Abstract:
:Analyzing the concentrations of heavy metals in the sera of umbilical cord blood samples can provide useful information about prenatal exposure to environmental agents. An analytical method based on ICP-MS to simultaneously determine multiple elements in umbilical cord blood samples was developed for assessing the in utero exposure to metallic and metalloid elements. The method only required as little as 100 μL of serum diluted 1:25 for direct analysis. Matrix-matched protocol was used to eliminate mass matrix interference and kinetic energy discrimination mode was used to eliminate the polyatomic ion interference. The assay was completed on average within 4 min with the detection limits ranging from 0.0002 to 44.4 μg/L for all the targeted elements. The detection rates for most of elements were 100 % other than cadmium (Cd), lead (Pb), and mercury (Hg). The testing results of the certified reference materials were ideal. The method is simple and sensitive, so it is suitable for the monitoring of large quantities of samples.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Liang C,Li Z,Xia X,Wang Q,Tao R,Tao Y,Xiang H,Tong S,Tao Fdoi
10.1007/s12011-016-0853-6subject
Has Abstractpub_date
2017-05-01 00:00:00pages
1-8issue
1eissn
0163-4984issn
1559-0720pii
10.1007/s12011-016-0853-6journal_volume
177pub_type
杂志文章abstract::Cadmium (Cd) is an environmental toxicant and an inflammation-related xenobiotic. Selenium (Se) is a well-known nutritional trace element and a potent chemopreventive agent. The present study aimed to investigate the effect of Se on the cytotoxicity of Cd in bird immunocytes in vitro. Chicken splenic lymphocytes expos...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0354-z
更新日期:2015-11-01 00:00:00
abstract::Trientine((R)) is not an effective drug for the treatment of intractable hand dermatitis in nickel-sensitive patients. In a controlled, double-blind study this chelator, on oral administration, failed to stimulate nickel excretion. Early morning urine samples from two groups of nine patients were analyzed by atomic ab...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02795597
更新日期:1987-10-01 00:00:00
abstract::Selenomethionine metabolism and the biochemical basis for its cytotoxicity were analyzed in cultured human and murine lymphoid cells. The metabolic pathways were also addressed, using purified mammalian enzymes and crude tissue extracts. Selenomethionine was found to be effectively metabolized to S-adenosylmethionine ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990463
更新日期:1991-01-01 00:00:00
abstract::An external-sample liquid scintillation (LS) counting for the gamma emitter 75Se has been developed. An expressly designed well-type LS vial and a 2,5-diphenyoxazole-1,4-bis(5-phenyl-2-oxazoyl)-benzene-xylene solution containing 35% tertrabutylzinn allow 75Se to be counted in a standard LS counter with counting effici...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:77:3:287
更新日期:2000-12-01 00:00:00
abstract::Concentrations of trace metals (Cu, Pb, Zn, Cd, Cr, Hg, and As) were determined for the first time in seawater, sediment, and Manila clam from Deer Island, Liaoning Province, China. The seawater, sediment, and clam samples were collected seasonally at three clam farming sites around Deer Island during 2010-2011. The a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9628-5
更新日期:2013-06-01 00:00:00
abstract::Strontium (Sr) ralenate is a new agent used for the prevention and treatment of osteoporosis. As a bone-seeking element, 98% of Sr is deposited in the bone and teeth after oral ingestion. However, the effect of Sr treatment on bone microarchitecture and bone nanomechanical properties remains unclear. In this study, 18...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9158-y
更新日期:2012-01-01 00:00:00
abstract::This study investigated the effects of ethanol (EtOH) on manganese (Mn)-induced striatal toxicity in rat by evaluating the neurobehavioral changes, biochemical and molecular events in rats exposed to Mn alone at 30 mg/kg, or their combination with EtOH at 1.25- and 5-g/kg body weight for 35 consecutive days. Locomotiv...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1587-4
更新日期:2019-09-01 00:00:00
abstract::The effect of manganese (Mn) supplementation on bone mineral density (BMD) and bone metabolism parameters was determined in ovariectomized Sprague-Dawley rats. Rats were divided into four groups (OVX, OVX+Mn, sham, sham+Mn) and fed with different intake levels of manganese (adequate 0.001% Mn, supplementation 0.01% Mn...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8119-6
更新日期:2008-07-01 00:00:00
abstract::Leukocytes incubated with Cu(II) showed a decrease in both glutathione reductase activity and reduced glutathione content. The glucose 6-phosphate dehydrogenase activity under the same conditions was not affected. Serum albumin added to mixtures prevented the loss of enzyme activity, whileD-penicillamine andL-histidin...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783258
更新日期:1982-06-01 00:00:00
abstract::The effects of cobaltous chloride in inducing chromosomal aberrations were observed on laboratory bred mice in vivo after single oral administration of different fractions (1/10, 1/20, 1/40) of the lethal toxic dose of the salt. Bone marrow cells were flushed out and processed for chromosome studies following colchici...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF03032691
更新日期:1991-05-01 00:00:00
abstract::The hypothesis was tested that marginal copper deficiency affects iron status. Copper restriction (1 vs 5 mg Cu/kg diet) significantly lowered iron concentrations and transferrin saturation in plasma and reduced blood hemoglobin, hematocrit, and iron concentrations in tibia and femur, but raised iron concentrations in...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02786240
更新日期:1992-10-01 00:00:00
abstract::Selenium (Se) deficiency in the experimental models, Coturnix coturnix japonica and Corcyra cephalonica, resulted in impaired mitochondrial substrate oxidations and lowered thiol levels. Studies with respiratory inhibitors confirmed reduced mitochondrial electron transport enzyme activities, especially at cytochrome c...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784077
更新日期:1996-03-01 00:00:00
abstract::The purpose of this 42-day study was to examine the effect of dietary vanadium on the ileac T cells and contents of cytokines including interleukin-2 (IL-2), interleukin-6 (IL-6), and interferon-gamma (IFN-γ) in broilers by flow cytometry and enzyme-linked immunosorbent assay. A total of 420 one-day-old avian broilers...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9274-8
更新日期:2012-06-01 00:00:00
abstract::Antagonistic interactions between silicon and aluminum occur in living organisms. Thus, an experiment was performed to ascertain whether high dietary aluminum would accentuate the signs of silicon deprivation in rats and conversely whether silicon deprivation would accentuate the response to high dietary aluminum. The...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917430
更新日期:1994-06-01 00:00:00
abstract::The effect of ad libitum ingestion of selenium (Se) in drinking water (0.15 mg SeO2/L) for 3 wk on the brain weight, total brain protein, glutathione (GSH) level, catalase activity, and lipid peroxidation in the brain of protein-undernourished (PU) rats was investigated, in an attempt to determine whether antioxidants...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02685933
更新日期:2007-05-01 00:00:00
abstract::The degree of accumulation and distribution of Cd and Pb in the organs of young animals compared to the amount taken in with water or feed have not been thoroughly investigated yet. The experiment aimed to verify whether the source of toxic metals (feed, drinking water) administered to growing rats orally has an influ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0414-4
更新日期:2016-02-01 00:00:00
abstract::This study was performed with the aim of investigating the concentration of zinc and copper in the blood of healthy alpacas (Vicugna pacos) kept in central Europe and to compare the concentration of Zn and Cu in plasma and in whole blood. A further objective was to evaluate blood Zn and Cu in relation to different mic...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1043-x
更新日期:2018-02-01 00:00:00
abstract::The element Zn is the metal component or activator of many important enzymes. The tissue concentrations and activities of Zn metalloenzymes direct the rate of protein and nucleic acid syntheses, thereby influencing tissue growth and reperative processes. Most of the serum Zn is normally bound to circulating proteins. ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02786257
更新日期:1996-08-01 00:00:00
abstract::Nano-titanium dioxide is a kind of widely used nanomaterial that exhibits various adverse outcomes. However, the role of oxidative stress in this regard remains controversial. This study aimed to evaluate whether oxidative stress is one of the toxicity mechanisms induced by nano-titanium dioxide in rats and mice model...
journal_title:Biological trace element research
pub_type: 杂志文章,meta分析
doi:10.1007/s12011-019-01761-z
更新日期:2020-03-01 00:00:00
abstract::The biological function of selenium (Se) is mainly elicited through Se-containing proteins. Selenoprotein W (SelW), one member of the selenoprotein family, is essential for the normal function of the skeletal muscle system. To investigate the possible relationship of Se in the process of differentiation in chicken myo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9520-8
更新日期:2012-12-01 00:00:00
abstract::The objective of this study was to investigate the iron source absorption in the small intestine of broiler. In situ ligated intestinal loops of 70 birds were poured into one of seven solutions, including inorganic iron (FeSO4, Fe2(SO4)3), organic Fe glycine chelate (Fe-Gly(II), Fe-Gly(III)), the mixtures (FeSO4 with ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0179-1
更新日期:2015-02-01 00:00:00
abstract::Since waterborne minerals appear in ionic form and are readily absorbed by the gastrointestinal tract, drinking water could be a crucial source of mineral intake. However, no comprehensive research has yet determined how trace elements in drinking water relate to body composition. We aimed to assess the relationship b...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-016-0779-z
更新日期:2017-02-01 00:00:00
abstract::The binding of selenite, the form of selenium used in the treatment of Keshan disease, to plasma proteins and the role of erythrocytes in this process have been studied. The experiments were carried out by incubating 75Se as selenite with plasma and whole blood in vitro (human and rat) and in vivo (rat) and subsequent...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990129
更新日期:1988-01-01 00:00:00
abstract::Among the trace elements, zinc is one of the most used elements in biological systems. Zinc is found in the structure of more than 2700 enzymes, including hydrolases, transferases, oxyreductases, ligases, isomerases, and lyases. Not surprisingly, it is present in almost all body cells. Preserving the stability and int...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1007/s12011-017-1119-7
更新日期:2018-05-01 00:00:00
abstract::The aim of this study was to compare zinc, copper, lead, cadmium, and mercury concentrations in the bones of long-living mammals-humans (Homo sapiens) and Canidae (dogs Canis familiaris and foxes Vulpes vulpes) from northwestern Poland and to determine the usefulness of Canidae as bioindicators of environmental exposu...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9615-x
更新日期:2013-05-01 00:00:00
abstract::It has been demonstrated that zinc exerts its beneficial influence on skin fibroblasts. Propolis, a complex mixture of plant-derived and bees' products, was reported to stimulate cicatrization processes in skin and prevent infections. The aim of this study was to find out how zinc and propolis influence human skin fib...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0019-3
更新日期:2014-07-01 00:00:00
abstract::Selenoprotein T (SelT) is associated with the regulation of calcium homeostasis and neuroendocrine secretion. SelT can also change cell adhesion and is involved in redox regulation and cell fixation. However, the structure and function of chicken SelT and its response to selenium (Se) remains unclear. In the present s...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0049-x
更新日期:2014-08-01 00:00:00
abstract::The association between serum copper and zinc concentrations and age, sex, and other risk factors of cardiovascular disease in randomly selected adult volunteers aged 19-59 were investigated. There was a positive relationship between copper and age in both sexes, but zinc was negatively correlated with age in males on...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02950795
更新日期:1994-03-01 00:00:00
abstract::In brain, excess zinc alters the metabolism of amyloid precursor protein, leading to β-amyloid protein deposition, one of the hallmarks of Alzheimer's disease (AD) pathology. Recently, it has been reported that zinc accelerates in vitro tau fibrillization, another hallmark of AD. In the current study, we examined the ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9411-z
更新日期:2012-11-01 00:00:00
abstract::The metabolism of 203Hg-labeled methylmercury chloride (MeHg) has been studied in rabbits and hamsters. Rabbits were administered 1.6 mumols MeHgCl/kg bw intravenously, and hamsters 40 mumols/kg bw orally. Urine and feces were collected daily and groups of four animals killed after 1 h, 1 d, or 7 d. The concentration ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917256
更新日期:1989-07-01 00:00:00