergency (A & E) department identified in a previous (1983) study (Reed et al. Thorax 1985; 40: 897-902) had been corrected, we retrospectively reviewed the case records of patients attending with asthma between December 1987 and November 1988. The...

journal_title：Respiratory medicine

authors： Chidley KE,Wood-Baker R,Town GI,Sleet RA,Holgate ST

更新日期：1991-09-01 00:00:00

abstract：:The objective of this study was to describe asthma exacerbation self-management in children and adolescents. We used a cross-sectional study population enrolled in the International Study of Asthma and Allergies in Childhood (ISAAC) in Bordeaux. Subjects answered an additional questionnaire on utilization of health se...

journal_title：Respiratory medicine

authors： Raherison C,Tunon-de-Lara JM,Vernejoux JM,Taytard A

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Patients with idiopathic pulmonary fibrosis (IPF) present an important ventilatory limitation reducing their exercise capacity. Non-invasive ventilatory support has been shown to improve exercise capacity in patients with obstructive diseases; however, its effect on IPF patients remains unknown. OBJECTIVE:T...

journal_title：Respiratory medicine

authors： Moderno EV,Yamaguti WP,Schettino GP,Kairalla RA,Martins MA,Carvalho CR,Carvalho CR

更新日期：2010-01-01 00:00:00

abstract：:We aimed to study trends in gender-related differences in incidence, and prevalence for long-term oxygen therapy due to chronic obstructive pulmonary disease. Another aim was to study survival after onset of oxygen therapy. Prospectively followed were 5689 Swedish patients, who were prescribed oxygen therapy because o...

journal_title：Respiratory medicine

authors： Franklin KA,Gustafson T,Ranstam J,Ström K

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Bronchiectasis is a common disabling but rarely fatal disease. However the long-term prognosis and risk factors for mortality are not well known. OBJECTIVE:The aim of this study was to determine prospectively the survival and predictive factors of mortality in patients with bronchiectasis, during 4-year fol...

journal_title：Respiratory medicine

authors： Onen ZP,Gulbay BE,Sen E,Yildiz OA,Saryal S,Acican T,Karabiyikoglu G

更新日期：2007-07-01 00:00:00

abstract：:The principals of rehabilitation medicine are to prevent muscle atrophy and improve mobility. Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with muscle atrophy and yet many patients do not undergo pulmonary rehabilitation until they have been in stable health for some time. We investigat...

journal_title：Respiratory medicine

authors： Murphy N,Bell C,Costello RW

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:An increasing number of studies confirm that pathogenesis and prevalence of bronchial asthma are age and sex dependent. Detailed physiological mechanisms of the changing sex ratios with age are not fully known, however, the gender (socio-cultural) factors are also imperative. Although multiple factors defini...

journal_title：Respiratory medicine

authors： Lux R,Awa W,Walter U

更新日期：2009-05-01 00:00:00

abstract：:The fraction of the emitted dose from an inhaler that has the potential to be deposited into the lungs is known as the fine particle dose (also the respirable dose). During inhalation all dry powder inhalers require a 'force' to be created inside the device so that a fine particle dose is generated from the formulatio...

journal_title：Respiratory medicine

authors： Chrystyn H

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:A simple rule based on short-acting inhaled β2-agonist (SABA) use could identify patients with chronic obstructive pulmonary disease (COPD) at increased risk of exacerbations and signal the need for maintenance therapy change, similar to asthma "Rules of Two(®)". METHODS:Associations between SABA use, COPD ...

journal_title：Respiratory medicine

authors： Sharafkhaneh A,Altan AE,Colice GL,Hanania NA,Donohue JF,Kurlander JL,Rodriguez-Roisin R,Altman PR

更新日期：2014-09-01 00:00:00

abstract：:To answer the question as to whether pulmonary rehabilitation programs (PRP) induced increase in exercise tolerance (ET) is associated with increased levels of exhaled nitric oxide (eNO) in COPD patients of different degrees of severity, we designed a prospective and controlled study. Forty-seven stable COPD patients ...

journal_title：Respiratory medicine

authors： Clini E,Bianchi L,Foglio K,Vitacca M,Ambrosino N

更新日期：2002-05-01 00:00:00

abstract：:Along with the aging population, the public health burden of cerebrovascular disease is increasing. Cerebral small vessel disease and accumulation of brain pathology associate with cognitive decline and can lead to clinical outcomes, such as stroke and dementia. Chronic Obstructive Pulmonary Disease (COPD) is a common...

journal_title：Respiratory medicine

authors： Lahousse L,Tiemeier H,Ikram MA,Brusselle GG

更新日期：2015-11-01 00:00:00

abstract：:The differential diagnosis of pleural masses is limited. Asbestos-related disease and invasive bronchogenic carcinoma make up the majority of cases. The diagnostic yield of biopsies is low, and invasive procedures are often required to achieve diagnosis. A variety of imaging techniques are available to help differenti...

journal_title：Respiratory medicine

authors： Bruns AS,Mastronarde JG

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Although respiratory muscle weakness (RMW) is known to predict prognosis in patients with heart failure with reduced ejection fraction (HFrEF), RMW prevalence and its prognosis in those with preserved ejection fraction (HFpEF) remain unknown. We aimed to investigate whether the RMW predicted mortality in HFp...

journal_title：Respiratory medicine

authors： Hamazaki N,Kamiya K,Matsuzawa R,Nozaki K,Ichikawa T,Tanaka S,Nakamura T,Yamashita M,Maekawa E,Noda C,Yamaoka-Tojo M,Matsunaga A,Masuda T,Ako J

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:An ongoing outbreak of coronavirus disease 2019 (COVID-19) has spread around the world. It is debatable whether asymptomatic COVID-19 virus carriers are contagious. We report here a case of the asymptomatic patient and present clinical characteristics of 455 contacts, which aims to study the infectivity of a...

journal_title：Respiratory medicine

authors： Gao M,Yang L,Chen X,Deng Y,Yang S,Xu H,Chen Z,Gao X

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:Idiopathic bronchiectasis is a poorly defined disease characterised by persistent inflammation, infection and progressive lung damage. Natural killer (NK) cells provide a major defense against infection, through the interaction of their surface receptors, including the activating and inhibitory killer immu...

journal_title：Respiratory medicine

authors： McDonnell MJ,Anwar GA,Rutherford RM,De Soyza A,Worthy S,Corris PA,Lordan JL,Bourke S,Afolabi G,Ward C,Middleton P,Middleton D

更新日期：2014-08-01 00:00:00

abstract：:Previous studies of acupuncture in asthma have reported conflicting results, some claiming benefit for some patients. We conducted a randomized, double-blind (patient and evaluator) study in 23 non-smoking asthmatics (10 M; 13 F) aged 43 +/- 15 years with forced expiratory volume in 1 s (FEV1) 59 +/- 16% pred. After i...

journal_title：Respiratory medicine

authors： Biernacki W,Peake MD

更新日期：1998-09-01 00:00:00

abstract：:To clarify the clinical features of pulmonary Mycobacterium avium-intracellulare complex (MAC) infection, we retrospectively evaluated clinical manifestations, laboratory data, chest and maxillary sinus computed tomographic scans and induced sputum findings in 26 with MAC infection in comparison with 104 patients with...

journal_title：Respiratory medicine

authors： Watanabe K,Fujimura M,Kasahara K,Yasui M,Myou S,Watanabe A,Nakao S

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:To assess the utility of capsaicin test in the differential diagnosis of non-productive causes of chronic cough and to examine the effects of treatment on this reflex. PARTICIPANTS:86 healthy volunteers and 101 patients with chronic cough: asthma (n: 54) gastroesophageal reflux (n: 35) and post-nasal drip s...

journal_title：Respiratory medicine

authors： Nieto L,de Diego A,Perpiñá M,Compte L,Garrigues V,Martínez E,Ponce J

更新日期：2003-04-01 00:00:00

abstract：INTRODUCTION:To provide optimal care for patients with chronic obstructive pulmonary disease physicians need to understand if their patients benefit from an intervention. The objective of this study was to assess agreement between patients and physicians on health-related quality of life (HRQL) changes in response to r...

journal_title：Respiratory medicine

authors： Puhan MA,Behnke M,Devereaux PJ,Montori VM,Braendli O,Frey M,Schünemann HJ

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The choice of inhaler device for asthma patients depends upon multiple attributes. We investigated factors that may drive general practitioners (GPs) and respiratory specialists in the prescription of inhaler devices for asthma patients who initiated inhalation therapy. METHODS:We retrospectively analysed p...

journal_title：Respiratory medicine

authors： Lavorini F,Bianco A,Blasi F,Braido F,Corsico AG,Di Marco F,Gentile A,Paggiaro PL,Pegoraro V,Pelaia G,Rogliani P,Santus P,Scichilone N,Soldi A,Canonica GW

更新日期：2020-05-01 00:00:00

abstract：:Lung function (FEV1 before and after bronchodilatation) was studied prospectively over five visits in 55 asthmatic children (28 boys) from childhood to adulthood (age 30). At the last follow-up recordings were made at rest, after cold air challenge (CACh), and after bronchodilatation. Results were related to clinical ...

journal_title：Respiratory medicine

authors： Gustafsson PM,Kjellman B

更新日期：2000-05-01 00:00:00